PF3D7_1349300 (TKL3)

Aliases : TKL3

Description : SSF47769: Sterile alpha motif/pointed domain superfamily, SSF56112: Protein kinase-like domain superfamily. Pfam domain(s): PF07647: SAM domain (Sterile alpha motif), PF07714: Protein tyrosine kinase.

Gene families : OG_01_0003161 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0003161_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1349300
Cluster	P. falciparum: Cluster_49

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1362100	TKL3	SSF47769: Sterile alpha motif/pointed domain...	0.08	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004672	protein kinase activity	IDA	PlasmoDB
MF	GO:0004672	protein kinase activity	IEA	Interproscan predictions
MF	GO:0004672	protein kinase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan predictions
MF	GO:0005515	protein binding	IEA	PlasmoDB
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IDA	PlasmoDB
CC	GO:0005856	cytoskeleton	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	IDA	PlasmoDB
BP	GO:0006468	protein phosphorylation	IEA	Interproscan predictions
BP	GO:0006468	protein phosphorylation	IEA	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
CC	GO:0015630	microtubule cytoskeleton	IDA	PlasmoDB
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004383	guanylate cyclase activity	IEP	Predicted GO
MF	GO:0004806	triglyceride lipase activity	IEP	Predicted GO
MF	GO:0005516	calmodulin binding	IEP	Predicted GO
CC	GO:0005770	late endosome	IEP	Predicted GO
BP	GO:0006182	cGMP biosynthetic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006914	autophagy	IEP	Predicted GO
BP	GO:0009187	cyclic nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009190	cyclic nucleotide biosynthetic process	IEP	Predicted GO
MF	GO:0009975	cyclase activity	IEP	Predicted GO
BP	GO:0015977	carbon fixation	IEP	Predicted GO
MF	GO:0016303	1-phosphatidylinositol-3-kinase activity	IEP	Predicted GO
MF	GO:0016829	lyase activity	IEP	Predicted GO
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Predicted GO
MF	GO:0016984	ribulose-bisphosphate carboxylase activity	IEP	Predicted GO
MF	GO:0030492	hemoglobin binding	IEP	Predicted GO
MF	GO:0035004	phosphatidylinositol 3-kinase activity	IEP	Predicted GO
CC	GO:0043656	intracellular region of host	IEP	Predicted GO
BP	GO:0046068	cGMP metabolic process	IEP	Predicted GO
BP	GO:0051301	cell division	IEP	Predicted GO
BP	GO:0052652	cyclic purine nucleotide metabolic process	IEP	Predicted GO
MF	GO:0052742	phosphatidylinositol kinase activity	IEP	Predicted GO
BP	GO:0061919	process utilizing autophagic mechanism	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001660	SAM	1312	1365
IPR001245	Ser-Thr/Tyr_kinase_cat_dom	1570	1786

External Links

PlasmoDB	814223
PlasmoDB	PF13_0258

PF3D7_1349300 (TKL3)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation