PF3D7_1206700 (EIF5)

Aliases : EIF5

Description : SSF75689: "Translation initiation factor IF2/IF5, zinc-binding", SSF48371: Armadillo-type fold, SSF100966: "Translation initiation factor IF2/IF5, N-terminal". Pfam domain(s): PF01873: Domain found in IF2B/IF5.

Gene families : OG_01_0000774 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000774_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1206700
Cluster	P. falciparum: Cluster_22

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	None	Extended
MF	GO:0003743	translation initiation factor activity	ISS	PlasmoDB
MF	GO:0003743	translation initiation factor activity	IEA	Interproscan predictions
MF	GO:0003743	translation initiation factor activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005488	binding	IEA	PlasmoDB
MF	GO:0005515	protein binding	IPI	PlasmoDB
MF	GO:0005515	protein binding	IEA	PlasmoDB
BP	GO:0006413	translational initiation	IEA	Interproscan predictions
BP	GO:0006413	translational initiation	IEA	PlasmoDB
BP	GO:0006417	regulation of translation	None	Extended
BP	GO:0006446	regulation of translational initiation	ISS	PlasmoDB
MF	GO:0008135	translation factor activity, RNA binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010608	posttranscriptional regulation of gene expression	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0032268	regulation of cellular protein metabolic process	None	Extended
BP	GO:0034248	regulation of cellular amide metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051246	regulation of protein metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000481	maturation of 5S rRNA	IEP	Predicted GO
MF	GO:0003727	single-stranded RNA binding	IEP	Predicted GO
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Predicted GO
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005087	Ran guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	IEP	Predicted GO
CC	GO:0005643	nuclear pore	IEP	Predicted GO
BP	GO:0006606	protein import into nucleus	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
MF	GO:0008143	poly(A) binding	IEP	Predicted GO
MF	GO:0008536	Ran GTPase binding	IEP	Predicted GO
MF	GO:0017016	Ras GTPase binding	IEP	Predicted GO
BP	GO:0017038	protein import	IEP	Predicted GO
BP	GO:0020027	hemoglobin metabolic process	IEP	Predicted GO
CC	GO:0030008	TRAPP complex	IEP	Predicted GO
MF	GO:0031267	small GTPase binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0034504	protein localization to nucleus	IEP	Predicted GO
CC	GO:0035770	ribonucleoprotein granule	IEP	Predicted GO
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	IEP	Predicted GO
BP	GO:0042540	hemoglobin catabolic process	IEP	Predicted GO
CC	GO:0043186	P granule	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0046540	U4/U6 x U5 tri-snRNP complex	IEP	Predicted GO
MF	GO:0051020	GTPase binding	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051170	import into nucleus	IEP	Predicted GO
MF	GO:0070001	aspartic-type peptidase activity	IEP	Predicted GO
MF	GO:0070717	poly-purine tract binding	IEP	Predicted GO
CC	GO:0097526	spliceosomal tri-snRNP complex	IEP	Predicted GO
CC	GO:0099023	tethering complex	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002735	Transl_init_fac_IF2/IF5	8	126

External Links

PlasmoDB	2277.t00068
PlasmoDB	811120
PlasmoDB	MAL12P1.67
PlasmoDB	PFL0335c

PF3D7_1206700 (EIF5)

Expression Profile

Co-expression Networks

Functional Annotation