PF3D7_1224500 (ASF1)

Aliases : ASF1

Description : SSF101546: Histone chaperone ASF1-like superfamily. Pfam domain(s): PF04729: ASF1 like histone chaperone.

Gene families : OG_01_0002160 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002160_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1224500
Cluster	P. falciparum: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1439400	ASF1	SSF101546: Histone chaperone ASF1-like superfamily. Pfam...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003682	chromatin binding	ISS	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan predictions
CC	GO:0005634	nucleus	IEA	PlasmoDB
BP	GO:0006325	chromatin organization	None	Extended
BP	GO:0006333	chromatin assembly or disassembly	IEA	Interproscan predictions
BP	GO:0006333	chromatin assembly or disassembly	IEA	PlasmoDB
BP	GO:0006334	nucleosome assembly	IEA	PlasmoDB
BP	GO:0006337	nucleosome disassembly	IEA	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006473	protein acetylation	None	Extended
BP	GO:0006475	internal protein amino acid acetylation	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0016458	gene silencing	ISS	PlasmoDB
BP	GO:0016569	covalent chromatin modification	None	Extended
BP	GO:0016570	histone modification	None	Extended
BP	GO:0016573	histone acetylation	IEA	PlasmoDB
BP	GO:0018193	peptidyl-amino acid modification	None	Extended
BP	GO:0018205	peptidyl-lysine modification	None	Extended
BP	GO:0018393	internal peptidyl-lysine acetylation	None	Extended
BP	GO:0018394	peptidyl-lysine acetylation	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0022411	cellular component disassembly	None	Extended
BP	GO:0022607	cellular component assembly	None	Extended
BP	GO:0031497	chromatin assembly	ISS	PlasmoDB
BP	GO:0032984	protein-containing complex disassembly	None	Extended
BP	GO:0032986	protein-DNA complex disassembly	None	Extended
BP	GO:0034622	cellular protein-containing complex assembly	None	Extended
BP	GO:0034728	nucleosome organization	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0042393	histone binding	IEA	PlasmoDB
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043543	protein acylation	None	Extended
BP	GO:0043933	protein-containing complex subunit organization	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
MF	GO:0051082	unfolded protein binding	ISS	PlasmoDB
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065003	protein-containing complex assembly	None	Extended
BP	GO:0065004	protein-DNA complex assembly	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071824	protein-DNA complex subunit organization	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000278	mitotic cell cycle	IEP	Predicted GO
CC	GO:0000796	condensin complex	IEP	Predicted GO
MF	GO:0003785	actin monomer binding	IEP	Predicted GO
MF	GO:0003909	DNA ligase activity	IEP	Predicted GO
MF	GO:0003911	DNA ligase (NAD+) activity	IEP	Predicted GO
MF	GO:0004057	arginyltransferase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	IEP	Predicted GO
MF	GO:0004368	glycerol-3-phosphate dehydrogenase (quinone) activity	IEP	Predicted GO
MF	GO:0004550	nucleoside diphosphate kinase activity	IEP	Predicted GO
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Predicted GO
MF	GO:0004774	succinate-CoA ligase activity	IEP	Predicted GO
MF	GO:0004775	succinate-CoA ligase (ADP-forming) activity	IEP	Predicted GO
MF	GO:0005046	KDEL sequence binding	IEP	Predicted GO
MF	GO:0005375	copper ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
CC	GO:0005784	Sec61 translocon complex	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
CC	GO:0005955	calcineurin complex	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006104	succinyl-CoA metabolic process	IEP	Predicted GO
BP	GO:0006116	NADH oxidation	IEP	Predicted GO
BP	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	IEP	Predicted GO
BP	GO:0006127	glycerophosphate shuttle	IEP	Predicted GO
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006323	DNA packaging	IEP	Predicted GO
BP	GO:0006410	obsolete transcription, RNA-dependent	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006621	protein retention in ER lumen	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006734	NADH metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006790	sulfur compound metabolic process	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
BP	GO:0007076	mitotic chromosome condensation	IEP	Predicted GO
MF	GO:0008121	ubiquinol-cytochrome-c reductase activity	IEP	Predicted GO
MF	GO:0008179	adenylate cyclase binding	IEP	Predicted GO
MF	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	IEP	Predicted GO
MF	GO:0008914	leucyltransferase activity	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Predicted GO
CC	GO:0009331	glycerol-3-phosphate dehydrogenase complex	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
BP	GO:0016598	protein arginylation	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	IEP	Predicted GO
MF	GO:0016755	transferase activity, transferring amino-acyl groups	IEP	Predicted GO
MF	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	IEP	Predicted GO
BP	GO:0018143	nucleic acid-protein covalent cross-linking	IEP	Predicted GO
BP	GO:0018144	RNA-protein covalent cross-linking	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019674	NAD metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
CC	GO:0019774	proteasome core complex, beta-subunit complex	IEP	Predicted GO
MF	GO:0019888	protein phosphatase regulator activity	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
MF	GO:0030234	enzyme regulator activity	IEP	Predicted GO
BP	GO:0030261	chromosome condensation	IEP	Predicted GO
MF	GO:0030337	DNA polymerase processivity factor activity	IEP	Predicted GO
MF	GO:0031079	obsolete picornain 3C activity	IEP	Predicted GO
CC	GO:0031225	anchored component of membrane	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
BP	GO:0032507	maintenance of protein location in cell	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
BP	GO:0034308	primary alcohol metabolic process	IEP	Predicted GO
BP	GO:0035434	copper ion transmembrane transport	IEP	Predicted GO
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
CC	GO:0043626	PCNA complex	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044796	DNA polymerase processivity factor complex	IEP	Predicted GO
BP	GO:0045185	maintenance of protein location	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
CC	GO:0046658	anchored component of plasma membrane	IEP	Predicted GO
MF	GO:0046923	ER retention sequence binding	IEP	Predicted GO
BP	GO:0046939	nucleotide phosphorylation	IEP	Predicted GO
MF	GO:0048306	calcium-dependent protein binding	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
BP	GO:0050801	ion homeostasis	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0051651	maintenance of location in cell	IEP	Predicted GO
BP	GO:0055074	calcium ion homeostasis	IEP	Predicted GO
BP	GO:0055080	cation homeostasis	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
BP	GO:0071103	DNA conformation change	IEP	Predicted GO
CC	GO:0071256	translocon complex	IEP	Predicted GO
BP	GO:0072507	divalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072595	maintenance of protein localization in organelle	IEP	Predicted GO
BP	GO:0098655	cation transmembrane transport	IEP	Predicted GO
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Predicted GO
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Predicted GO
BP	GO:0098771	inorganic ion homeostasis	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
CC	GO:1990204	oxidoreductase complex	IEP	Predicted GO
CC	GO:1990229	iron-sulfur cluster assembly complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006818	ASF1-like	1	157

External Links

PlasmoDB	2277.t00236
PlasmoDB	811288
PlasmoDB	MAL12P1.236
PlasmoDB	PFL1180w

PF3D7_1224500 (ASF1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation