PF3D7_1211700 (MCM5)


Aliases : MCM5

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase, SSF50249: "Nucleic acid-binding, OB-fold". Pfam domain(s): PF17855: MCM AAA-lid domain, PF17207: MCM OB domain, PF00493: MCM P-loop domain.


Gene families : OG_01_0002470 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002470_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_1211700
Cluster P. falciparum: Cluster_31

Target Alias Description ECC score Gene Family Method Actions
PBANKA_0610200 MCM5 SSF52540: P-loop containing nucleoside triphosphate... 0.05 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA Interproscan predictions
MF GO:0003677 DNA binding IEA PlasmoDB
MF GO:0005524 ATP binding ISM PlasmoDB
MF GO:0005524 ATP binding IEA Interproscan predictions
MF GO:0005524 ATP binding IEA PlasmoDB
BP GO:0006260 DNA replication IEA PlasmoDB
BP GO:0006270 DNA replication initiation IEA Interproscan predictions
BP GO:0006270 DNA replication initiation IEA PlasmoDB
CC GO:0042555 MCM complex ISS PlasmoDB
Type GO Term Name Evidence Source
BP GO:0000041 transition metal ion transport IEP Predicted GO
MF GO:0000234 phosphoethanolamine N-methyltransferase activity IEP Predicted GO
CC GO:0000502 proteasome complex IEP Predicted GO
CC GO:0000791 euchromatin IEP Predicted GO
BP GO:0002376 immune system process IEP Predicted GO
BP GO:0002377 immunoglobulin production IEP Predicted GO
BP GO:0002440 production of molecular mediator of immune response IEP Predicted GO
BP GO:0002682 regulation of immune system process IEP Predicted GO
MF GO:0003678 DNA helicase activity IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0004013 adenosylhomocysteinase activity IEP Predicted GO
MF GO:0004129 cytochrome-c oxidase activity IEP Predicted GO
MF GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity IEP Predicted GO
MF GO:0004372 glycine hydroxymethyltransferase activity IEP Predicted GO
MF GO:0004392 heme oxygenase (decyclizing) activity IEP Predicted GO
MF GO:0004478 methionine adenosyltransferase activity IEP Predicted GO
MF GO:0004774 succinate-CoA ligase activity IEP Predicted GO
MF GO:0004776 succinate-CoA ligase (GDP-forming) activity IEP Predicted GO
MF GO:0004791 thioredoxin-disulfide reductase activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005375 copper ion transmembrane transporter activity IEP Predicted GO
MF GO:0005388 calcium-transporting ATPase activity IEP Predicted GO
MF GO:0005509 calcium ion binding IEP Predicted GO
CC GO:0005672 transcription factor TFIIA complex IEP Predicted GO
CC GO:0005740 mitochondrial envelope IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
CC GO:0005784 Sec61 translocon complex IEP Predicted GO
CC GO:0005813 centrosome IEP Predicted GO
CC GO:0005814 centriole IEP Predicted GO
CC GO:0005815 microtubule organizing center IEP Predicted GO
CC GO:0005838 proteasome regulatory particle IEP Predicted GO
BP GO:0006099 tricarboxylic acid cycle IEP Predicted GO
BP GO:0006101 citrate metabolic process IEP Predicted GO
BP GO:0006104 succinyl-CoA metabolic process IEP Predicted GO
BP GO:0006108 malate metabolic process IEP Predicted GO
BP GO:0006116 NADH oxidation IEP Predicted GO
BP GO:0006127 glycerophosphate shuttle IEP Predicted GO
BP GO:0006333 chromatin assembly or disassembly IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006511 ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0006545 glycine biosynthetic process IEP Predicted GO
BP GO:0006556 S-adenosylmethionine biosynthetic process IEP Predicted GO
BP GO:0006563 L-serine metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006734 NADH metabolic process IEP Predicted GO
BP GO:0006812 cation transport IEP Predicted GO
BP GO:0006816 calcium ion transport IEP Predicted GO
BP GO:0006825 copper ion transport IEP Predicted GO
BP GO:0006833 water transport IEP Predicted GO
BP GO:0006996 organelle organization IEP Predicted GO
BP GO:0007010 cytoskeleton organization IEP Predicted GO
BP GO:0007029 endoplasmic reticulum organization IEP Predicted GO
BP GO:0007051 spindle organization IEP Predicted GO
BP GO:0007052 mitotic spindle organization IEP Predicted GO
MF GO:0008121 ubiquinol-cytochrome-c reductase activity IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
MF GO:0008324 cation transmembrane transporter activity IEP Predicted GO
MF GO:0008519 ammonium transmembrane transporter activity IEP Predicted GO
CC GO:0008540 proteasome regulatory particle, base subcomplex IEP Predicted GO
MF GO:0009055 electron transfer activity IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009057 macromolecule catabolic process IEP Predicted GO
BP GO:0009070 serine family amino acid biosynthetic process IEP Predicted GO
CC GO:0009331 glycerol-3-phosphate dehydrogenase complex IEP Predicted GO
CC GO:0009986 cell surface IEP Predicted GO
MF GO:0015002 heme-copper terminal oxidase activity IEP Predicted GO
BP GO:0015074 DNA integration IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015085 calcium ion transmembrane transporter activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
BP GO:0015791 polyol transport IEP Predicted GO
BP GO:0015850 organic hydroxy compound transport IEP Predicted GO
CC GO:0016021 integral component of membrane IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
MF GO:0016209 antioxidant activity IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016675 oxidoreductase activity, acting on a heme group of donors IEP Predicted GO
MF GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor IEP Predicted GO
MF GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors IEP Predicted GO
MF GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor IEP Predicted GO
MF GO:0016742 hydroxymethyl-, formyl- and related transferase activity IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016801 hydrolase activity, acting on ether bonds IEP Predicted GO
MF GO:0016802 trialkylsulfonium hydrolase activity IEP Predicted GO
MF GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor IEP Predicted GO
BP GO:0016999 antibiotic metabolic process IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0019264 glycine biosynthetic process from serine IEP Predicted GO
BP GO:0019674 NAD metabolic process IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
BP GO:0019941 modification-dependent protein catabolic process IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0022890 inorganic cation transmembrane transporter activity IEP Predicted GO
BP GO:0030001 metal ion transport IEP Predicted GO
CC GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
CC GO:0031224 intrinsic component of membrane IEP Predicted GO
CC GO:0031965 nuclear membrane IEP Predicted GO
CC GO:0031982 vesicle IEP Predicted GO
BP GO:0032780 negative regulation of ATPase activity IEP Predicted GO
BP GO:0033044 regulation of chromosome organization IEP Predicted GO
BP GO:0034308 primary alcohol metabolic process IEP Predicted GO
BP GO:0035434 copper ion transmembrane transport IEP Predicted GO
BP GO:0035999 tetrahydrofolate interconversion IEP Predicted GO
BP GO:0042044 fluid transport IEP Predicted GO
BP GO:0042136 neurotransmitter biosynthetic process IEP Predicted GO
BP GO:0042176 regulation of protein catabolic process IEP Predicted GO
MF GO:0042393 histone binding IEP Predicted GO
CC GO:0042709 succinate-CoA ligase complex IEP Predicted GO
BP GO:0043086 negative regulation of catalytic activity IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043230 extracellular organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0043248 proteasome assembly IEP Predicted GO
BP GO:0043462 regulation of ATPase activity IEP Predicted GO
BP GO:0043632 modification-dependent macromolecule catabolic process IEP Predicted GO
BP GO:0044092 negative regulation of molecular function IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044265 cellular macromolecule catabolic process IEP Predicted GO
CC GO:0044421 extracellular region part IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
CC GO:0044429 mitochondrial part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044450 microtubule organizing center part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
CC GO:0045244 succinate-CoA ligase complex (GDP-forming) IEP Predicted GO
BP GO:0045454 cell redox homeostasis IEP Predicted GO
BP GO:0046416 D-amino acid metabolic process IEP Predicted GO
BP GO:0046500 S-adenosylmethionine metabolic process IEP Predicted GO
BP GO:0046653 tetrahydrofolate metabolic process IEP Predicted GO
CC GO:0046658 anchored component of plasma membrane IEP Predicted GO
MF GO:0046873 metal ion transmembrane transporter activity IEP Predicted GO
MF GO:0046915 transition metal ion transmembrane transporter activity IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
BP GO:0050776 regulation of immune response IEP Predicted GO
BP GO:0050790 regulation of catalytic activity IEP Predicted GO
BP GO:0051095 regulation of helicase activity IEP Predicted GO
BP GO:0051097 negative regulation of helicase activity IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051336 regulation of hydrolase activity IEP Predicted GO
BP GO:0051346 negative regulation of hydrolase activity IEP Predicted GO
BP GO:0051475 glucosylglycerol transport IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0065008 regulation of biological quality IEP Predicted GO
BP GO:0065009 regulation of molecular function IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0070178 D-serine metabolic process IEP Predicted GO
BP GO:0070682 proteasome regulatory particle assembly IEP Predicted GO
CC GO:0071256 translocon complex IEP Predicted GO
CC GO:0071782 endoplasmic reticulum tubular network IEP Predicted GO
BP GO:0071786 endoplasmic reticulum tubular network organization IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0072350 tricarboxylic acid metabolic process IEP Predicted GO
CC GO:0098798 mitochondrial protein complex IEP Predicted GO
CC GO:0098827 endoplasmic reticulum subcompartment IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901565 organonitrogen compound catabolic process IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
CC GO:1902494 catalytic complex IEP Predicted GO
BP GO:1902850 microtubule cytoskeleton organization involved in mitosis IEP Predicted GO
CC GO:1903561 extracellular vesicle IEP Predicted GO
CC GO:1905368 peptidase complex IEP Predicted GO
CC GO:1905369 endopeptidase complex IEP Predicted GO
BP GO:1905462 regulation of DNA duplex unwinding IEP Predicted GO
BP GO:1905463 negative regulation of DNA duplex unwinding IEP Predicted GO
BP GO:1905774 regulation of DNA helicase activity IEP Predicted GO
BP GO:1905775 negative regulation of DNA helicase activity IEP Predicted GO
CC GO:1990204 oxidoreductase complex IEP Predicted GO
BP GO:2001251 negative regulation of chromosome organization IEP Predicted GO
InterPro domains Description Start Stop
IPR033762 MCM_OB 165 312
IPR001208 MCM_dom 354 574
PlasmoDB 2277.t00117
PlasmoDB 811169
PlasmoDB MAL12P1.116
PlasmoDB PFL0580w