PF3D7_1249900 (KsgA2)

Aliases : KsgA2

Description : SSF53335: S-adenosyl-L-methionine-dependent methyltransferase. Pfam domain(s): PF00398: Ribosomal RNA adenine dimethylase.

Gene families : OG_01_0002245 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002245_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1249900
Cluster	P. falciparum: Cluster_48

Type	GO Term	Name	Evidence	Source
BP	GO:0000154	rRNA modification	IEA	PlasmoDB
MF	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	ISS	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006364	rRNA processing	IEA	PlasmoDB
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008170	N-methyltransferase activity	None	Extended
MF	GO:0008173	RNA methyltransferase activity	None	Extended
MF	GO:0008649	rRNA methyltransferase activity	ISS	PlasmoDB
MF	GO:0008649	rRNA methyltransferase activity	IEA	PlasmoDB
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	None	Extended
BP	GO:0009451	RNA modification	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016072	rRNA metabolic process	None	Extended
MF	GO:0016433	rRNA (adenine) methyltransferase activity	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
CC	GO:0020011	apicoplast	RCA	PlasmoDB
BP	GO:0034470	ncRNA processing	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140102	catalytic activity, acting on a rRNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003697	single-stranded DNA binding	IEP	Predicted GO
MF	GO:0003743	translation initiation factor activity	IEP	Predicted GO
MF	GO:0004311	farnesyltranstransferase activity	IEP	Predicted GO
MF	GO:0004448	isocitrate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004450	isocitrate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004462	lactoylglutathione lyase activity	IEP	Predicted GO
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Predicted GO
MF	GO:0004828	serine-tRNA ligase activity	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005746	mitochondrial respirasome	IEP	Predicted GO
BP	GO:0006102	isocitrate metabolic process	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006413	translational initiation	IEP	Predicted GO
BP	GO:0006434	seryl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006627	protein processing involved in protein targeting to mitochondrion	IEP	Predicted GO
BP	GO:0006749	glutathione metabolic process	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008495	protoheme IX farnesyltransferase activity	IEP	Predicted GO
BP	GO:0008535	respiratory chain complex IV assembly	IEP	Predicted GO
BP	GO:0009070	serine family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0016259	selenocysteine metabolic process	IEP	Predicted GO
BP	GO:0016260	selenocysteine biosynthetic process	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016846	carbon-sulfur lyase activity	IEP	Predicted GO
BP	GO:0017004	cytochrome complex assembly	IEP	Predicted GO
BP	GO:0017062	respiratory chain complex III assembly	IEP	Predicted GO
CC	GO:0017087	mitochondrial processing peptidase complex	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
BP	GO:0031497	chromatin assembly	IEP	Predicted GO
BP	GO:0033108	mitochondrial respiratory chain complex assembly	IEP	Predicted GO
BP	GO:0034551	mitochondrial respiratory chain complex III assembly	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0034982	mitochondrial protein processing	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
BP	GO:0048033	heme o metabolic process	IEP	Predicted GO
BP	GO:0048034	heme O biosynthetic process	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051131	chaperone-mediated protein complex assembly	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
CC	GO:0070469	respirasome	IEP	Predicted GO
CC	GO:0098798	mitochondrial protein complex	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001737	KsgA/Erm	387	596

External Links

PlasmoDB	2277.t00479
PlasmoDB	811531
PlasmoDB	MAL12P1.477
PlasmoDB	PFL2395c

PF3D7_1249900 (KsgA2)

Expression Profile

Co-expression Networks

Functional Annotation