PF3D7_1129000 (SpdSyn)


Aliases : SpdSyn

Description : SSF53335: S-adenosyl-L-methionine-dependent methyltransferase. Pfam domain(s): PF01564: Spermine/spermidine synthase domain, PF17284: Spermidine synthase tetramerisation domain.


Gene families : OG_01_0003782 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0003782_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_1129000
Cluster P. falciparum: Cluster_28

Target Alias Description ECC score Gene Family Method Actions
PBANKA_0919300 No alias SSF53335: S-adenosyl-L-methionine-dependent... 0.06 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA PlasmoDB
MF GO:0004766 spermidine synthase activity IDA PlasmoDB
CC GO:0005737 cytoplasm IDA PlasmoDB
BP GO:0008295 spermidine biosynthetic process IDA PlasmoDB
Type GO Term Name Evidence Source
BP GO:0000122 negative regulation of transcription by RNA polymerase II IEP Predicted GO
BP GO:0000245 spliceosomal complex assembly IEP Predicted GO
CC GO:0000323 lytic vacuole IEP Predicted GO
BP GO:0001817 regulation of cytokine production IEP Predicted GO
BP GO:0001818 negative regulation of cytokine production IEP Predicted GO
MF GO:0003714 transcription corepressor activity IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0004352 glutamate dehydrogenase (NAD+) activity IEP Predicted GO
MF GO:0004353 glutamate dehydrogenase [NAD(P)+] activity IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0004814 arginine-tRNA ligase activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005261 cation channel activity IEP Predicted GO
MF GO:0005262 calcium channel activity IEP Predicted GO
MF GO:0005353 fructose transmembrane transporter activity IEP Predicted GO
MF GO:0005355 glucose transmembrane transporter activity IEP Predicted GO
CC GO:0005741 mitochondrial outer membrane IEP Predicted GO
CC GO:0005742 mitochondrial outer membrane translocase complex IEP Predicted GO
CC GO:0005764 lysosome IEP Predicted GO
CC GO:0005767 secondary lysosome IEP Predicted GO
CC GO:0005773 vacuole IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005850 eukaryotic translation initiation factor 2 complex IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006420 arginyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006536 glutamate metabolic process IEP Predicted GO
BP GO:0006874 cellular calcium ion homeostasis IEP Predicted GO
BP GO:0006875 cellular metal ion homeostasis IEP Predicted GO
MF GO:0008524 glucose 6-phosphate:phosphate antiporter activity IEP Predicted GO
BP GO:0008643 carbohydrate transport IEP Predicted GO
BP GO:0008645 hexose transmembrane transport IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
MF GO:0009670 triose-phosphate:phosphate antiporter activity IEP Predicted GO
CC GO:0009986 cell surface IEP Predicted GO
BP GO:0010558 negative regulation of macromolecule biosynthetic process IEP Predicted GO
MF GO:0015085 calcium ion transmembrane transporter activity IEP Predicted GO
MF GO:0015103 inorganic anion transmembrane transporter activity IEP Predicted GO
MF GO:0015114 phosphate ion transmembrane transporter activity IEP Predicted GO
MF GO:0015144 carbohydrate transmembrane transporter activity IEP Predicted GO
MF GO:0015145 monosaccharide transmembrane transporter activity IEP Predicted GO
MF GO:0015149 hexose transmembrane transporter activity IEP Predicted GO
MF GO:0015267 channel activity IEP Predicted GO
MF GO:0015301 anion:anion antiporter activity IEP Predicted GO
MF GO:0015315 organophosphate:inorganic phosphate antiporter activity IEP Predicted GO
BP GO:0015749 monosaccharide transmembrane transport IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0016272 prefoldin complex IEP Predicted GO
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEP Predicted GO
MF GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
CC GO:0019867 outer membrane IEP Predicted GO
CC GO:0020020 food vacuole IEP Predicted GO
BP GO:0020027 hemoglobin metabolic process IEP Predicted GO
CC GO:0020030 infected host cell surface knob IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
MF GO:0022803 passive transmembrane transporter activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
CC GO:0030139 endocytic vesicle IEP Predicted GO
BP GO:0030150 protein import into mitochondrial matrix IEP Predicted GO
CC GO:0030176 integral component of endoplasmic reticulum membrane IEP Predicted GO
CC GO:0030430 host cell cytoplasm IEP Predicted GO
CC GO:0031227 intrinsic component of endoplasmic reticulum membrane IEP Predicted GO
CC GO:0031300 intrinsic component of organelle membrane IEP Predicted GO
CC GO:0031301 integral component of organelle membrane IEP Predicted GO
CC GO:0031350 intrinsic component of plastid membrane IEP Predicted GO
CC GO:0031351 integral component of plastid membrane IEP Predicted GO
CC GO:0031354 intrinsic component of plastid outer membrane IEP Predicted GO
CC GO:0031355 integral component of plastid outer membrane IEP Predicted GO
CC GO:0031410 cytoplasmic vesicle IEP Predicted GO
CC GO:0031968 organelle outer membrane IEP Predicted GO
CC GO:0031982 vesicle IEP Predicted GO
CC GO:0032010 phagolysosome IEP Predicted GO
BP GO:0032469 endoplasmic reticulum calcium ion homeostasis IEP Predicted GO
BP GO:0032675 regulation of interleukin-6 production IEP Predicted GO
BP GO:0032715 negative regulation of interleukin-6 production IEP Predicted GO
BP GO:0032780 negative regulation of ATPase activity IEP Predicted GO
CC GO:0033647 host intracellular organelle IEP Predicted GO
CC GO:0033648 host intracellular membrane-bounded organelle IEP Predicted GO
CC GO:0033655 host cell cytoplasm part IEP Predicted GO
BP GO:0034219 carbohydrate transmembrane transport IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0035915 pore formation in membrane of other organism IEP Predicted GO
BP GO:0042221 response to chemical IEP Predicted GO
BP GO:0042493 response to drug IEP Predicted GO
BP GO:0042540 hemoglobin catabolic process IEP Predicted GO
BP GO:0042592 homeostatic process IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
BP GO:0043086 negative regulation of catalytic activity IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043230 extracellular organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0043462 regulation of ATPase activity IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0044092 negative regulation of molecular function IEP Predicted GO
CC GO:0044161 host cell cytoplasmic vesicle IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
CC GO:0044421 extracellular region part IEP Predicted GO
CC GO:0044435 plastid part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
BP GO:0044657 pore formation in membrane of other organism during symbiotic interaction IEP Predicted GO
BP GO:0044658 pore formation in membrane of host by symbiont IEP Predicted GO
BP GO:0044743 protein transmembrane import into intracellular organelle IEP Predicted GO
CC GO:0045335 phagocytic vesicle IEP Predicted GO
BP GO:0045892 negative regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0046323 glucose import IEP Predicted GO
BP GO:0048519 negative regulation of biological process IEP Predicted GO
MF GO:0051087 chaperone binding IEP Predicted GO
MF GO:0051119 sugar transmembrane transporter activity IEP Predicted GO
BP GO:0051239 regulation of multicellular organismal process IEP Predicted GO
BP GO:0051241 negative regulation of multicellular organismal process IEP Predicted GO
BP GO:0051253 negative regulation of RNA metabolic process IEP Predicted GO
BP GO:0051346 negative regulation of hydrolase activity IEP Predicted GO
BP GO:0051673 membrane disruption in other organism IEP Predicted GO
BP GO:0052025 modification by symbiont of host cell membrane IEP Predicted GO
BP GO:0052043 modification by symbiont of host cellular component IEP Predicted GO
BP GO:0052111 modification by symbiont of host structure IEP Predicted GO
BP GO:0052185 modification of structure of other organism involved in symbiotic interaction IEP Predicted GO
BP GO:0052188 modification of cellular component in other organism involved in symbiotic interaction IEP Predicted GO
BP GO:0052332 modification by organism of membrane in other organism involved in symbiotic interaction IEP Predicted GO
BP GO:0055065 metal ion homeostasis IEP Predicted GO
BP GO:0055074 calcium ion homeostasis IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
MF GO:0071917 triose-phosphate transmembrane transporter activity IEP Predicted GO
BP GO:0072503 cellular divalent inorganic cation homeostasis IEP Predicted GO
BP GO:0072507 divalent inorganic cation homeostasis IEP Predicted GO
CC GO:0097619 PTEX complex IEP Predicted GO
CC GO:0097708 intracellular vesicle IEP Predicted GO
CC GO:0098799 outer mitochondrial membrane protein complex IEP Predicted GO
MF GO:0099516 ion antiporter activity IEP Predicted GO
MF GO:0140110 transcription regulator activity IEP Predicted GO
BP GO:1902679 negative regulation of RNA biosynthetic process IEP Predicted GO
BP GO:1903507 negative regulation of nucleic acid-templated transcription IEP Predicted GO
CC GO:1903561 extracellular vesicle IEP Predicted GO
BP GO:1904659 glucose transmembrane transport IEP Predicted GO
BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR035246 Spermidine_synt_N 43 96
PlasmoDB 810848
PlasmoDB PF11_0301