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  5. PF3D7_1329300

PF3D7_1329300 (CAF2)


Aliases : CAF2

Description : SSF50978: WD40-repeat-containing domain superfamily. Pfam domain(s): PF00400: "WD domain, G-beta repeat", PF12265: Histone-binding protein RBBP4 or subunit C of CAF1 complex.


Gene families : OG_01_0001905 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001905_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_1329300
Cluster P. falciparum: Cluster_10

Target Alias Description ECC score Gene Family Method Actions
PBANKA_1344300 CAF2 SSF50978: WD40-repeat-containing domain superfamily.... 0.07 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IPI PlasmoDB
MF GO:0005515 protein binding IEA Interproscan predictions
MF GO:0005515 protein binding IEA PlasmoDB
CC GO:0005634 nucleus IDA PlasmoDB
BP GO:0031497 chromatin assembly ISS PlasmoDB
MF GO:0042393 histone binding ISS PlasmoDB
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Type GO Term Name Evidence Source
CC GO:0000311 plastid large ribosomal subunit IEP Predicted GO
CC GO:0000315 organellar large ribosomal subunit IEP Predicted GO
CC GO:0000932 P-body IEP Predicted GO
BP GO:0001505 regulation of neurotransmitter levels IEP Predicted GO
BP GO:0002376 immune system process IEP Predicted GO
BP GO:0002377 immunoglobulin production IEP Predicted GO
BP GO:0002440 production of molecular mediator of immune response IEP Predicted GO
BP GO:0002682 regulation of immune system process IEP Predicted GO
MF GO:0003689 DNA clamp loader activity IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003729 mRNA binding IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0003896 DNA primase activity IEP Predicted GO
MF GO:0004140 dephospho-CoA kinase activity IEP Predicted GO
MF GO:0004146 dihydrofolate reductase activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0004353 glutamate dehydrogenase [NAD(P)+] activity IEP Predicted GO
MF GO:0004354 glutamate dehydrogenase (NADP+) activity IEP Predicted GO
MF GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity IEP Predicted GO
MF GO:0004372 glycine hydroxymethyltransferase activity IEP Predicted GO
MF GO:0004799 thymidylate synthase activity IEP Predicted GO
MF GO:0005385 zinc ion transmembrane transporter activity IEP Predicted GO
CC GO:0005672 transcription factor TFIIA complex IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006066 alcohol metabolic process IEP Predicted GO
BP GO:0006108 malate metabolic process IEP Predicted GO
BP GO:0006116 NADH oxidation IEP Predicted GO
BP GO:0006127 glycerophosphate shuttle IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006231 dTMP biosynthetic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006260 DNA replication IEP Predicted GO
BP GO:0006269 DNA replication, synthesis of RNA primer IEP Predicted GO
BP GO:0006270 DNA replication initiation IEP Predicted GO
BP GO:0006378 mRNA polyadenylation IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006537 glutamate biosynthetic process IEP Predicted GO
BP GO:0006544 glycine metabolic process IEP Predicted GO
BP GO:0006545 glycine biosynthetic process IEP Predicted GO
BP GO:0006563 L-serine metabolic process IEP Predicted GO
BP GO:0006575 cellular modified amino acid metabolic process IEP Predicted GO
BP GO:0006720 isoprenoid metabolic process IEP Predicted GO
BP GO:0006721 terpenoid metabolic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006730 one-carbon metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006734 NADH metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006760 folic acid-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006829 zinc ion transport IEP Predicted GO
BP GO:0006891 intra-Golgi vesicle-mediated transport IEP Predicted GO
MF GO:0008094 DNA-dependent ATPase activity IEP Predicted GO
MF GO:0008121 ubiquinol-cytochrome-c reductase activity IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
BP GO:0008299 isoprenoid biosynthetic process IEP Predicted GO
BP GO:0008652 cellular amino acid biosynthetic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009069 serine family amino acid metabolic process IEP Predicted GO
BP GO:0009070 serine family amino acid biosynthetic process IEP Predicted GO
BP GO:0009084 glutamine family amino acid biosynthetic process IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009129 pyrimidine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009157 deoxyribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009162 deoxyribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009219 pyrimidine deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009265 2'-deoxyribonucleotide biosynthetic process IEP Predicted GO
CC GO:0009331 glycerol-3-phosphate dehydrogenase complex IEP Predicted GO
CC GO:0009376 HslUV protease complex IEP Predicted GO
BP GO:0009394 2'-deoxyribonucleotide metabolic process IEP Predicted GO
CC GO:0009536 plastid IEP Predicted GO
BP GO:0010035 response to inorganic substance IEP Predicted GO
BP GO:0010038 response to metal ion IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
BP GO:0016093 polyprenol metabolic process IEP Predicted GO
BP GO:0016094 polyprenol biosynthetic process IEP Predicted GO
BP GO:0016114 terpenoid biosynthetic process IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016615 malate dehydrogenase activity IEP Predicted GO
MF GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IEP Predicted GO
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors IEP Predicted GO
MF GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor IEP Predicted GO
MF GO:0016742 hydroxymethyl-, formyl- and related transferase activity IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0019264 glycine biosynthetic process from serine IEP Predicted GO
BP GO:0019348 dolichol metabolic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019408 dolichol biosynthetic process IEP Predicted GO
BP GO:0019674 NAD metabolic process IEP Predicted GO
BP GO:0019692 deoxyribose phosphate metabolic process IEP Predicted GO
CC GO:0020011 apicoplast IEP Predicted GO
MF GO:0030060 L-malate dehydrogenase activity IEP Predicted GO
CC GO:0030121 AP-1 adaptor complex IEP Predicted GO
CC GO:0030127 COPII vesicle coat IEP Predicted GO
BP GO:0031124 mRNA 3'-end processing IEP Predicted GO
CC GO:0031597 cytosolic proteasome complex IEP Predicted GO
BP GO:0032879 regulation of localization IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033043 regulation of organelle organization IEP Predicted GO
BP GO:0033044 regulation of chromosome organization IEP Predicted GO
MF GO:0033170 protein-DNA loading ATPase activity IEP Predicted GO
BP GO:0034308 primary alcohol metabolic process IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0035999 tetrahydrofolate interconversion IEP Predicted GO
MF GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity IEP Predicted GO
BP GO:0042133 neurotransmitter metabolic process IEP Predicted GO
BP GO:0042136 neurotransmitter biosynthetic process IEP Predicted GO
CC GO:0042555 MCM complex IEP Predicted GO
BP GO:0042558 pteridine-containing compound metabolic process IEP Predicted GO
MF GO:0042623 ATPase activity, coupled IEP Predicted GO
CC GO:0043186 P granule IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0043648 dicarboxylic acid metabolic process IEP Predicted GO
BP GO:0043650 dicarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044435 plastid part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
BP GO:0046073 dTMP metabolic process IEP Predicted GO
BP GO:0046385 deoxyribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046416 D-amino acid metabolic process IEP Predicted GO
MF GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046653 tetrahydrofolate metabolic process IEP Predicted GO
BP GO:0046654 tetrahydrofolate biosynthetic process IEP Predicted GO
BP GO:0048193 Golgi vesicle transport IEP Predicted GO
BP GO:0048519 negative regulation of biological process IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
BP GO:0050776 regulation of immune response IEP Predicted GO
BP GO:0051049 regulation of transport IEP Predicted GO
BP GO:0051095 regulation of helicase activity IEP Predicted GO
BP GO:0051097 negative regulation of helicase activity IEP Predicted GO
BP GO:0051128 regulation of cellular component organization IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
BP GO:0051346 negative regulation of hydrolase activity IEP Predicted GO
MF GO:0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0060627 regulation of vesicle-mediated transport IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
BP GO:0070178 D-serine metabolic process IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
MF GO:0072509 divalent inorganic cation transmembrane transporter activity IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1901605 alpha-amino acid metabolic process IEP Predicted GO
BP GO:1901607 alpha-amino acid biosynthetic process IEP Predicted GO
BP GO:1901615 organic hydroxy compound metabolic process IEP Predicted GO
BP GO:1905462 regulation of DNA duplex unwinding IEP Predicted GO
BP GO:1905463 negative regulation of DNA duplex unwinding IEP Predicted GO
BP GO:1905774 regulation of DNA helicase activity IEP Predicted GO
BP GO:1905775 negative regulation of DNA helicase activity IEP Predicted GO
CC GO:1990229 iron-sulfur cluster assembly complex IEP Predicted GO
BP GO:2001251 negative regulation of chromosome organization IEP Predicted GO
InterPro domains Description Start Stop
IPR022052 Histone-bd_RBBP4_N 41 109
IPR001680 WD40_repeat 285 339
IPR001680 WD40_repeat 476 507
IPR001680 WD40_repeat 536 573
PlasmoDB 814119
PlasmoDB PF13_0149