PF3D7_1342800 (PEPCK)

Aliases : PEPCK

Description : SSF68923: "Phosphoenolpyruvate carboxykinase, N-terminal", SSF53795: No description available. Pfam domain(s): PF01293: Phosphoenolpyruvate carboxykinase.

Gene families : OG_01_0000393 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000393_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1342800
Cluster	P. falciparum: Cluster_4

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1355900	PEPCK	SSF68923: Phosphoenolpyruvate carboxykinase, N-terminal,...	0.12	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	None	Extended
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEA	PlasmoDB
MF	GO:0004612	phosphoenolpyruvate carboxykinase (ATP) activity	ISS	PlasmoDB
MF	GO:0004612	phosphoenolpyruvate carboxykinase (ATP) activity	IEA	Interproscan predictions
MF	GO:0004612	phosphoenolpyruvate carboxykinase (ATP) activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	ISO	PlasmoDB
BP	GO:0005975	carbohydrate metabolic process	None	Extended
BP	GO:0005996	monosaccharide metabolic process	None	Extended
BP	GO:0006006	glucose metabolic process	None	Extended
BP	GO:0006094	gluconeogenesis	ISS	PlasmoDB
BP	GO:0006094	gluconeogenesis	IEA	Interproscan predictions
BP	GO:0006094	gluconeogenesis	IEA	PlasmoDB
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0016051	carbohydrate biosynthetic process	None	Extended
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016830	carbon-carbon lyase activity	None	Extended
MF	GO:0016831	carboxy-lyase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017076	purine nucleotide binding	IEA	PlasmoDB
BP	GO:0019318	hexose metabolic process	None	Extended
BP	GO:0019319	hexose biosynthetic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046364	monosaccharide biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000150	recombinase activity	IEP	Predicted GO
BP	GO:0000717	nucleotide-excision repair, DNA duplex unwinding	IEP	Predicted GO
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Predicted GO
BP	GO:0000725	recombinational repair	IEP	Predicted GO
BP	GO:0001817	regulation of cytokine production	IEP	Predicted GO
BP	GO:0001818	negative regulation of cytokine production	IEP	Predicted GO
MF	GO:0003697	single-stranded DNA binding	IEP	Predicted GO
MF	GO:0004324	ferredoxin-NADP+ reductase activity	IEP	Predicted GO
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Predicted GO
MF	GO:0004751	ribose-5-phosphate isomerase activity	IEP	Predicted GO
CC	GO:0005892	acetylcholine-gated channel complex	IEP	Predicted GO
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006284	base-excision repair	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Predicted GO
BP	GO:0008614	pyridoxine metabolic process	IEP	Predicted GO
BP	GO:0008615	pyridoxine biosynthetic process	IEP	Predicted GO
MF	GO:0008937	ferredoxin-NAD(P) reductase activity	IEP	Predicted GO
BP	GO:0009052	pentose-phosphate shunt, non-oxidative branch	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
CC	GO:0009331	glycerol-3-phosphate dehydrogenase complex	IEP	Predicted GO
MF	GO:0016730	oxidoreductase activity, acting on iron-sulfur proteins as donors	IEP	Predicted GO
MF	GO:0016731	oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Predicted GO
BP	GO:0031297	replication fork processing	IEP	Predicted GO
BP	GO:0032675	regulation of interleukin-6 production	IEP	Predicted GO
BP	GO:0032715	negative regulation of interleukin-6 production	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
CC	GO:0034702	ion channel complex	IEP	Predicted GO
BP	GO:0042816	vitamin B6 metabolic process	IEP	Predicted GO
BP	GO:0042819	vitamin B6 biosynthetic process	IEP	Predicted GO
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Predicted GO
CC	GO:0043235	receptor complex	IEP	Predicted GO
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Predicted GO
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
BP	GO:0051239	regulation of multicellular organismal process	IEP	Predicted GO
BP	GO:0051241	negative regulation of multicellular organismal process	IEP	Predicted GO
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0052646	alditol phosphate metabolic process	IEP	Predicted GO
CC	GO:0098797	plasma membrane protein complex	IEP	Predicted GO
CC	GO:0098802	plasma membrane receptor complex	IEP	Predicted GO
BP	GO:0120009	intermembrane lipid transfer	IEP	Predicted GO
MF	GO:0120013	intermembrane lipid transfer activity	IEP	Predicted GO
BP	GO:1902298	cell cycle DNA replication maintenance of fidelity	IEP	Predicted GO
CC	GO:1902495	transmembrane transporter complex	IEP	Predicted GO
CC	GO:1990351	transporter complex	IEP	Predicted GO
BP	GO:1990426	mitotic recombination-dependent replication fork processing	IEP	Predicted GO
BP	GO:1990505	mitotic DNA replication maintenance of fidelity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001272	PEP_carboxykinase_ATP	68	536

External Links

PlasmoDB	814201
PlasmoDB	PF13_0234

PF3D7_1342800 (PEPCK)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation