PF3D7_1364300 (PRP16)

Aliases : PRP16

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF00271: Helicase conserved C-terminal domain, PF04408: Helicase associated domain (HA2), PF07717: Oligonucleotide/oligosaccharide-binding (OB)-fold, PF00270: DEAD/DEAH box helicase.

Gene families : OG_01_0000023 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000023_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1364300
Cluster	P. falciparum: Cluster_36

Target	Alias	Description	ECC score	Gene Family Method
PBANKA_0514100	PRP22	SSF50249: Nucleic acid-binding, OB-fold, SSF52540:...	0.03	Orthofinderv1.1.8
PBANKA_0818600	PRP43	SSF52540: P-loop containing nucleoside triphosphate...	0.02	Orthofinderv1.1.8
PBANKA_1140200	PRP16	SSF52540: P-loop containing nucleoside triphosphate...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
BP	GO:0000375	RNA splicing, via transesterification reactions	ISS	PlasmoDB
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	None	Extended
BP	GO:0000398	mRNA splicing, via spliceosome	ISS	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan predictions
MF	GO:0003676	nucleic acid binding	IEA	PlasmoDB
MF	GO:0003724	RNA helicase activity	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004004	ATP-dependent RNA helicase activity	IDA	PlasmoDB
MF	GO:0004386	helicase activity	IEA	Interproscan predictions
MF	GO:0004386	helicase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IDA	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006397	mRNA processing	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008026	ATP-dependent helicase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008186	RNA-dependent ATPase activity	None	Extended
BP	GO:0008380	RNA splicing	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016071	mRNA metabolic process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0070035	purine NTP-dependent helicase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
CC	GO:0000172	ribonuclease MRP complex	IEP	Predicted GO
BP	GO:0000966	RNA 5'-end processing	IEP	Predicted GO
BP	GO:0001510	RNA methylation	IEP	Predicted GO
BP	GO:0001682	tRNA 5'-leader removal	IEP	Predicted GO
MF	GO:0004221	obsolete ubiquitin thiolesterase activity	IEP	Predicted GO
MF	GO:0004526	ribonuclease P activity	IEP	Predicted GO
MF	GO:0004549	tRNA-specific ribonuclease activity	IEP	Predicted GO
MF	GO:0004713	protein tyrosine kinase activity	IEP	Predicted GO
MF	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEP	Predicted GO
MF	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0004888	transmembrane signaling receptor activity	IEP	Predicted GO
CC	GO:0005666	RNA polymerase III complex	IEP	Predicted GO
CC	GO:0005882	intermediate filament	IEP	Predicted GO
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0007166	cell surface receptor signaling pathway	IEP	Predicted GO
BP	GO:0007167	enzyme linked receptor protein signaling pathway	IEP	Predicted GO
BP	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
MF	GO:0008173	RNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008174	mRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008175	tRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
MF	GO:0010181	FMN binding	IEP	Predicted GO
MF	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
MF	GO:0019199	transmembrane receptor protein kinase activity	IEP	Predicted GO
BP	GO:0030488	tRNA methylation	IEP	Predicted GO
CC	GO:0030677	ribonuclease P complex	IEP	Predicted GO
MF	GO:0031625	ubiquitin protein ligase binding	IEP	Predicted GO
CC	GO:0031965	nuclear membrane	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034471	ncRNA 5'-end processing	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
MF	GO:0038023	signaling receptor activity	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
MF	GO:0044389	ubiquitin-like protein ligase binding	IEP	Predicted GO
CC	GO:0045095	keratin filament	IEP	Predicted GO
MF	GO:0060089	molecular transducer activity	IEP	Predicted GO
BP	GO:0099116	tRNA 5'-end processing	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
CC	GO:1902555	endoribonuclease complex	IEP	Predicted GO
CC	GO:1905348	endonuclease complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001650	Helicase_C	772	858
IPR007502	Helicase-assoc_dom	921	1008
IPR011709	DUF1605	1066	1143
IPR011545	DEAD/DEAH_box_helicase_dom	487	637

External Links

PlasmoDB	813888
PlasmoDB	MAL13P1.322

PF3D7_1364300 (PRP16)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation