PF3D7_1368100 (RPN11)

Aliases : RPN11

Description : SSF102712: No description available. Pfam domain(s): PF13012: Maintenance of mitochondrial structure and function, PF01398: JAB1/Mov34/MPN/PAD-1 ubiquitin protease.

Gene families : OG_01_0001544 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001544_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1368100
Cluster	P. falciparum: Cluster_30

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan predictions
MF	GO:0005515	protein binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005838	proteasome regulatory particle	ISS	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	ISS	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
CC	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	IEP	Predicted GO
CC	GO:0000323	lytic vacuole	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003785	actin monomer binding	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0003863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	IEP	Predicted GO
MF	GO:0003924	GTPase activity	IEP	Predicted GO
MF	GO:0004129	cytochrome-c oxidase activity	IEP	Predicted GO
MF	GO:0004402	histone acetyltransferase activity	IEP	Predicted GO
MF	GO:0004475	mannose-1-phosphate guanylyltransferase activity	IEP	Predicted GO
MF	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005750	mitochondrial respiratory chain complex III	IEP	Predicted GO
CC	GO:0005764	lysosome	IEP	Predicted GO
CC	GO:0005767	secondary lysosome	IEP	Predicted GO
CC	GO:0005851	eukaryotic translation initiation factor 2B complex	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	IEP	Predicted GO
BP	GO:0006405	RNA export from nucleus	IEP	Predicted GO
BP	GO:0006471	protein ADP-ribosylation	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006825	copper ion transport	IEP	Predicted GO
BP	GO:0006873	cellular ion homeostasis	IEP	Predicted GO
BP	GO:0006885	regulation of pH	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
BP	GO:0007035	vacuolar acidification	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008121	ubiquinol-cytochrome-c reductase activity	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
MF	GO:0008521	acetyl-CoA transmembrane transporter activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
MF	GO:0008905	mannose-phosphate guanylyltransferase activity	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009060	aerobic respiration	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009225	nucleotide-sugar metabolic process	IEP	Predicted GO
BP	GO:0009226	nucleotide-sugar biosynthetic process	IEP	Predicted GO
BP	GO:0009298	GDP-mannose biosynthetic process	IEP	Predicted GO
MF	GO:0015002	heme-copper terminal oxidase activity	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015095	magnesium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015215	nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015216	purine nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Predicted GO
CC	GO:0015629	actin cytoskeleton	IEP	Predicted GO
BP	GO:0015672	monovalent inorganic cation transport	IEP	Predicted GO
BP	GO:0015693	magnesium ion transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
BP	GO:0015980	energy derivation by oxidation of organic compounds	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
CC	GO:0016282	eukaryotic 43S preinitiation complex	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	IEP	Predicted GO
MF	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	IEP	Predicted GO
MF	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0019673	GDP-mannose metabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
MF	GO:0019829	cation-transporting ATPase activity	IEP	Predicted GO
CC	GO:0020020	food vacuole	IEP	Predicted GO
CC	GO:0022625	cytosolic large ribosomal subunit	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022853	active ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0030001	metal ion transport	IEP	Predicted GO
BP	GO:0030003	cellular cation homeostasis	IEP	Predicted GO
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0030036	actin cytoskeleton organization	IEP	Predicted GO
BP	GO:0030048	actin filament-based movement	IEP	Predicted GO
CC	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0030139	endocytic vesicle	IEP	Predicted GO
BP	GO:0030641	regulation of cellular pH	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0032010	phagolysosome	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Predicted GO
CC	GO:0033180	proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
MF	GO:0034212	peptide N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
MF	GO:0036442	proton-exporting ATPase activity	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
MF	GO:0042625	ATPase coupled ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
CC	GO:0044437	vacuolar part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
MF	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0045275	respiratory chain complex III	IEP	Predicted GO
BP	GO:0045333	cellular respiration	IEP	Predicted GO
CC	GO:0045335	phagocytic vesicle	IEP	Predicted GO
BP	GO:0045851	pH reduction	IEP	Predicted GO
BP	GO:0046034	ATP metabolic process	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
MF	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
BP	GO:0050657	nucleic acid transport	IEP	Predicted GO
BP	GO:0050658	RNA transport	IEP	Predicted GO
BP	GO:0050801	ion homeostasis	IEP	Predicted GO
BP	GO:0051014	actin filament severing	IEP	Predicted GO
BP	GO:0051168	nuclear export	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
MF	GO:0051184	cofactor transmembrane transporter activity	IEP	Predicted GO
MF	GO:0051185	coenzyme transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
BP	GO:0051236	establishment of RNA localization	IEP	Predicted GO
BP	GO:0051262	protein tetramerization	IEP	Predicted GO
BP	GO:0051302	regulation of cell division	IEP	Predicted GO
BP	GO:0051452	intracellular pH reduction	IEP	Predicted GO
BP	GO:0051453	regulation of intracellular pH	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
BP	GO:0055067	monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0055080	cation homeostasis	IEP	Predicted GO
BP	GO:0055082	cellular chemical homeostasis	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0060327	cytoplasmic actin-based contraction involved in cell motility	IEP	Predicted GO
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0065007	biological regulation	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
CC	GO:0070069	cytochrome complex	IEP	Predicted GO
BP	GO:0070252	actin-mediated cell contraction	IEP	Predicted GO
MF	GO:0070568	guanylyltransferase activity	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0070838	divalent metal ion transport	IEP	Predicted GO
CC	GO:0070993	translation preinitiation complex	IEP	Predicted GO
MF	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
CC	GO:0089701	U2AF	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
BP	GO:0098655	cation transmembrane transport	IEP	Predicted GO
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Predicted GO
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Predicted GO
BP	GO:0098771	inorganic ion homeostasis	IEP	Predicted GO
CC	GO:0098796	membrane protein complex	IEP	Predicted GO
CC	GO:0098798	mitochondrial protein complex	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
MF	GO:1901682	sulfur compound transmembrane transporter activity	IEP	Predicted GO
BP	GO:1902600	proton transmembrane transport	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR024969	Rpn11/EIF3F_C	175	282
IPR000555	JAMM/MPN+_dom	29	140

External Links

PlasmoDB	813911
PlasmoDB	MAL13P1.343

PF3D7_1368100 (RPN11)

Expression Profile

Co-expression Networks

Functional Annotation