PF3D7_1138400 (GCalpha)

Aliases : GCalpha

Description : SSF81665: "P-type ATPase, transmembrane domain superfamily", SSF56784: HAD-like superfamily, SSF81653: "P-type ATPase, A domain superfamily", SSF55073: Nucleotide cyclase. Pfam domain(s): PF00211: Adenylate and Guanylate cyclase catalytic domain, PF16212: Phospholipid-translocating P-type ATPase C-terminal, PF00122: E1-E2 ATPase.

Gene families : OG_01_0001081 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001081_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1138400
Cluster	P. falciparum: Cluster_29

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0910300	GCalpha	SSF81653: P-type ATPase, A domain superfamily, SSF56784:...	0.19	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004383	guanylate cyclase activity	TAS	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005887	integral component of plasma membrane	ISS	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006164	purine nucleotide biosynthetic process	None	Extended
BP	GO:0006182	cGMP biosynthetic process	TAS	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0007165	signal transduction	None	Extended
BP	GO:0007165	signal transduction	TAS	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009152	purine ribonucleotide biosynthetic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009187	cyclic nucleotide metabolic process	None	Extended
BP	GO:0009190	cyclic nucleotide biosynthetic process	IEA	Interproscan predictions
BP	GO:0009190	cyclic nucleotide biosynthetic process	IEA	PlasmoDB
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009260	ribonucleotide biosynthetic process	None	Extended
MF	GO:0009975	cyclase activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
CC	GO:0016021	integral component of membrane	ISM	PlasmoDB
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016849	phosphorus-oxygen lyase activity	IEA	Interproscan predictions
MF	GO:0016849	phosphorus-oxygen lyase activity	IEA	PlasmoDB
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0031226	intrinsic component of plasma membrane	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0035556	intracellular signal transduction	IEA	Interproscan predictions
BP	GO:0035556	intracellular signal transduction	IEA	PlasmoDB
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044459	plasma membrane part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046068	cGMP metabolic process	None	Extended
BP	GO:0046390	ribose phosphate biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0052652	cyclic purine nucleotide metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0072522	purine-containing compound biosynthetic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901137	carbohydrate derivative biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0003700	DNA-binding transcription factor activity	IEP	Predicted GO
MF	GO:0003774	motor activity	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0005267	potassium channel activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005516	calmodulin binding	IEP	Predicted GO
CC	GO:0005576	extracellular region	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
CC	GO:0005770	late endosome	IEP	Predicted GO
CC	GO:0005911	cell-cell junction	IEP	Predicted GO
CC	GO:0005923	bicellular tight junction	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006817	phosphate ion transport	IEP	Predicted GO
BP	GO:0006914	autophagy	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
BP	GO:0008154	actin polymerization or depolymerization	IEP	Predicted GO
BP	GO:0010638	positive regulation of organelle organization	IEP	Predicted GO
CC	GO:0015630	microtubule cytoskeleton	IEP	Predicted GO
BP	GO:0015698	inorganic anion transport	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
CC	GO:0016459	myosin complex	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
BP	GO:0030036	actin cytoskeleton organization	IEP	Predicted GO
CC	GO:0030054	cell junction	IEP	Predicted GO
BP	GO:0030838	positive regulation of actin filament polymerization	IEP	Predicted GO
BP	GO:0031334	positive regulation of protein complex assembly	IEP	Predicted GO
BP	GO:0032273	positive regulation of protein polymerization	IEP	Predicted GO
MF	GO:0042800	histone methyltransferase activity (H3-K4 specific)	IEP	Predicted GO
MF	GO:0043140	ATP-dependent 3'-5' DNA helicase activity	IEP	Predicted GO
MF	GO:0043142	single-stranded DNA-dependent ATPase activity	IEP	Predicted GO
MF	GO:0043565	sequence-specific DNA binding	IEP	Predicted GO
BP	GO:0044089	positive regulation of cellular component biogenesis	IEP	Predicted GO
BP	GO:0045010	actin nucleation	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
BP	GO:0051301	cell division	IEP	Predicted GO
BP	GO:0051495	positive regulation of cytoskeleton organization	IEP	Predicted GO
BP	GO:0061919	process utilizing autophagic mechanism	IEP	Predicted GO
CC	GO:0070160	tight junction	IEP	Predicted GO
MF	GO:0140110	transcription regulator activity	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
BP	GO:1902905	positive regulation of supramolecular fiber organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001054	A/G_cyclase	3164	3315
IPR001054	A/G_cyclase	3005	3075
IPR001054	A/G_cyclase	3965	4134
IPR032630	P_typ_ATPase_c	2058	2306

External Links

PlasmoDB	810941
PlasmoDB	PF11_0395

PF3D7_1138400 (GCalpha)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation