PF3D7_1248000

Description : SSF53032: "tRNA intron endonuclease, catalytic domain-like superfamily". Pfam domain(s): PF01974: "tRNA intron endonuclease, catalytic C-terminal domain".

Gene families : OG_01_0004569 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0004569_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1248000
Cluster	P. falciparum: Cluster_45

Type	GO Term	Name	Evidence	Source
MF	GO:0000213	tRNA-intron endonuclease activity	ISM	PlasmoDB
MF	GO:0000213	tRNA-intron endonuclease activity	IEA	Interproscan predictions
MF	GO:0000213	tRNA-intron endonuclease activity	IEA	PlasmoDB
CC	GO:0000214	tRNA-intron endonuclease complex	IEA	PlasmoDB
BP	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	None	Extended
MF	GO:0004521	endoribonuclease activity	None	Extended
MF	GO:0004540	ribonuclease activity	None	Extended
MF	GO:0004549	tRNA-specific ribonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	ISM	PlasmoDB
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	IEA	Interproscan predictions
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	IEA	PlasmoDB
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008033	tRNA processing	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008380	RNA splicing	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters	None	Extended
MF	GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0034470	ncRNA processing	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044428	nuclear part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1902555	endoribonuclease complex	None	Extended
CC	GO:1905348	endonuclease complex	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
BP	GO:0000096	sulfur amino acid metabolic process	IEP	Predicted GO
CC	GO:0000164	protein phosphatase type 1 complex	IEP	Predicted GO
MF	GO:0004425	indole-3-glycerol-phosphate synthase activity	IEP	Predicted GO
MF	GO:0004857	enzyme inhibitor activity	IEP	Predicted GO
MF	GO:0004864	protein phosphatase inhibitor activity	IEP	Predicted GO
MF	GO:0004865	protein serine/threonine phosphatase inhibitor activity	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006505	GPI anchor metabolic process	IEP	Predicted GO
BP	GO:0006506	GPI anchor biosynthetic process	IEP	Predicted GO
BP	GO:0006534	cysteine metabolic process	IEP	Predicted GO
BP	GO:0006643	membrane lipid metabolic process	IEP	Predicted GO
BP	GO:0006661	phosphatidylinositol biosynthetic process	IEP	Predicted GO
BP	GO:0006664	glycolipid metabolic process	IEP	Predicted GO
BP	GO:0006766	vitamin metabolic process	IEP	Predicted GO
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Predicted GO
BP	GO:0006768	biotin metabolic process	IEP	Predicted GO
BP	GO:0006790	sulfur compound metabolic process	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
MF	GO:0008408	3'-5' exonuclease activity	IEP	Predicted GO
BP	GO:0009069	serine family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009102	biotin biosynthetic process	IEP	Predicted GO
BP	GO:0009110	vitamin biosynthetic process	IEP	Predicted GO
BP	GO:0009247	glycolipid biosynthetic process	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
MF	GO:0016758	transferase activity, transferring hexosyl groups	IEP	Predicted GO
MF	GO:0016782	transferase activity, transferring sulfur-containing groups	IEP	Predicted GO
MF	GO:0016783	sulfurtransferase activity	IEP	Predicted GO
MF	GO:0016830	carbon-carbon lyase activity	IEP	Predicted GO
MF	GO:0016831	carboxy-lyase activity	IEP	Predicted GO
MF	GO:0019208	phosphatase regulator activity	IEP	Predicted GO
MF	GO:0019212	phosphatase inhibitor activity	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
MF	GO:0019888	protein phosphatase regulator activity	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
MF	GO:0031071	cysteine desulfurase activity	IEP	Predicted GO
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Predicted GO
BP	GO:0046467	membrane lipid biosynthetic process	IEP	Predicted GO
BP	GO:0046474	glycerophospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0046488	phosphatidylinositol metabolic process	IEP	Predicted GO
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Predicted GO
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO
BP	GO:1903509	liposaccharide metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006677	tRNA_intron_Endonuc_cat-like	129	199

External Links

PlasmoDB	2277.t00460
PlasmoDB	811512
PlasmoDB	MAL12P1.459
PlasmoDB	PFL2300w

PF3D7_1248000

Expression Profile

Co-expression Networks

Functional Annotation