PF3D7_1128400 (FPPS/GGPPS)

Aliases : FPPS/GGPPS

Description : SSF48576: Isoprenoid synthase domain superfamily. Pfam domain(s): PF00348: Polyprenyl synthetase.

Gene families : OG_01_0001109 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001109_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1128400
Cluster	P. falciparum: Cluster_30

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004311	farnesyltranstransferase activity	IDA	PlasmoDB
MF	GO:0004337	geranyltranstransferase activity	IDA	PlasmoDB
MF	GO:0004659	prenyltransferase activity	None	Extended
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006720	isoprenoid metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008299	isoprenoid biosynthetic process	IDA	PlasmoDB
BP	GO:0008299	isoprenoid biosynthetic process	IEA	Interproscan predictions
BP	GO:0008299	isoprenoid biosynthetic process	IEA	PlasmoDB
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	None	Extended
BP	GO:0035690	cellular response to drug	IDA	PlasmoDB
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042493	response to drug	IDA	PlasmoDB
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0070887	cellular response to chemical stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0000338	protein deneddylation	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0004221	obsolete ubiquitin thiolesterase activity	IEP	Predicted GO
MF	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	IEP	Predicted GO
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEP	Predicted GO
BP	GO:0006486	protein glycosylation	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006743	ubiquinone metabolic process	IEP	Predicted GO
BP	GO:0006744	ubiquinone biosynthetic process	IEP	Predicted GO
BP	GO:0006873	cellular ion homeostasis	IEP	Predicted GO
BP	GO:0006885	regulation of pH	IEP	Predicted GO
BP	GO:0007035	vacuolar acidification	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009233	menaquinone metabolic process	IEP	Predicted GO
BP	GO:0009234	menaquinone biosynthetic process	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
BP	GO:0016579	protein deubiquitination	IEP	Predicted GO
MF	GO:0016758	transferase activity, transferring hexosyl groups	IEP	Predicted GO
MF	GO:0019783	ubiquitin-like protein-specific protease activity	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0030003	cellular cation homeostasis	IEP	Predicted GO
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0030641	regulation of cellular pH	IEP	Predicted GO
MF	GO:0032182	ubiquitin-like protein binding	IEP	Predicted GO
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Predicted GO
CC	GO:0033180	proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
MF	GO:0036442	proton-exporting ATPase activity	IEP	Predicted GO
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEP	Predicted GO
BP	GO:0042180	cellular ketone metabolic process	IEP	Predicted GO
BP	GO:0042181	ketone biosynthetic process	IEP	Predicted GO
MF	GO:0043130	ubiquitin binding	IEP	Predicted GO
BP	GO:0043248	proteasome assembly	IEP	Predicted GO
BP	GO:0043413	macromolecule glycosylation	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
MF	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	IEP	Predicted GO
BP	GO:0045851	pH reduction	IEP	Predicted GO
MF	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
BP	GO:0050801	ion homeostasis	IEP	Predicted GO
BP	GO:0051452	intracellular pH reduction	IEP	Predicted GO
BP	GO:0051453	regulation of intracellular pH	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0055067	monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0055080	cation homeostasis	IEP	Predicted GO
BP	GO:0055082	cellular chemical homeostasis	IEP	Predicted GO
BP	GO:0070085	glycosylation	IEP	Predicted GO
BP	GO:0070646	protein modification by small protein removal	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
BP	GO:0098771	inorganic ion homeostasis	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
MF	GO:0101005	ubiquitinyl hydrolase activity	IEP	Predicted GO
BP	GO:1901661	quinone metabolic process	IEP	Predicted GO
BP	GO:1901663	quinone biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000092	Polyprenyl_synt	47	330

External Links

PlasmoDB	810842
PlasmoDB	PF11_0295

PF3D7_1128400 (FPPS/GGPPS)

Expression Profile

Co-expression Networks

Functional Annotation