PF3D7_1245100 (KLP8)

Aliases : KLP8

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF00225: Kinesin motor domain.

Gene families : OG_01_0002228 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002228_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1245100
Cluster	P. falciparum: Cluster_32

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003774	motor activity	None	Extended
MF	GO:0003774	motor activity	ISS	PlasmoDB
MF	GO:0003777	microtubule motor activity	IEA	Interproscan predictions
MF	GO:0003777	microtubule motor activity	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005871	kinesin complex	ISS	PlasmoDB
CC	GO:0005875	microtubule associated complex	None	Extended
BP	GO:0006928	movement of cell or subcellular component	None	Extended
BP	GO:0007017	microtubule-based process	None	Extended
BP	GO:0007018	microtubule-based movement	ISS	PlasmoDB
BP	GO:0007018	microtubule-based movement	IEA	Interproscan predictions
BP	GO:0007018	microtubule-based movement	IEA	PlasmoDB
MF	GO:0008017	microtubule binding	IEA	Interproscan predictions
MF	GO:0008017	microtubule binding	IEA	PlasmoDB
MF	GO:0008092	cytoskeletal protein binding	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0015631	tubulin binding	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044430	cytoskeletal part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000781	chromosome, telomeric region	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0004003	ATP-dependent DNA helicase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
BP	GO:0006310	DNA recombination	IEP	Predicted GO
BP	GO:0007049	cell cycle	IEP	Predicted GO
BP	GO:0007059	chromosome segregation	IEP	Predicted GO
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Predicted GO
BP	GO:0032392	DNA geometric change	IEP	Predicted GO
BP	GO:0032508	DNA duplex unwinding	IEP	Predicted GO
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Predicted GO
MF	GO:0043140	ATP-dependent 3'-5' DNA helicase activity	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0071103	DNA conformation change	IEP	Predicted GO
CC	GO:0098687	chromosomal region	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001752	Kinesin_motor_dom	48	371

External Links

PlasmoDB	2277.t00433
PlasmoDB	811485
PlasmoDB	MAL12P1.431
PlasmoDB	PFL2165w

PF3D7_1245100 (KLP8)

Expression Profile

Co-expression Networks

Functional Annotation