PF3D7_1359300 (DIS3)

Aliases : DIS3

Description : SSF50249: "Nucleic acid-binding, OB-fold". Pfam domain(s): PF17849: Dis3-like cold-shock domain 2 (CSD2), PF00773: RNB domain.

Gene families : OG_01_0002898 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002898_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1359300
Cluster	P. falciparum: Cluster_40

Type	GO Term	Name	Evidence	Source
MF	GO:0000175	3'-5'-exoribonuclease activity	IDA	PlasmoDB
CC	GO:0000177	cytoplasmic exosome (RNase complex)	IDA	PlasmoDB
CC	GO:0000178	exosome (RNase complex)	IDA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	Interproscan predictions
MF	GO:0003723	RNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0004532	exoribonuclease activity	None	Extended
MF	GO:0004540	ribonuclease activity	IMP	PlasmoDB
MF	GO:0004540	ribonuclease activity	IEA	Interproscan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IDA	PlasmoDB
CC	GO:0005829	cytosol	IDA	PlasmoDB
MF	GO:0008408	3'-5' exonuclease activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	None	Extended
MF	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
CC	GO:0048471	perinuclear region of cytoplasm	IDA	PlasmoDB
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1905354	exoribonuclease complex	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0003724	RNA helicase activity	IEP	Predicted GO
MF	GO:0004004	ATP-dependent RNA helicase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006401	RNA catabolic process	IEP	Predicted GO
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
MF	GO:0008026	ATP-dependent helicase activity	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
MF	GO:0008186	RNA-dependent ATPase activity	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
MF	GO:0052381	tRNA dimethylallyltransferase activity	IEP	Predicted GO
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001900	RNase_II/R	595	936

External Links

PlasmoDB	813851
PlasmoDB	MAL13P1.289

PF3D7_1359300 (DIS3)

Expression Profile

Co-expression Networks

Functional Annotation