PF3D7_1239700 (FTSH1)

Aliases : FTSH1

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase, SSF140990: Peptidase M41-like. Pfam domain(s): PF17862: AAA+ lid domain, PF01434: Peptidase family M41, PF00004: ATPase family associated with various cellular activities (AAA).

Gene families : OG_01_0003301 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0003301_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1239700
Cluster	P. falciparum: Cluster_17

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1454100	FTSH1	SSF52540: P-loop containing nucleoside triphosphate...	0.02	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	None	Extended
MF	GO:0004176	ATP-dependent peptidase activity	IDA	PlasmoDB
MF	GO:0004222	metalloendopeptidase activity	IDA	PlasmoDB
MF	GO:0004222	metalloendopeptidase activity	IEA	Interproscan predictions
MF	GO:0004222	metalloendopeptidase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IDA	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	IDA	PlasmoDB
BP	GO:0006508	proteolysis	IDA	PlasmoDB
BP	GO:0006508	proteolysis	IEA	Interproscan predictions
BP	GO:0006508	proteolysis	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008237	metallopeptidase activity	None	Extended
CC	GO:0009536	plastid	None	Extended
CC	GO:0016020	membrane	IEA	PlasmoDB
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042493	response to drug	IMP	PlasmoDB
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	IEP	Predicted GO
MF	GO:0000104	succinate dehydrogenase activity	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
BP	GO:0002376	immune system process	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002682	regulation of immune system process	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0003924	GTPase activity	IEP	Predicted GO
MF	GO:0004402	histone acetyltransferase activity	IEP	Predicted GO
MF	GO:0004467	long-chain fatty acid-CoA ligase activity	IEP	Predicted GO
MF	GO:0005047	signal recognition particle binding	IEP	Predicted GO
MF	GO:0005507	copper ion binding	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005785	signal recognition particle receptor complex	IEP	Predicted GO
CC	GO:0005813	centrosome	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006612	protein targeting to membrane	IEP	Predicted GO
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006816	calcium ion transport	IEP	Predicted GO
BP	GO:0006825	copper ion transport	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
MF	GO:0008080	N-acetyltransferase activity	IEP	Predicted GO
MF	GO:0008177	succinate dehydrogenase (ubiquinone) activity	IEP	Predicted GO
MF	GO:0008273	calcium, potassium:sodium antiporter activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
MF	GO:0015079	potassium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015085	calcium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015297	antiporter activity	IEP	Predicted GO
MF	GO:0015298	solute:cation antiporter activity	IEP	Predicted GO
MF	GO:0015299	solute:proton antiporter activity	IEP	Predicted GO
MF	GO:0015368	calcium:cation antiporter activity	IEP	Predicted GO
MF	GO:0015369	calcium:proton antiporter activity	IEP	Predicted GO
MF	GO:0015491	cation:cation antiporter activity	IEP	Predicted GO
MF	GO:0015645	fatty acid ligase activity	IEP	Predicted GO
MF	GO:0016208	AMP binding	IEP	Predicted GO
MF	GO:0016407	acetyltransferase activity	IEP	Predicted GO
MF	GO:0016410	N-acyltransferase activity	IEP	Predicted GO
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Predicted GO
MF	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0022411	cellular component disassembly	IEP	Predicted GO
MF	GO:0022821	potassium ion antiporter activity	IEP	Predicted GO
BP	GO:0022900	electron transport chain	IEP	Predicted GO
BP	GO:0030001	metal ion transport	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0032790	ribosome disassembly	IEP	Predicted GO
BP	GO:0032984	protein-containing complex disassembly	IEP	Predicted GO
BP	GO:0032988	ribonucleoprotein complex disassembly	IEP	Predicted GO
MF	GO:0034212	peptide N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0042026	protein refolding	IEP	Predicted GO
MF	GO:0042393	histone binding	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
BP	GO:0043248	proteasome assembly	IEP	Predicted GO
CC	GO:0043264	extracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
BP	GO:0045047	protein targeting to ER	IEP	Predicted GO
CC	GO:0045257	succinate dehydrogenase complex (ubiquinone)	IEP	Predicted GO
CC	GO:0045281	succinate dehydrogenase complex	IEP	Predicted GO
CC	GO:0045283	fumarate reductase complex	IEP	Predicted GO
MF	GO:0050660	flavin adenine dinucleotide binding	IEP	Predicted GO
BP	GO:0050776	regulation of immune response	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
MF	GO:0051139	metal ion:proton antiporter activity	IEP	Predicted GO
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0070838	divalent metal ion transport	IEP	Predicted GO
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0072511	divalent inorganic cation transport	IEP	Predicted GO
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0072657	protein localization to membrane	IEP	Predicted GO
CC	GO:0085026	tubovesicular membrane network	IEP	Predicted GO
BP	GO:0090150	establishment of protein localization to membrane	IEP	Predicted GO
CC	GO:0098803	respiratory chain complex	IEP	Predicted GO
MF	GO:0099516	ion antiporter activity	IEP	Predicted GO
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Predicted GO
BP	GO:1903008	organelle disassembly	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000642	Peptidase_M41	404	587
IPR003959	ATPase_AAA_core	185	320

External Links

PlasmoDB	2277.t00385
PlasmoDB	811437
PlasmoDB	MAL12P1.383
PlasmoDB	PFL1925w

PF3D7_1239700 (FTSH1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation