Aliases : LDH
Description : SSF51735: NAD(P)-binding domain superfamily, SSF56327: "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal". Pfam domain(s): PF02866: "lactate/malate dehydrogenase, alpha/beta C-terminal domain", PF00056: "lactate/malate dehydrogenase, NAD binding domain".
Gene families : OG_01_0000387 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000387_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pfa RNA-seq: PF3D7_1324900 | |
Cluster | P. falciparum: Cluster_11 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
PBANKA_1340100 | LDH | SSF51735: NAD(P)-binding domain superfamily, SSF56327:... | 0.2 | Orthofinderv1.1.8 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003824 | catalytic activity | IEA | PlasmoDB |
MF | GO:0004459 | L-lactate dehydrogenase activity | TAS | PlasmoDB |
MF | GO:0005515 | protein binding | IPI | PlasmoDB |
CC | GO:0005622 | intracellular | ISO | PlasmoDB |
BP | GO:0005975 | carbohydrate metabolic process | IEA | PlasmoDB |
BP | GO:0006096 | glycolytic process | TAS | PlasmoDB |
CC | GO:0009986 | cell surface | RCA | PlasmoDB |
MF | GO:0016491 | oxidoreductase activity | IEA | Interproscan predictions |
MF | GO:0016491 | oxidoreductase activity | IEA | PlasmoDB |
MF | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA | Interproscan predictions |
MF | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA | PlasmoDB |
BP | GO:0019752 | carboxylic acid metabolic process | IEA | PlasmoDB |
BP | GO:0055114 | oxidation-reduction process | IEA | Interproscan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | PlasmoDB |
CC | GO:1903561 | extracellular vesicle | RCA | PlasmoDB |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0000015 | phosphopyruvate hydratase complex | IEP | Predicted GO |
BP | GO:0000045 | autophagosome assembly | IEP | Predicted GO |
MF | GO:0000287 | magnesium ion binding | IEP | Predicted GO |
MF | GO:0000339 | RNA cap binding | IEP | Predicted GO |
BP | GO:0000375 | RNA splicing, via transesterification reactions | IEP | Predicted GO |
BP | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | IEP | Predicted GO |
BP | GO:0000398 | mRNA splicing, via spliceosome | IEP | Predicted GO |
BP | GO:0001678 | cellular glucose homeostasis | IEP | Predicted GO |
CC | GO:0002189 | ribose phosphate diphosphokinase complex | IEP | Predicted GO |
BP | GO:0002253 | activation of immune response | IEP | Predicted GO |
BP | GO:0002684 | positive regulation of immune system process | IEP | Predicted GO |
MF | GO:0003676 | nucleic acid binding | IEP | Predicted GO |
MF | GO:0003723 | RNA binding | IEP | Predicted GO |
MF | GO:0003725 | double-stranded RNA binding | IEP | Predicted GO |
MF | GO:0003729 | mRNA binding | IEP | Predicted GO |
MF | GO:0003735 | structural constituent of ribosome | IEP | Predicted GO |
MF | GO:0003746 | translation elongation factor activity | IEP | Predicted GO |
MF | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity | IEP | Predicted GO |
MF | GO:0004365 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | IEP | Predicted GO |
MF | GO:0004396 | hexokinase activity | IEP | Predicted GO |
MF | GO:0004618 | phosphoglycerate kinase activity | IEP | Predicted GO |
MF | GO:0004619 | phosphoglycerate mutase activity | IEP | Predicted GO |
MF | GO:0004634 | phosphopyruvate hydratase activity | IEP | Predicted GO |
MF | GO:0004731 | purine-nucleoside phosphorylase activity | IEP | Predicted GO |
MF | GO:0004735 | pyrroline-5-carboxylate reductase activity | IEP | Predicted GO |
MF | GO:0004743 | pyruvate kinase activity | IEP | Predicted GO |
MF | GO:0004749 | ribose phosphate diphosphokinase activity | IEP | Predicted GO |
MF | GO:0004812 | aminoacyl-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0004814 | arginine-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0004816 | asparagine-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0004824 | lysine-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0004828 | serine-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0005198 | structural molecule activity | IEP | Predicted GO |
MF | GO:0005536 | glucose binding | IEP | Predicted GO |
CC | GO:0005746 | mitochondrial respirasome | IEP | Predicted GO |
CC | GO:0005829 | cytosol | IEP | Predicted GO |
CC | GO:0005840 | ribosome | IEP | Predicted GO |
CC | GO:0005956 | protein kinase CK2 complex | IEP | Predicted GO |
BP | GO:0005996 | monosaccharide metabolic process | IEP | Predicted GO |
BP | GO:0006006 | glucose metabolic process | IEP | Predicted GO |
BP | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0006094 | gluconeogenesis | IEP | Predicted GO |
BP | GO:0006148 | inosine catabolic process | IEP | Predicted GO |
BP | GO:0006152 | purine nucleoside catabolic process | IEP | Predicted GO |
BP | GO:0006366 | transcription by RNA polymerase II | IEP | Predicted GO |
BP | GO:0006397 | mRNA processing | IEP | Predicted GO |
BP | GO:0006399 | tRNA metabolic process | IEP | Predicted GO |
BP | GO:0006412 | translation | IEP | Predicted GO |
BP | GO:0006414 | translational elongation | IEP | Predicted GO |
BP | GO:0006418 | tRNA aminoacylation for protein translation | IEP | Predicted GO |
BP | GO:0006420 | arginyl-tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0006421 | asparaginyl-tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0006430 | lysyl-tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0006434 | seryl-tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0006449 | regulation of translational termination | IEP | Predicted GO |
BP | GO:0006452 | translational frameshifting | IEP | Predicted GO |
BP | GO:0006518 | peptide metabolic process | IEP | Predicted GO |
BP | GO:0006520 | cellular amino acid metabolic process | IEP | Predicted GO |
BP | GO:0006528 | asparagine metabolic process | IEP | Predicted GO |
BP | GO:0006529 | asparagine biosynthetic process | IEP | Predicted GO |
BP | GO:0006560 | proline metabolic process | IEP | Predicted GO |
BP | GO:0006561 | proline biosynthetic process | IEP | Predicted GO |
MF | GO:0008097 | 5S rRNA binding | IEP | Predicted GO |
MF | GO:0008135 | translation factor activity, RNA binding | IEP | Predicted GO |
MF | GO:0008379 | thioredoxin peroxidase activity | IEP | Predicted GO |
BP | GO:0008380 | RNA splicing | IEP | Predicted GO |
BP | GO:0008652 | cellular amino acid biosynthetic process | IEP | Predicted GO |
BP | GO:0009059 | macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0009067 | aspartate family amino acid biosynthetic process | IEP | Predicted GO |
BP | GO:0009164 | nucleoside catabolic process | IEP | Predicted GO |
BP | GO:0009891 | positive regulation of biosynthetic process | IEP | Predicted GO |
BP | GO:0010557 | positive regulation of macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0010628 | positive regulation of gene expression | IEP | Predicted GO |
CC | GO:0015934 | large ribosomal subunit | IEP | Predicted GO |
CC | GO:0015935 | small ribosomal subunit | IEP | Predicted GO |
BP | GO:0015959 | diadenosine polyphosphate metabolic process | IEP | Predicted GO |
BP | GO:0015960 | diadenosine polyphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0015965 | diadenosine tetraphosphate metabolic process | IEP | Predicted GO |
BP | GO:0015966 | diadenosine tetraphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0016051 | carbohydrate biosynthetic process | IEP | Predicted GO |
BP | GO:0016070 | RNA metabolic process | IEP | Predicted GO |
BP | GO:0016071 | mRNA metabolic process | IEP | Predicted GO |
CC | GO:0016281 | eukaryotic translation initiation factor 4F complex | IEP | Predicted GO |
MF | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | IEP | Predicted GO |
MF | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor | IEP | Predicted GO |
MF | GO:0016835 | carbon-oxygen lyase activity | IEP | Predicted GO |
MF | GO:0016836 | hydro-lyase activity | IEP | Predicted GO |
MF | GO:0016874 | ligase activity | IEP | Predicted GO |
MF | GO:0016875 | ligase activity, forming carbon-oxygen bonds | IEP | Predicted GO |
MF | GO:0019200 | carbohydrate kinase activity | IEP | Predicted GO |
BP | GO:0019318 | hexose metabolic process | IEP | Predicted GO |
BP | GO:0019319 | hexose biosynthetic process | IEP | Predicted GO |
BP | GO:0019538 | protein metabolic process | IEP | Predicted GO |
MF | GO:0019843 | rRNA binding | IEP | Predicted GO |
CC | GO:0022625 | cytosolic large ribosomal subunit | IEP | Predicted GO |
CC | GO:0022627 | cytosolic small ribosomal subunit | IEP | Predicted GO |
BP | GO:0030091 | protein repair | IEP | Predicted GO |
MF | GO:0030621 | U4 snRNA binding | IEP | Predicted GO |
BP | GO:0031328 | positive regulation of cellular biosynthetic process | IEP | Predicted GO |
BP | GO:0032270 | positive regulation of cellular protein metabolic process | IEP | Predicted GO |
CC | GO:0032991 | protein-containing complex | IEP | Predicted GO |
BP | GO:0033500 | carbohydrate homeostasis | IEP | Predicted GO |
MF | GO:0033677 | DNA/RNA helicase activity | IEP | Predicted GO |
MF | GO:0033679 | 3'-5' DNA/RNA helicase activity | IEP | Predicted GO |
BP | GO:0034250 | positive regulation of cellular amide metabolic process | IEP | Predicted GO |
MF | GO:0034511 | U3 snoRNA binding | IEP | Predicted GO |
BP | GO:0034645 | cellular macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0034656 | nucleobase-containing small molecule catabolic process | IEP | Predicted GO |
BP | GO:0035915 | pore formation in membrane of other organism | IEP | Predicted GO |
MF | GO:0036524 | protein deglycase activity | IEP | Predicted GO |
BP | GO:0036525 | protein deglycation | IEP | Predicted GO |
BP | GO:0042255 | ribosome assembly | IEP | Predicted GO |
BP | GO:0042256 | mature ribosome assembly | IEP | Predicted GO |
BP | GO:0042262 | DNA protection | IEP | Predicted GO |
BP | GO:0042454 | ribonucleoside catabolic process | IEP | Predicted GO |
BP | GO:0042593 | glucose homeostasis | IEP | Predicted GO |
MF | GO:0043021 | ribonucleoprotein complex binding | IEP | Predicted GO |
MF | GO:0043022 | ribosome binding | IEP | Predicted GO |
MF | GO:0043023 | ribosomal large subunit binding | IEP | Predicted GO |
BP | GO:0043038 | amino acid activation | IEP | Predicted GO |
BP | GO:0043039 | tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0043043 | peptide biosynthetic process | IEP | Predicted GO |
BP | GO:0043170 | macromolecule metabolic process | IEP | Predicted GO |
CC | GO:0043228 | non-membrane-bounded organelle | IEP | Predicted GO |
CC | GO:0043229 | intracellular organelle | IEP | Predicted GO |
CC | GO:0043232 | intracellular non-membrane-bounded organelle | IEP | Predicted GO |
BP | GO:0043243 | positive regulation of protein complex disassembly | IEP | Predicted GO |
BP | GO:0043244 | regulation of protein complex disassembly | IEP | Predicted GO |
BP | GO:0043603 | cellular amide metabolic process | IEP | Predicted GO |
BP | GO:0043604 | amide biosynthetic process | IEP | Predicted GO |
MF | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity | IEP | Predicted GO |
CC | GO:0044161 | host cell cytoplasmic vesicle | IEP | Predicted GO |
BP | GO:0044260 | cellular macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0044267 | cellular protein metabolic process | IEP | Predicted GO |
CC | GO:0044391 | ribosomal subunit | IEP | Predicted GO |
CC | GO:0044422 | organelle part | IEP | Predicted GO |
CC | GO:0044424 | intracellular part | IEP | Predicted GO |
CC | GO:0044444 | cytoplasmic part | IEP | Predicted GO |
CC | GO:0044445 | cytosolic part | IEP | Predicted GO |
CC | GO:0044446 | intracellular organelle part | IEP | Predicted GO |
BP | GO:0044657 | pore formation in membrane of other organism during symbiotic interaction | IEP | Predicted GO |
BP | GO:0044658 | pore formation in membrane of host by symbiont | IEP | Predicted GO |
MF | GO:0044877 | protein-containing complex binding | IEP | Predicted GO |
BP | GO:0045727 | positive regulation of translation | IEP | Predicted GO |
BP | GO:0045901 | positive regulation of translational elongation | IEP | Predicted GO |
BP | GO:0045905 | positive regulation of translational termination | IEP | Predicted GO |
BP | GO:0046102 | inosine metabolic process | IEP | Predicted GO |
BP | GO:0046130 | purine ribonucleoside catabolic process | IEP | Predicted GO |
BP | GO:0046364 | monosaccharide biosynthetic process | IEP | Predicted GO |
BP | GO:0046391 | 5-phosphoribose 1-diphosphate metabolic process | IEP | Predicted GO |
MF | GO:0048029 | monosaccharide binding | IEP | Predicted GO |
BP | GO:0048518 | positive regulation of biological process | IEP | Predicted GO |
BP | GO:0048584 | positive regulation of response to stimulus | IEP | Predicted GO |
BP | GO:0050778 | positive regulation of immune response | IEP | Predicted GO |
BP | GO:0051247 | positive regulation of protein metabolic process | IEP | Predicted GO |
BP | GO:0051260 | protein homooligomerization | IEP | Predicted GO |
BP | GO:0051262 | protein tetramerization | IEP | Predicted GO |
BP | GO:0051289 | protein homotetramerization | IEP | Predicted GO |
BP | GO:0051673 | membrane disruption in other organism | IEP | Predicted GO |
BP | GO:0052025 | modification by symbiont of host cell membrane | IEP | Predicted GO |
BP | GO:0052043 | modification by symbiont of host cellular component | IEP | Predicted GO |
BP | GO:0052111 | modification by symbiont of host structure | IEP | Predicted GO |
BP | GO:0052185 | modification of structure of other organism involved in symbiotic interaction | IEP | Predicted GO |
BP | GO:0052188 | modification of cellular component in other organism involved in symbiotic interaction | IEP | Predicted GO |
BP | GO:0052332 | modification by organism of membrane in other organism involved in symbiotic interaction | IEP | Predicted GO |
CC | GO:0061695 | transferase complex, transferring phosphorus-containing groups | IEP | Predicted GO |
CC | GO:0070469 | respirasome | IEP | Predicted GO |
BP | GO:0070925 | organelle assembly | IEP | Predicted GO |
BP | GO:0090304 | nucleic acid metabolic process | IEP | Predicted GO |
MF | GO:0097159 | organic cyclic compound binding | IEP | Predicted GO |
MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
MF | GO:0140101 | catalytic activity, acting on a tRNA | IEP | Predicted GO |
MF | GO:1901363 | heterocyclic compound binding | IEP | Predicted GO |
BP | GO:1901605 | alpha-amino acid metabolic process | IEP | Predicted GO |
BP | GO:1901607 | alpha-amino acid biosynthetic process | IEP | Predicted GO |
BP | GO:1901658 | glycosyl compound catabolic process | IEP | Predicted GO |
BP | GO:1905037 | autophagosome organization | IEP | Predicted GO |
CC | GO:1990904 | ribonucleoprotein complex | IEP | Predicted GO |