PF3D7_1333200 (UBA1)

Aliases : UBA1

Description : SSF69572: Ubiquitin-activating enzyme. Pfam domain(s): PF10585: Ubiquitin-activating enzyme active site, PF00899: ThiF family.

Gene families : OG_01_0004255 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0004255_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1333200
Cluster	P. falciparum: Cluster_41

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1347900	UBA1	SSF69572: Ubiquitin-activating enzyme. Pfam domain(s):...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004842	ubiquitin-protein transferase activity	IDA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006464	cellular protein modification process	IEA	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEA	Interproscan predictions
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEA	PlasmoDB
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010033	response to organic substance	None	Extended
BP	GO:0010243	response to organonitrogen compound	None	Extended
BP	GO:0010498	proteasomal protein catabolic process	None	Extended
BP	GO:0010564	regulation of cell cycle process	IDA	PlasmoDB
MF	GO:0016462	pyrophosphatase activity	None	Extended
BP	GO:0016567	protein ubiquitination	IDA	PlasmoDB
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	None	Extended
MF	GO:0016887	ATPase activity	IDA	PlasmoDB
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019787	ubiquitin-like protein transferase activity	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
BP	GO:0030163	protein catabolic process	None	Extended
BP	GO:0030433	ubiquitin-dependent ERAD pathway	EXP	PlasmoDB
BP	GO:0032446	protein modification by small protein conjugation	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034976	response to endoplasmic reticulum stress	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0036503	ERAD pathway	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0051726	regulation of cell cycle	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0070647	protein modification by small protein conjugation or removal	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901565	organonitrogen compound catabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
BP	GO:1901698	response to nitrogen compound	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
CC	GO:0000922	spindle pole	IEP	Predicted GO
MF	GO:0003690	double-stranded DNA binding	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006261	DNA-dependent DNA replication	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006721	terpenoid metabolic process	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
BP	GO:0006891	intra-Golgi vesicle-mediated transport	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
CC	GO:0008622	epsilon DNA polymerase complex	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
BP	GO:0016108	tetraterpenoid metabolic process	IEP	Predicted GO
BP	GO:0016109	tetraterpenoid biosynthetic process	IEP	Predicted GO
BP	GO:0016114	terpenoid biosynthetic process	IEP	Predicted GO
BP	GO:0016116	carotenoid metabolic process	IEP	Predicted GO
BP	GO:0016117	carotenoid biosynthetic process	IEP	Predicted GO
MF	GO:0016929	SUMO-specific protease activity	IEP	Predicted GO
CC	GO:0017119	Golgi transport complex	IEP	Predicted GO
MF	GO:0017134	fibroblast growth factor binding	IEP	Predicted GO
MF	GO:0019838	growth factor binding	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
MF	GO:0030145	manganese ion binding	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
CC	GO:0042575	DNA polymerase complex	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
MF	GO:0043015	gamma-tubulin binding	IEP	Predicted GO
CC	GO:0043190	ATP-binding cassette (ABC) transporter complex	IEP	Predicted GO
MF	GO:0043295	glutathione binding	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
CC	GO:0044431	Golgi apparatus part	IEP	Predicted GO
MF	GO:0046905	phytoene synthase activity	IEP	Predicted GO
BP	GO:0048193	Golgi vesicle transport	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
MF	GO:0072341	modified amino acid binding	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
CC	GO:0098533	ATPase dependent transmembrane transport complex	IEP	Predicted GO
CC	GO:0099023	tethering complex	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
MF	GO:1900750	oligopeptide binding	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
CC	GO:1990229	iron-sulfur cluster assembly complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR019572	UBA_E1_Cys	963	1305
IPR000594	ThiF_NAD_FAD-bd	169	315
IPR000594	ThiF_NAD_FAD-bd	795	1360

External Links

PlasmoDB	814152
PlasmoDB	PF13_0182

PF3D7_1333200 (UBA1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation