PF3D7_1338100 (RPN3)

Aliases : RPN3

Description : SSF46785: Winged helix DNA-binding domain superfamily. Pfam domain(s): PF08375: Proteasome regulatory subunit C-terminal, PF01399: PCI domain.

Gene families : OG_01_0001933 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001933_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1338100
Cluster	P. falciparum: Cluster_31

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1351800	RPN3	No superfamily available. Pfam domain(s): PF08375:...	0.05	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
CC	GO:0000502	proteasome complex	IEA	Interproscan predictions
CC	GO:0000502	proteasome complex	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	ISS	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005838	proteasome regulatory particle	ISS	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	ISS	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009894	regulation of catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
MF	GO:0030234	enzyme regulator activity	IEA	Interproscan predictions
MF	GO:0030234	enzyme regulator activity	IEA	PlasmoDB
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0042176	regulation of protein catabolic process	IEA	Interproscan predictions
BP	GO:0042176	regulation of protein catabolic process	IEA	PlasmoDB
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051246	regulation of protein metabolic process	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1905368	peptidase complex	None	Extended
CC	GO:1905369	endopeptidase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	IEP	Predicted GO
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0000234	phosphoethanolamine N-methyltransferase activity	IEP	Predicted GO
CC	GO:0000791	euchromatin	IEP	Predicted GO
BP	GO:0002376	immune system process	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002682	regulation of immune system process	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0004013	adenosylhomocysteinase activity	IEP	Predicted GO
MF	GO:0004170	dUTP diphosphatase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004368	glycerol-3-phosphate dehydrogenase (quinone) activity	IEP	Predicted GO
MF	GO:0004372	glycine hydroxymethyltransferase activity	IEP	Predicted GO
MF	GO:0004392	heme oxygenase (decyclizing) activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004784	superoxide dismutase activity	IEP	Predicted GO
MF	GO:0004791	thioredoxin-disulfide reductase activity	IEP	Predicted GO
MF	GO:0004825	methionine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004842	ubiquitin-protein transferase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005342	organic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005375	copper ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005388	calcium-transporting ATPase activity	IEP	Predicted GO
MF	GO:0005483	soluble NSF attachment protein activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005654	nucleoplasm	IEP	Predicted GO
CC	GO:0005740	mitochondrial envelope	IEP	Predicted GO
CC	GO:0005787	signal peptidase complex	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
BP	GO:0006116	NADH oxidation	IEP	Predicted GO
BP	GO:0006127	glycerophosphate shuttle	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006431	methionyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006458	'de novo' protein folding	IEP	Predicted GO
BP	GO:0006465	signal peptide processing	IEP	Predicted GO
BP	GO:0006545	glycine biosynthetic process	IEP	Predicted GO
BP	GO:0006563	L-serine metabolic process	IEP	Predicted GO
BP	GO:0006734	NADH metabolic process	IEP	Predicted GO
BP	GO:0006787	porphyrin-containing compound catabolic process	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006816	calcium ion transport	IEP	Predicted GO
BP	GO:0006825	copper ion transport	IEP	Predicted GO
BP	GO:0006848	pyruvate transport	IEP	Predicted GO
BP	GO:0006850	mitochondrial pyruvate transmembrane transport	IEP	Predicted GO
BP	GO:0007029	endoplasmic reticulum organization	IEP	Predicted GO
MF	GO:0008028	monocarboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008509	anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0009070	serine family amino acid biosynthetic process	IEP	Predicted GO
CC	GO:0009331	glycerol-3-phosphate dehydrogenase complex	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015085	calcium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015718	monocarboxylic acid transport	IEP	Predicted GO
BP	GO:0015849	organic acid transport	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
CC	GO:0016324	apical plasma membrane	IEP	Predicted GO
BP	GO:0016485	protein processing	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Predicted GO
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Predicted GO
MF	GO:0016801	hydrolase activity, acting on ether bonds	IEP	Predicted GO
MF	GO:0016802	trialkylsulfonium hydrolase activity	IEP	Predicted GO
MF	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	IEP	Predicted GO
CC	GO:0019005	SCF ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0019264	glycine biosynthetic process from serine	IEP	Predicted GO
BP	GO:0019674	NAD metabolic process	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0030001	metal ion transport	IEP	Predicted GO
MF	GO:0030337	DNA polymerase processivity factor activity	IEP	Predicted GO
BP	GO:0032780	negative regulation of ATPase activity	IEP	Predicted GO
BP	GO:0033015	tetrapyrrole catabolic process	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
BP	GO:0034308	primary alcohol metabolic process	IEP	Predicted GO
BP	GO:0035434	copper ion transmembrane transport	IEP	Predicted GO
BP	GO:0035999	tetrahydrofolate interconversion	IEP	Predicted GO
BP	GO:0042136	neurotransmitter biosynthetic process	IEP	Predicted GO
BP	GO:0042167	heme catabolic process	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043462	regulation of ATPase activity	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
BP	GO:0045116	protein neddylation	IEP	Predicted GO
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Predicted GO
BP	GO:0046149	pigment catabolic process	IEP	Predicted GO
BP	GO:0046416	D-amino acid metabolic process	IEP	Predicted GO
BP	GO:0046653	tetrahydrofolate metabolic process	IEP	Predicted GO
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0046915	transition metal ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0046942	carboxylic acid transport	IEP	Predicted GO
MF	GO:0046943	carboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0050776	regulation of immune response	IEP	Predicted GO
MF	GO:0050833	pyruvate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051187	cofactor catabolic process	IEP	Predicted GO
BP	GO:0051382	kinetochore assembly	IEP	Predicted GO
BP	GO:0051383	kinetochore organization	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
BP	GO:0070178	D-serine metabolic process	IEP	Predicted GO
MF	GO:0070628	proteasome binding	IEP	Predicted GO
CC	GO:0070971	endoplasmic reticulum exit site	IEP	Predicted GO
BP	GO:0071344	diphosphate metabolic process	IEP	Predicted GO
CC	GO:0071782	endoplasmic reticulum tubular network	IEP	Predicted GO
BP	GO:0071786	endoplasmic reticulum tubular network organization	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
CC	GO:0098590	plasma membrane region	IEP	Predicted GO
BP	GO:0098655	cation transmembrane transport	IEP	Predicted GO
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Predicted GO
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Predicted GO
CC	GO:0098827	endoplasmic reticulum subcompartment	IEP	Predicted GO
BP	GO:1901475	pyruvate transmembrane transport	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013586	26S_Psome_reg_C	434	498
IPR000717	PCI_dom	328	430

External Links

PlasmoDB	813745
PlasmoDB	MAL13P1.190

PF3D7_1338100 (RPN3)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation