PF3D7_1215000 (Trx-Px2)

Aliases : Trx-Px2

Description : SSF52833: Thioredoxin-like superfamily. Pfam domain(s): PF10417: C-terminal domain of 1-Cys peroxiredoxin, PF00578: AhpC/TSA family.

Gene families : OG_01_0000088 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000088_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1215000
Cluster	P. falciparum: Cluster_1

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1302800	TPx1	SSF52833: Thioredoxin-like superfamily. Pfam domain(s):...	0.04	Orthofinderv1.1.8
PBANKA_1430800	Trx-Px2	SSF52833: Thioredoxin-like superfamily. Pfam domain(s):...	0.07	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004601	peroxidase activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	IDA	PlasmoDB
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006979	response to oxidative stress	IDA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008379	thioredoxin peroxidase activity	IDA	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016209	antioxidant activity	IEA	Interproscan predictions
MF	GO:0016209	antioxidant activity	IEA	PlasmoDB
MF	GO:0016491	oxidoreductase activity	IEA	Interproscan predictions
MF	GO:0016491	oxidoreductase activity	IEA	PlasmoDB
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	None	Extended
BP	GO:0019725	cellular homeostasis	None	Extended
BP	GO:0042592	homeostatic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045454	cell redox homeostasis	IEA	PlasmoDB
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
MF	GO:0051920	peroxiredoxin activity	IEA	Interproscan predictions
MF	GO:0051920	peroxiredoxin activity	IEA	PlasmoDB
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan predictions
BP	GO:0055114	oxidation-reduction process	IEA	PlasmoDB
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0003756	protein disulfide isomerase activity	IEP	Predicted GO
MF	GO:0004129	cytochrome-c oxidase activity	IEP	Predicted GO
MF	GO:0004633	phosphopantothenoylcysteine decarboxylase activity	IEP	Predicted GO
MF	GO:0005507	copper ion binding	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
CC	GO:0005740	mitochondrial envelope	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
CC	GO:0005750	mitochondrial respiratory chain complex III	IEP	Predicted GO
CC	GO:0005762	mitochondrial large ribosomal subunit	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005813	centrosome	IEP	Predicted GO
CC	GO:0005815	microtubule organizing center	IEP	Predicted GO
CC	GO:0005884	actin filament	IEP	Predicted GO
BP	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	IEP	Predicted GO
BP	GO:0007034	vacuolar transport	IEP	Predicted GO
MF	GO:0008121	ubiquinol-cytochrome-c reductase activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
MF	GO:0015002	heme-copper terminal oxidase activity	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0016018	cyclosporin A binding	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
BP	GO:0016482	cytosolic transport	IEP	Predicted GO
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	IEP	Predicted GO
MF	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
CC	GO:0020009	microneme	IEP	Predicted GO
BP	GO:0022904	respiratory electron transport chain	IEP	Predicted GO
CC	GO:0030904	retromer complex	IEP	Predicted GO
CC	GO:0031090	organelle membrane	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
CC	GO:0031967	organelle envelope	IEP	Predicted GO
CC	GO:0031975	envelope	IEP	Predicted GO
BP	GO:0042147	retrograde transport, endosome to Golgi	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0045275	respiratory chain complex III	IEP	Predicted GO
CC	GO:0070069	cytochrome complex	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
CC	GO:0098798	mitochondrial protein complex	IEP	Predicted GO
CC	GO:0098803	respiratory chain complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR019479	Peroxiredoxin_C	177	203
IPR000866	AhpC/TSA	23	155

External Links

PlasmoDB	2277.t00146
PlasmoDB	811198
PlasmoDB	MAL12P1.145
PlasmoDB	PFL0725w

PF3D7_1215000 (Trx-Px2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation