PF3D7_1304100 (LigI)

Aliases : LigI

Description : SSF50249: "Nucleic acid-binding, OB-fold", SSF117018: "DNA ligase, ATP-dependent, N-terminal domain superfamily", SSF56091: No description available. Pfam domain(s): PF04675: DNA ligase N terminus, PF01068: ATP dependent DNA ligase domain, PF04679: ATP dependent DNA ligase C terminal region.

Gene families : OG_01_0002002 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002002_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1304100
Cluster	P. falciparum: Cluster_30

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0000287	magnesium ion binding	IDA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003909	DNA ligase activity	None	Extended
MF	GO:0003910	DNA ligase (ATP) activity	IDA	PlasmoDB
MF	GO:0003910	DNA ligase (ATP) activity	IEA	Interproscan predictions
MF	GO:0003910	DNA ligase (ATP) activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005509	calcium ion binding	IDA	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005657	replication fork	ISS	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006266	DNA ligation	ISS	PlasmoDB
BP	GO:0006271	DNA strand elongation involved in DNA replication	None	Extended
BP	GO:0006273	lagging strand elongation	ISS	PlasmoDB
BP	GO:0006281	DNA repair	IEA	Interproscan predictions
BP	GO:0006281	DNA repair	IEA	PlasmoDB
BP	GO:0006310	DNA recombination	IEA	Interproscan predictions
BP	GO:0006310	DNA recombination	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
CC	GO:0020011	apicoplast	RCA	PlasmoDB
BP	GO:0022616	DNA strand elongation	None	Extended
MF	GO:0030145	manganese ion binding	IDA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044427	chromosomal part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051103	DNA ligation involved in DNA repair	IEA	PlasmoDB
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071897	DNA biosynthetic process	IEA	PlasmoDB
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000786	nucleosome	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
CC	GO:0032993	protein-DNA complex	IEP	Predicted GO
CC	GO:0044815	DNA packaging complex	IEP	Predicted GO
MF	GO:0046982	protein heterodimerization activity	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR012308	DNA_ligase_ATP-dep_N	177	356
IPR012310	DNA_ligase_ATP-dep_cent	536	740
IPR012309	DNA_ligase_ATP-dep_C	765	876

External Links

PlasmoDB	813777
PlasmoDB	MAL13P1.22

PF3D7_1304100 (LigI)

Expression Profile

Co-expression Networks

Functional Annotation