PF3D7_1364800 (RPB5)

Aliases : RPB5

Description : SSF53036: "RNA polymerase Rpb5, N-terminal domain superfamily", SSF55287: RPB5-like RNA polymerase subunit superfamily. Pfam domain(s): PF03871: "RNA polymerase Rpb5, N-terminal domain", PF01191: "RNA polymerase Rpb5, C-terminal domain".

Gene families : OG_01_0001527 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001527_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1364800
Cluster	P. falciparum: Cluster_11

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1140600	RPB5	SSF55287: RPB5-like RNA polymerase subunit superfamily,...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	ISM	PlasmoDB
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	ISM	PlasmoDB
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEA	Interproscan predictions
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan predictions
CC	GO:0005634	nucleus	IEA	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006351	transcription, DNA-templated	IEA	Interproscan predictions
BP	GO:0006351	transcription, DNA-templated	IEA	PlasmoDB
BP	GO:0006366	transcription by RNA polymerase II	ISS	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0032774	RNA biosynthetic process	None	Extended
MF	GO:0034062	5'-3' RNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:0097659	nucleic acid-templated transcription	None	Extended
MF	GO:0097747	RNA polymerase activity	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000323	lytic vacuole	IEP	Predicted GO
MF	GO:0000339	RNA cap binding	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000380	alternative mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003727	single-stranded RNA binding	IEP	Predicted GO
MF	GO:0003729	mRNA binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003938	IMP dehydrogenase activity	IEP	Predicted GO
MF	GO:0004081	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity	IEP	Predicted GO
MF	GO:0004356	glutamate-ammonia ligase activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004457	lactate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004459	L-lactate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004551	nucleotide diphosphatase activity	IEP	Predicted GO
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005381	iron ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005730	nucleolus	IEP	Predicted GO
CC	GO:0005764	lysosome	IEP	Predicted GO
CC	GO:0005767	secondary lysosome	IEP	Predicted GO
CC	GO:0005773	vacuole	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005851	eukaryotic translation initiation factor 2B complex	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006541	glutamine metabolic process	IEP	Predicted GO
BP	GO:0006542	glutamine biosynthetic process	IEP	Predicted GO
BP	GO:0006857	oligopeptide transport	IEP	Predicted GO
MF	GO:0008097	5S rRNA binding	IEP	Predicted GO
MF	GO:0008187	poly-pyrimidine tract binding	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
MF	GO:0008452	RNA ligase activity	IEP	Predicted GO
MF	GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity	IEP	Predicted GO
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Predicted GO
MF	GO:0009678	hydrogen-translocating pyrophosphatase activity	IEP	Predicted GO
MF	GO:0015091	ferric iron transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015093	ferrous iron transmembrane transporter activity	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
CC	GO:0015935	small ribosomal subunit	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
MF	GO:0016211	ammonia ligase activity	IEP	Predicted GO
CC	GO:0016281	eukaryotic translation initiation factor 4F complex	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016880	acid-ammonia (or amide) ligase activity	IEP	Predicted GO
MF	GO:0019843	rRNA binding	IEP	Predicted GO
CC	GO:0020020	food vacuole	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
BP	GO:0022618	ribonucleoprotein complex assembly	IEP	Predicted GO
CC	GO:0022627	cytosolic small ribosomal subunit	IEP	Predicted GO
BP	GO:0030091	protein repair	IEP	Predicted GO
CC	GO:0030139	endocytic vesicle	IEP	Predicted GO
CC	GO:0030430	host cell cytoplasm	IEP	Predicted GO
MF	GO:0030621	U4 snRNA binding	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0032010	phagolysosome	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0033643	host cell part	IEP	Predicted GO
CC	GO:0033646	host intracellular part	IEP	Predicted GO
MF	GO:0033677	DNA/RNA helicase activity	IEP	Predicted GO
MF	GO:0033679	3'-5' DNA/RNA helicase activity	IEP	Predicted GO
CC	GO:0034457	Mpp10 complex	IEP	Predicted GO
MF	GO:0034511	U3 snoRNA binding	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0034635	glutathione transport	IEP	Predicted GO
MF	GO:0036524	protein deglycase activity	IEP	Predicted GO
BP	GO:0036525	protein deglycation	IEP	Predicted GO
BP	GO:0042255	ribosome assembly	IEP	Predicted GO
BP	GO:0042256	mature ribosome assembly	IEP	Predicted GO
BP	GO:0042273	ribosomal large subunit biogenesis	IEP	Predicted GO
BP	GO:0042939	tripeptide transport	IEP	Predicted GO
MF	GO:0043023	ribosomal large subunit binding	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043484	regulation of RNA splicing	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
CC	GO:0044164	host cell cytosol	IEP	Predicted GO
CC	GO:0044217	other organism part	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0045335	phagocytic vesicle	IEP	Predicted GO
BP	GO:0051181	cofactor transport	IEP	Predicted GO
BP	GO:0070925	organelle assembly	IEP	Predicted GO
BP	GO:0071826	ribonucleoprotein complex subunit organization	IEP	Predicted GO
BP	GO:0072337	modified amino acid transport	IEP	Predicted GO
BP	GO:0072348	sulfur compound transport	IEP	Predicted GO
MF	GO:0072509	divalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0072510	trivalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR005571	RNA_pol_Rpb5_N	3	89
IPR000783	RNA_pol_subH/Rpb5_C	132	204

External Links

PlasmoDB	814300
PlasmoDB	PF13_0341

PF3D7_1364800 (RPB5)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation