PF3D7_1356900 (PK5)

Aliases : PK5

Description : SSF56112: Protein kinase-like domain superfamily. Pfam domain(s): PF00069: Protein kinase domain.

Gene families : OG_01_0000081 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000081_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1356900
Cluster	P. falciparum: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1133200	CRK2	SSF56112: Protein kinase-like domain superfamily. Pfam...	0.06	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004672	protein kinase activity	IEA	Interproscan predictions
MF	GO:0004672	protein kinase activity	IEA	PlasmoDB
MF	GO:0004674	protein serine/threonine kinase activity	None	Extended
MF	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IDA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IDA	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	IDA	PlasmoDB
BP	GO:0006468	protein phosphorylation	IEA	Interproscan predictions
BP	GO:0006468	protein phosphorylation	IEA	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0007049	cell cycle	ISS	PlasmoDB
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0060089	molecular transducer activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0097472	cyclin-dependent protein kinase activity	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000225	N-acetylglucosaminylphosphatidylinositol deacetylase activity	IEP	Predicted GO
CC	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Predicted GO
CC	GO:0000315	organellar large ribosomal subunit	IEP	Predicted GO
CC	GO:0000932	P-body	IEP	Predicted GO
BP	GO:0003006	developmental process involved in reproduction	IEP	Predicted GO
MF	GO:0003689	DNA clamp loader activity	IEP	Predicted GO
MF	GO:0003729	mRNA binding	IEP	Predicted GO
MF	GO:0003998	acylphosphatase activity	IEP	Predicted GO
MF	GO:0004170	dUTP diphosphatase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004311	farnesyltranstransferase activity	IEP	Predicted GO
MF	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IEP	Predicted GO
MF	GO:0004354	glutamate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004550	nucleoside diphosphate kinase activity	IEP	Predicted GO
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Predicted GO
MF	GO:0004774	succinate-CoA ligase activity	IEP	Predicted GO
MF	GO:0004775	succinate-CoA ligase (ADP-forming) activity	IEP	Predicted GO
MF	GO:0004791	thioredoxin-disulfide reductase activity	IEP	Predicted GO
MF	GO:0005483	soluble NSF attachment protein activity	IEP	Predicted GO
CC	GO:0005663	DNA replication factor C complex	IEP	Predicted GO
CC	GO:0005672	transcription factor TFIIA complex	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005756	mitochondrial proton-transporting ATP synthase, central stalk	IEP	Predicted GO
CC	GO:0005763	mitochondrial small ribosomal subunit	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
CC	GO:0005868	cytoplasmic dynein complex	IEP	Predicted GO
BP	GO:0006104	succinyl-CoA metabolic process	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006183	GTP biosynthetic process	IEP	Predicted GO
BP	GO:0006228	UTP biosynthetic process	IEP	Predicted GO
BP	GO:0006241	CTP biosynthetic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	Predicted GO
BP	GO:0006271	DNA strand elongation involved in DNA replication	IEP	Predicted GO
BP	GO:0006272	leading strand elongation	IEP	Predicted GO
BP	GO:0006378	mRNA polyadenylation	IEP	Predicted GO
BP	GO:0006497	protein lipidation	IEP	Predicted GO
BP	GO:0006505	GPI anchor metabolic process	IEP	Predicted GO
BP	GO:0006506	GPI anchor biosynthetic process	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006537	glutamate biosynthetic process	IEP	Predicted GO
BP	GO:0006643	membrane lipid metabolic process	IEP	Predicted GO
BP	GO:0006650	glycerophospholipid metabolic process	IEP	Predicted GO
BP	GO:0006661	phosphatidylinositol biosynthetic process	IEP	Predicted GO
BP	GO:0006664	glycolipid metabolic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0006783	heme biosynthetic process	IEP	Predicted GO
BP	GO:0006784	heme a biosynthetic process	IEP	Predicted GO
BP	GO:0006790	sulfur compound metabolic process	IEP	Predicted GO
BP	GO:0007530	sex determination	IEP	Predicted GO
MF	GO:0008495	protoheme IX farnesyltransferase activity	IEP	Predicted GO
BP	GO:0008535	respiratory chain complex IV assembly	IEP	Predicted GO
BP	GO:0008654	phospholipid biosynthetic process	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009247	glycolipid biosynthetic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
CC	GO:0009376	HslUV protease complex	IEP	Predicted GO
BP	GO:0010035	response to inorganic substance	IEP	Predicted GO
BP	GO:0010038	response to metal ion	IEP	Predicted GO
MF	GO:0015035	protein disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015037	peptide disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015038	glutathione disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	IEP	Predicted GO
MF	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	IEP	Predicted GO
MF	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
BP	GO:0017004	cytochrome complex assembly	IEP	Predicted GO
MF	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	IEP	Predicted GO
CC	GO:0019005	SCF ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0019153	protein-disulfide reductase (glutathione) activity	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
CC	GO:0019774	proteasome core complex, beta-subunit complex	IEP	Predicted GO
MF	GO:0019787	ubiquitin-like protein transferase activity	IEP	Predicted GO
MF	GO:0019788	NEDD8 transferase activity	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0022414	reproductive process	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
BP	GO:0022616	DNA strand elongation	IEP	Predicted GO
CC	GO:0030121	AP-1 adaptor complex	IEP	Predicted GO
BP	GO:0031124	mRNA 3'-end processing	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0031597	cytosolic proteasome complex	IEP	Predicted GO
BP	GO:0032446	protein modification by small protein conjugation	IEP	Predicted GO
MF	GO:0032552	deoxyribonucleotide binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Predicted GO
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Predicted GO
MF	GO:0033170	protein-DNA loading ATPase activity	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
CC	GO:0035145	exon-exon junction complex	IEP	Predicted GO
BP	GO:0042168	heme metabolic process	IEP	Predicted GO
BP	GO:0042440	pigment metabolic process	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
CC	GO:0043186	P granule	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044451	nucleoplasm part	IEP	Predicted GO
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Predicted GO
BP	GO:0045116	protein neddylation	IEP	Predicted GO
CC	GO:0045269	proton-transporting ATP synthase, central stalk	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0046036	CTP metabolic process	IEP	Predicted GO
BP	GO:0046039	GTP metabolic process	IEP	Predicted GO
BP	GO:0046051	UTP metabolic process	IEP	Predicted GO
BP	GO:0046148	pigment biosynthetic process	IEP	Predicted GO
BP	GO:0046160	heme a metabolic process	IEP	Predicted GO
BP	GO:0046467	membrane lipid biosynthetic process	IEP	Predicted GO
BP	GO:0046474	glycerophospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0046486	glycerolipid metabolic process	IEP	Predicted GO
BP	GO:0046488	phosphatidylinositol metabolic process	IEP	Predicted GO
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Predicted GO
BP	GO:0048033	heme o metabolic process	IEP	Predicted GO
BP	GO:0048034	heme O biosynthetic process	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051382	kinetochore assembly	IEP	Predicted GO
BP	GO:0051383	kinetochore organization	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
CC	GO:0098798	mitochondrial protein complex	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901070	guanosine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1903509	liposaccharide metabolic process	IEP	Predicted GO
CC	GO:1990229	iron-sulfur cluster assembly complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000719	Prot_kinase_dom	4	284

External Links

PlasmoDB	813841
PlasmoDB	MAL13P1.279

PF3D7_1356900 (PK5)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation