PF3D7_1311900 (vapA)

Aliases : vapA

Description : SSF50615: "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily", SSF47917: No description available, SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF00006: "ATP synthase alpha/beta family, nucleotide-binding domain", PF02874: "ATP synthase alpha/beta family, beta-barrel domain", PF16886: ATPsynthase alpha/beta subunit N-term extension.

Gene families : OG_01_0002038 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002038_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1311900
Cluster	P. falciparum: Cluster_30

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
CC	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	ISS	PlasmoDB
CC	GO:0000323	lytic vacuole	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005764	lysosome	None	Extended
CC	GO:0005767	secondary lysosome	None	Extended
CC	GO:0005773	vacuole	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006811	ion transport	None	Extended
BP	GO:0006812	cation transport	None	Extended
BP	GO:0006873	cellular ion homeostasis	None	Extended
BP	GO:0006885	regulation of pH	None	Extended
BP	GO:0007035	vacuolar acidification	ISS	PlasmoDB
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008324	cation transmembrane transporter activity	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009141	nucleoside triphosphate metabolic process	None	Extended
BP	GO:0009144	purine nucleoside triphosphate metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009199	ribonucleoside triphosphate metabolic process	None	Extended
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0015075	ion transmembrane transporter activity	None	Extended
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	None	Extended
MF	GO:0015078	proton transmembrane transporter activity	None	Extended
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
BP	GO:0015672	monovalent inorganic cation transport	None	Extended
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	None	Extended
BP	GO:0015991	ATP hydrolysis coupled proton transport	ISS	PlasmoDB
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEA	PlasmoDB
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
BP	GO:0017144	drug metabolic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0019725	cellular homeostasis	None	Extended
MF	GO:0019829	cation-transporting ATPase activity	None	Extended
CC	GO:0020020	food vacuole	IDA	PlasmoDB
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022853	active ion transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0022890	inorganic cation transmembrane transporter activity	None	Extended
BP	GO:0030003	cellular cation homeostasis	None	Extended
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	None	Extended
CC	GO:0030139	endocytic vesicle	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
BP	GO:0030641	regulation of cellular pH	None	Extended
CC	GO:0031410	cytoplasmic vesicle	None	Extended
CC	GO:0031982	vesicle	None	Extended
CC	GO:0032010	phagolysosome	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	None	Extended
CC	GO:0033180	proton-transporting V-type ATPase, V1 domain	IEA	PlasmoDB
BP	GO:0034220	ion transmembrane transport	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0036442	proton-exporting ATPase activity	None	Extended
BP	GO:0042592	homeostatic process	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042625	ATPase coupled ion transmembrane transporter activity	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044437	vacuolar part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	None	Extended
CC	GO:0045335	phagocytic vesicle	None	Extended
BP	GO:0045851	pH reduction	None	Extended
BP	GO:0046034	ATP metabolic process	IEA	Interproscan predictions
BP	GO:0046034	ATP metabolic process	IEA	PlasmoDB
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEA	PlasmoDB
BP	GO:0048878	chemical homeostasis	None	Extended
BP	GO:0050801	ion homeostasis	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051452	intracellular pH reduction	None	Extended
BP	GO:0051453	regulation of intracellular pH	None	Extended
BP	GO:0055067	monovalent inorganic cation homeostasis	None	Extended
BP	GO:0055080	cation homeostasis	None	Extended
BP	GO:0055082	cellular chemical homeostasis	None	Extended
BP	GO:0055085	transmembrane transport	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
CC	GO:0097708	intracellular vesicle	None	Extended
BP	GO:0098655	cation transmembrane transport	None	Extended
BP	GO:0098660	inorganic ion transmembrane transport	None	Extended
BP	GO:0098662	inorganic cation transmembrane transport	None	Extended
BP	GO:0098771	inorganic ion homeostasis	None	Extended
CC	GO:0098796	membrane protein complex	None	Extended
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	None	Extended
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1902600	proton transmembrane transport	IEA	Interproscan predictions
BP	GO:1902600	proton transmembrane transport	IEA	PlasmoDB

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Type	GO Term	Name	Evidence	Source
BP	GO:0000226	microtubule cytoskeleton organization	IEP	Predicted GO
BP	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	IEP	Predicted GO
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	IEP	Predicted GO
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0003785	actin monomer binding	IEP	Predicted GO
MF	GO:0003924	GTPase activity	IEP	Predicted GO
MF	GO:0004129	cytochrome-c oxidase activity	IEP	Predicted GO
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005686	U2 snRNP	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Predicted GO
BP	GO:0006402	mRNA catabolic process	IEP	Predicted GO
BP	GO:0006405	RNA export from nucleus	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006655	phosphatidylglycerol biosynthetic process	IEP	Predicted GO
BP	GO:0006848	pyruvate transport	IEP	Predicted GO
BP	GO:0006850	mitochondrial pyruvate transmembrane transport	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
BP	GO:0007010	cytoskeleton organization	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
MF	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	IEP	Predicted GO
MF	GO:0008521	acetyl-CoA transmembrane transporter activity	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009060	aerobic respiration	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
MF	GO:0015002	heme-copper terminal oxidase activity	IEP	Predicted GO
MF	GO:0015215	nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015216	purine nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Predicted GO
CC	GO:0015629	actin cytoskeleton	IEP	Predicted GO
BP	GO:0015980	energy derivation by oxidation of organic compounds	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	IEP	Predicted GO
MF	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	IEP	Predicted GO
MF	GO:0017169	CDP-alcohol phosphatidyltransferase activity	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0030029	actin filament-based process	IEP	Predicted GO
BP	GO:0030036	actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0030048	actin filament-based movement	IEP	Predicted GO
MF	GO:0030145	manganese ion binding	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
BP	GO:0045333	cellular respiration	IEP	Predicted GO
BP	GO:0046471	phosphatidylglycerol metabolic process	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
MF	GO:0050072	m7G(5')pppN diphosphatase activity	IEP	Predicted GO
BP	GO:0051014	actin filament severing	IEP	Predicted GO
BP	GO:0051168	nuclear export	IEP	Predicted GO
MF	GO:0051184	cofactor transmembrane transporter activity	IEP	Predicted GO
MF	GO:0051185	coenzyme transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051259	protein complex oligomerization	IEP	Predicted GO
BP	GO:0051262	protein tetramerization	IEP	Predicted GO
BP	GO:0051726	regulation of cell cycle	IEP	Predicted GO
BP	GO:0052646	alditol phosphate metabolic process	IEP	Predicted GO
BP	GO:0060327	cytoplasmic actin-based contraction involved in cell motility	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0070252	actin-mediated cell contraction	IEP	Predicted GO
MF	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
CC	GO:0089701	U2AF	IEP	Predicted GO
BP	GO:0098656	anion transmembrane transport	IEP	Predicted GO
BP	GO:1901475	pyruvate transmembrane transport	IEP	Predicted GO
MF	GO:1901682	sulfur compound transmembrane transporter activity	IEP	Predicted GO
BP	GO:1903825	organic acid transmembrane transport	IEP	Predicted GO
BP	GO:1905039	carboxylic acid transmembrane transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004100	ATPase_F1/V1/A1_a/bsu_N	14	76
IPR031686	ATP-synth_a_Xtn	92	214
IPR000194	ATPase_F1/V1/A1_a/bsu_nucl-bd	224	449

External Links

PlasmoDB	814043
PlasmoDB	PF13_0065

PF3D7_1311900 (vapA)

Expression Profile

Co-expression Networks

Functional Annotation