PF3D7_1361900 (PCNA1)

Aliases : PCNA1

Description : SSF55979: No description available. Pfam domain(s): PF02747: "Proliferating cell nuclear antigen, C-terminal domain", PF00705: "Proliferating cell nuclear antigen, N-terminal domain".

Gene families : OG_01_0001513 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001513_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1361900
Cluster	P. falciparum: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1137900	PCNA1	SSF55979: 20-02-2019. Pfam domain(s): PF02747:...	0.06	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IDA	PlasmoDB
BP	GO:0006275	regulation of DNA replication	IEA	Interproscan predictions
BP	GO:0006275	regulation of DNA replication	IEA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
MF	GO:0030234	enzyme regulator activity	None	Extended
MF	GO:0030337	DNA polymerase processivity factor activity	IEA	PlasmoDB
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051052	regulation of DNA metabolic process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000036	acyl carrier activity	IEP	Predicted GO
MF	GO:0000062	fatty-acyl-CoA binding	IEP	Predicted GO
MF	GO:0000225	N-acetylglucosaminylphosphatidylinositol deacetylase activity	IEP	Predicted GO
MF	GO:0000234	phosphoethanolamine N-methyltransferase activity	IEP	Predicted GO
CC	GO:0000502	proteasome complex	IEP	Predicted GO
MF	GO:0003689	DNA clamp loader activity	IEP	Predicted GO
MF	GO:0003756	protein disulfide isomerase activity	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0003909	DNA ligase activity	IEP	Predicted GO
MF	GO:0003911	DNA ligase (NAD+) activity	IEP	Predicted GO
MF	GO:0003998	acylphosphatase activity	IEP	Predicted GO
MF	GO:0004000	adenosine deaminase activity	IEP	Predicted GO
MF	GO:0004013	adenosylhomocysteinase activity	IEP	Predicted GO
MF	GO:0004170	dUTP diphosphatase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004222	metalloendopeptidase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004368	glycerol-3-phosphate dehydrogenase (quinone) activity	IEP	Predicted GO
MF	GO:0004372	glycine hydroxymethyltransferase activity	IEP	Predicted GO
MF	GO:0004448	isocitrate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004450	isocitrate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004602	glutathione peroxidase activity	IEP	Predicted GO
MF	GO:0004784	superoxide dismutase activity	IEP	Predicted GO
MF	GO:0004791	thioredoxin-disulfide reductase activity	IEP	Predicted GO
MF	GO:0004825	methionine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005342	organic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005385	zinc ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005483	soluble NSF attachment protein activity	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005663	DNA replication factor C complex	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005838	proteasome regulatory particle	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006102	isocitrate metabolic process	IEP	Predicted GO
BP	GO:0006116	NADH oxidation	IEP	Predicted GO
BP	GO:0006127	glycerophosphate shuttle	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006271	DNA strand elongation involved in DNA replication	IEP	Predicted GO
BP	GO:0006272	leading strand elongation	IEP	Predicted GO
BP	GO:0006410	obsolete transcription, RNA-dependent	IEP	Predicted GO
BP	GO:0006431	methionyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006458	'de novo' protein folding	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006545	glycine biosynthetic process	IEP	Predicted GO
BP	GO:0006563	L-serine metabolic process	IEP	Predicted GO
BP	GO:0006627	protein processing involved in protein targeting to mitochondrion	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006631	fatty acid metabolic process	IEP	Predicted GO
BP	GO:0006734	NADH metabolic process	IEP	Predicted GO
BP	GO:0006784	heme a biosynthetic process	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006829	zinc ion transport	IEP	Predicted GO
BP	GO:0006835	dicarboxylic acid transport	IEP	Predicted GO
BP	GO:0006979	response to oxidative stress	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
MF	GO:0008170	N-methyltransferase activity	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008509	anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0008535	respiratory chain complex IV assembly	IEP	Predicted GO
BP	GO:0008610	lipid biosynthetic process	IEP	Predicted GO
MF	GO:0008897	holo-[acyl-carrier-protein] synthase activity	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
MF	GO:0015140	malate transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015367	oxoglutarate:malate antiporter activity	IEP	Predicted GO
MF	GO:0015556	C4-dicarboxylate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015740	C4-dicarboxylate transport	IEP	Predicted GO
BP	GO:0015742	alpha-ketoglutarate transport	IEP	Predicted GO
BP	GO:0015743	malate transport	IEP	Predicted GO
BP	GO:0015849	organic acid transport	IEP	Predicted GO
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Predicted GO
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
BP	GO:0016485	protein processing	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016802	trialkylsulfonium hydrolase activity	IEP	Predicted GO
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEP	Predicted GO
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Predicted GO
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Predicted GO
MF	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	IEP	Predicted GO
BP	GO:0017004	cytochrome complex assembly	IEP	Predicted GO
BP	GO:0017038	protein import	IEP	Predicted GO
BP	GO:0017062	respiratory chain complex III assembly	IEP	Predicted GO
CC	GO:0017087	mitochondrial processing peptidase complex	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0018143	nucleic acid-protein covalent cross-linking	IEP	Predicted GO
BP	GO:0018144	RNA-protein covalent cross-linking	IEP	Predicted GO
CC	GO:0019005	SCF ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0019239	deaminase activity	IEP	Predicted GO
BP	GO:0019264	glycine biosynthetic process from serine	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019674	NAD metabolic process	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
BP	GO:0022616	DNA strand elongation	IEP	Predicted GO
CC	GO:0030134	COPII-coated ER to Golgi transport vesicle	IEP	Predicted GO
MF	GO:0030604	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	IEP	Predicted GO
MF	GO:0031079	obsolete picornain 3C activity	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033108	mitochondrial respiratory chain complex assembly	IEP	Predicted GO
MF	GO:0033170	protein-DNA loading ATPase activity	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0034308	primary alcohol metabolic process	IEP	Predicted GO
BP	GO:0034551	mitochondrial respiratory chain complex III assembly	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034982	mitochondrial protein processing	IEP	Predicted GO
BP	GO:0035999	tetrahydrofolate interconversion	IEP	Predicted GO
BP	GO:0042136	neurotransmitter biosynthetic process	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
CC	GO:0043626	PCNA complex	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
MF	GO:0044620	ACP phosphopantetheine attachment site binding	IEP	Predicted GO
CC	GO:0044796	DNA polymerase processivity factor complex	IEP	Predicted GO
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Predicted GO
BP	GO:0045116	protein neddylation	IEP	Predicted GO
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0046160	heme a metabolic process	IEP	Predicted GO
BP	GO:0046416	D-amino acid metabolic process	IEP	Predicted GO
BP	GO:0046474	glycerophospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0046942	carboxylic acid transport	IEP	Predicted GO
MF	GO:0046943	carboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0051131	chaperone-mediated protein complex assembly	IEP	Predicted GO
MF	GO:0051192	prosthetic group binding	IEP	Predicted GO
BP	GO:0051382	kinetochore assembly	IEP	Predicted GO
BP	GO:0051383	kinetochore organization	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051604	protein maturation	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0061025	membrane fusion	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
BP	GO:0070070	proton-transporting V-type ATPase complex assembly	IEP	Predicted GO
BP	GO:0070071	proton-transporting two-sector ATPase complex assembly	IEP	Predicted GO
BP	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	IEP	Predicted GO
BP	GO:0070178	D-serine metabolic process	IEP	Predicted GO
MF	GO:0070402	NADPH binding	IEP	Predicted GO
MF	GO:0070628	proteasome binding	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
CC	GO:0071944	cell periphery	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
MF	GO:1901567	fatty acid derivative binding	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
CC	GO:1905369	endopeptidase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR022648	Pr_cel_nuc_antig_N	1	125
IPR022649	Pr_cel_nuc_antig_C	128	246

External Links

PlasmoDB	814288
PlasmoDB	PF13_0328

PF3D7_1361900 (PCNA1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation