PF3D7_1331300 (SEC11)

Aliases : SEC11

Description : SSF51306: LexA/Signal peptidase-like superfamily. Pfam domain(s): PF00717: Peptidase S24-like.

Gene families : OG_01_0001911 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001911_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1331300
Cluster	P. falciparum: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1346200	SEC11	SSF51306: LexA/Signal peptidase-like superfamily. Pfam...	0.08	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005783	endoplasmic reticulum	IDA	PlasmoDB
CC	GO:0005787	signal peptidase complex	IDA	PlasmoDB
BP	GO:0006465	signal peptide processing	ISS	PlasmoDB
BP	GO:0006465	signal peptide processing	IEA	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006518	peptide metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	ISS	PlasmoDB
MF	GO:0008233	peptidase activity	IEA	PlasmoDB
MF	GO:0008236	serine-type peptidase activity	IEA	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
CC	GO:0016020	membrane	IEA	PlasmoDB
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
BP	GO:0016485	protein processing	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0017171	serine hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044432	endoplasmic reticulum part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051604	protein maturation	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0098796	membrane protein complex	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1905368	peptidase complex	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	IEP	Predicted GO
MF	GO:0000225	N-acetylglucosaminylphosphatidylinositol deacetylase activity	IEP	Predicted GO
MF	GO:0000234	phosphoethanolamine N-methyltransferase activity	IEP	Predicted GO
CC	GO:0000315	organellar large ribosomal subunit	IEP	Predicted GO
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
CC	GO:0000502	proteasome complex	IEP	Predicted GO
CC	GO:0000791	euchromatin	IEP	Predicted GO
MF	GO:0003689	DNA clamp loader activity	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0003909	DNA ligase activity	IEP	Predicted GO
MF	GO:0003911	DNA ligase (NAD+) activity	IEP	Predicted GO
MF	GO:0003998	acylphosphatase activity	IEP	Predicted GO
MF	GO:0004013	adenosylhomocysteinase activity	IEP	Predicted GO
MF	GO:0004129	cytochrome-c oxidase activity	IEP	Predicted GO
MF	GO:0004170	dUTP diphosphatase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004368	glycerol-3-phosphate dehydrogenase (quinone) activity	IEP	Predicted GO
MF	GO:0004372	glycine hydroxymethyltransferase activity	IEP	Predicted GO
MF	GO:0004392	heme oxygenase (decyclizing) activity	IEP	Predicted GO
MF	GO:0004602	glutathione peroxidase activity	IEP	Predicted GO
MF	GO:0004774	succinate-CoA ligase activity	IEP	Predicted GO
MF	GO:0004776	succinate-CoA ligase (GDP-forming) activity	IEP	Predicted GO
MF	GO:0004784	superoxide dismutase activity	IEP	Predicted GO
MF	GO:0004791	thioredoxin-disulfide reductase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005342	organic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005375	copper ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005483	soluble NSF attachment protein activity	IEP	Predicted GO
CC	GO:0005663	DNA replication factor C complex	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005740	mitochondrial envelope	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
CC	GO:0005750	mitochondrial respiratory chain complex III	IEP	Predicted GO
CC	GO:0005762	mitochondrial large ribosomal subunit	IEP	Predicted GO
CC	GO:0005813	centrosome	IEP	Predicted GO
CC	GO:0005815	microtubule organizing center	IEP	Predicted GO
CC	GO:0005838	proteasome regulatory particle	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
BP	GO:0006066	alcohol metabolic process	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006099	tricarboxylic acid cycle	IEP	Predicted GO
BP	GO:0006101	citrate metabolic process	IEP	Predicted GO
BP	GO:0006104	succinyl-CoA metabolic process	IEP	Predicted GO
BP	GO:0006108	malate metabolic process	IEP	Predicted GO
BP	GO:0006116	NADH oxidation	IEP	Predicted GO
BP	GO:0006119	oxidative phosphorylation	IEP	Predicted GO
BP	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	IEP	Predicted GO
BP	GO:0006127	glycerophosphate shuttle	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006183	GTP biosynthetic process	IEP	Predicted GO
BP	GO:0006228	UTP biosynthetic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006271	DNA strand elongation involved in DNA replication	IEP	Predicted GO
BP	GO:0006272	leading strand elongation	IEP	Predicted GO
BP	GO:0006458	'de novo' protein folding	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006545	glycine biosynthetic process	IEP	Predicted GO
BP	GO:0006563	L-serine metabolic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006734	NADH metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006754	ATP biosynthetic process	IEP	Predicted GO
BP	GO:0006784	heme a biosynthetic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006825	copper ion transport	IEP	Predicted GO
BP	GO:0006835	dicarboxylic acid transport	IEP	Predicted GO
BP	GO:0006979	response to oxidative stress	IEP	Predicted GO
MF	GO:0008121	ubiquinol-cytochrome-c reductase activity	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008509	anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
BP	GO:0008610	lipid biosynthetic process	IEP	Predicted GO
MF	GO:0008897	holo-[acyl-carrier-protein] synthase activity	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Predicted GO
MF	GO:0015002	heme-copper terminal oxidase activity	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015140	malate transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015367	oxoglutarate:malate antiporter activity	IEP	Predicted GO
MF	GO:0015556	C4-dicarboxylate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015672	monovalent inorganic cation transport	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015740	C4-dicarboxylate transport	IEP	Predicted GO
BP	GO:0015742	alpha-ketoglutarate transport	IEP	Predicted GO
BP	GO:0015743	malate transport	IEP	Predicted GO
BP	GO:0015849	organic acid transport	IEP	Predicted GO
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Predicted GO
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
BP	GO:0016093	polyprenol metabolic process	IEP	Predicted GO
BP	GO:0016094	polyprenol biosynthetic process	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Predicted GO
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	IEP	Predicted GO
MF	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	IEP	Predicted GO
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Predicted GO
MF	GO:0016802	trialkylsulfonium hydrolase activity	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	IEP	Predicted GO
BP	GO:0016999	antibiotic metabolic process	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
CC	GO:0019005	SCF ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0019264	glycine biosynthetic process from serine	IEP	Predicted GO
BP	GO:0019348	dolichol metabolic process	IEP	Predicted GO
BP	GO:0019408	dolichol biosynthetic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019674	NAD metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
BP	GO:0022616	DNA strand elongation	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0022900	electron transport chain	IEP	Predicted GO
BP	GO:0022904	respiratory electron transport chain	IEP	Predicted GO
CC	GO:0030134	COPII-coated ER to Golgi transport vesicle	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
CC	GO:0031090	organelle membrane	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
MF	GO:0032552	deoxyribonucleotide binding	IEP	Predicted GO
BP	GO:0032780	negative regulation of ATPase activity	IEP	Predicted GO
MF	GO:0033170	protein-DNA loading ATPase activity	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
BP	GO:0034308	primary alcohol metabolic process	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0035434	copper ion transmembrane transport	IEP	Predicted GO
BP	GO:0035999	tetrahydrofolate interconversion	IEP	Predicted GO
BP	GO:0042136	neurotransmitter biosynthetic process	IEP	Predicted GO
CC	GO:0042709	succinate-CoA ligase complex	IEP	Predicted GO
BP	GO:0043248	proteasome assembly	IEP	Predicted GO
BP	GO:0043462	regulation of ATPase activity	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Predicted GO
BP	GO:0045116	protein neddylation	IEP	Predicted GO
CC	GO:0045244	succinate-CoA ligase complex (GDP-forming)	IEP	Predicted GO
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Predicted GO
CC	GO:0045275	respiratory chain complex III	IEP	Predicted GO
BP	GO:0046034	ATP metabolic process	IEP	Predicted GO
BP	GO:0046039	GTP metabolic process	IEP	Predicted GO
BP	GO:0046051	UTP metabolic process	IEP	Predicted GO
BP	GO:0046160	heme a metabolic process	IEP	Predicted GO
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046416	D-amino acid metabolic process	IEP	Predicted GO
BP	GO:0046474	glycerophospholipid biosynthetic process	IEP	Predicted GO
MF	GO:0046915	transition metal ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0046942	carboxylic acid transport	IEP	Predicted GO
MF	GO:0046943	carboxylic acid transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051382	kinetochore assembly	IEP	Predicted GO
BP	GO:0051383	kinetochore organization	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
CC	GO:0070069	cytochrome complex	IEP	Predicted GO
BP	GO:0070178	D-serine metabolic process	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0072350	tricarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
BP	GO:0098655	cation transmembrane transport	IEP	Predicted GO
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Predicted GO
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Predicted GO
CC	GO:0098798	mitochondrial protein complex	IEP	Predicted GO
CC	GO:0098800	inner mitochondrial membrane protein complex	IEP	Predicted GO
CC	GO:0098803	respiratory chain complex	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1901615	organic hydroxy compound metabolic process	IEP	Predicted GO
BP	GO:1902600	proton transmembrane transport	IEP	Predicted GO
CC	GO:1905369	endopeptidase complex	IEP	Predicted GO
CC	GO:1990204	oxidoreductase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR015927	Peptidase_S24_S26A/B/C	59	108

External Links

PlasmoDB	813720
PlasmoDB	MAL13P1.167

PF3D7_1331300 (SEC11)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation