PF3D7_1303500 (NHE)

Aliases : NHE

Description : No superfamily available. Pfam domain(s): PF00999: Sodium/hydrogen exchanger family.

Gene families : OG_01_0000400 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000400_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1303500
Cluster	P. falciparum: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1402000	No alias	No superfamily available. Pfam domain(s): PF00999:...	0.16	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005215	transporter activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006811	ion transport	None	Extended
BP	GO:0006812	cation transport	IEA	Interproscan predictions
BP	GO:0006812	cation transport	IEA	PlasmoDB
BP	GO:0006814	sodium ion transport	IDA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008324	cation transmembrane transporter activity	None	Extended
MF	GO:0015075	ion transmembrane transporter activity	None	Extended
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	None	Extended
MF	GO:0015078	proton transmembrane transporter activity	None	Extended
MF	GO:0015291	secondary active transmembrane transporter activity	None	Extended
MF	GO:0015297	antiporter activity	None	Extended
MF	GO:0015298	solute:cation antiporter activity	None	Extended
MF	GO:0015299	solute:proton antiporter activity	IDA	PlasmoDB
MF	GO:0015299	solute:proton antiporter activity	IEA	Interproscan predictions
MF	GO:0015299	solute:proton antiporter activity	IEA	PlasmoDB
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	None	Extended
BP	GO:0015672	monovalent inorganic cation transport	None	Extended
CC	GO:0016021	integral component of membrane	ISM	PlasmoDB
CC	GO:0016021	integral component of membrane	IEA	Interproscan predictions
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0022890	inorganic cation transmembrane transporter activity	None	Extended
BP	GO:0030001	metal ion transport	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042493	response to drug	IDA	PlasmoDB
CC	GO:0044425	membrane part	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	Interproscan predictions
BP	GO:0055085	transmembrane transport	IEA	PlasmoDB

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Type	GO Term	Name	Evidence	Source
MF	GO:0004016	adenylate cyclase activity	IEP	Predicted GO
MF	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity	IEP	Predicted GO
MF	GO:0004143	diacylglycerol kinase activity	IEP	Predicted GO
MF	GO:0004252	serine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004383	guanylate cyclase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005905	clathrin-coated pit	IEP	Predicted GO
CC	GO:0005952	cAMP-dependent protein kinase complex	IEP	Predicted GO
BP	GO:0006182	cGMP biosynthetic process	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006892	post-Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0006895	Golgi to endosome transport	IEP	Predicted GO
BP	GO:0006915	apoptotic process	IEP	Predicted GO
BP	GO:0007165	signal transduction	IEP	Predicted GO
BP	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	IEP	Predicted GO
BP	GO:0008219	cell death	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
BP	GO:0009268	response to pH	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
BP	GO:0012501	programmed cell death	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
CC	GO:0016459	myosin complex	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
CC	GO:0020008	rhoptry	IEP	Predicted GO
BP	GO:0030260	entry into host cell	IEP	Predicted GO
CC	GO:0031225	anchored component of membrane	IEP	Predicted GO
CC	GO:0031226	intrinsic component of plasma membrane	IEP	Predicted GO
BP	GO:0031400	negative regulation of protein modification process	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0033016	rhoptry membrane	IEP	Predicted GO
BP	GO:0035556	intracellular signal transduction	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
BP	GO:0044409	entry into host	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
CC	GO:0044459	plasma membrane part	IEP	Predicted GO
CC	GO:0045121	membrane raft	IEP	Predicted GO
BP	GO:0046068	cGMP metabolic process	IEP	Predicted GO
CC	GO:0046658	anchored component of plasma membrane	IEP	Predicted GO
MF	GO:0046812	host cell surface binding	IEP	Predicted GO
BP	GO:0046839	phospholipid dephosphorylation	IEP	Predicted GO
BP	GO:0046856	phosphatidylinositol dephosphorylation	IEP	Predicted GO
BP	GO:0050746	regulation of lipoprotein metabolic process	IEP	Predicted GO
BP	GO:0050748	negative regulation of lipoprotein metabolic process	IEP	Predicted GO
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051828	entry into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0052652	cyclic purine nucleotide metabolic process	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
CC	GO:0098589	membrane region	IEP	Predicted GO
CC	GO:0098857	membrane microdomain	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
BP	GO:1903059	regulation of protein lipidation	IEP	Predicted GO
BP	GO:1903060	negative regulation of protein lipidation	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
CC	GO:1990225	rhoptry neck	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006153	Cation/H_exchanger	245	649

External Links

PlasmoDB	813998
PlasmoDB	PF13_0019

PF3D7_1303500 (NHE)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation