PF3D7_1405400 (MutS)

Aliases : MutS

Description : SSF55271: "DNA mismatch repair protein MutS, N-terminal", SSF52540: P-loop containing nucleoside triphosphate hydrolase, SSF82771: GIY-YIG endonuclease superfamily. Pfam domain(s): PF01624: MutS domain I, PF00488: MutS domain V.

Gene families : OG_01_0001351 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001351_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1405400
Cluster	P. falciparum: Cluster_14

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1036800	MutS	SSF52540: P-loop containing nucleoside triphosphate...	0.05	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan predictions
BP	GO:0006298	mismatch repair	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
CC	GO:0020011	apicoplast	RCA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan predictions
MF	GO:0030983	mismatched DNA binding	IEA	PlasmoDB
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEP	Predicted GO
MF	GO:0003721	telomerase RNA reverse transcriptase activity	IEP	Predicted GO
MF	GO:0003964	RNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0004179	obsolete membrane alanyl aminopeptidase activity	IEP	Predicted GO
MF	GO:0004518	nuclease activity	IEP	Predicted GO
MF	GO:0004519	endonuclease activity	IEP	Predicted GO
MF	GO:0004523	RNA-DNA hybrid ribonuclease activity	IEP	Predicted GO
MF	GO:0004527	exonuclease activity	IEP	Predicted GO
MF	GO:0004822	isoleucine-tRNA ligase activity	IEP	Predicted GO
BP	GO:0006278	RNA-dependent DNA biosynthetic process	IEP	Predicted GO
BP	GO:0006428	isoleucyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0007004	telomere maintenance via telomerase	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
MF	GO:0009982	pseudouridine synthase activity	IEP	Predicted GO
BP	GO:0010833	telomere maintenance via telomere lengthening	IEP	Predicted GO
BP	GO:0015074	DNA integration	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
BP	GO:0016441	posttranscriptional gene silencing	IEP	Predicted GO
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Predicted GO
MF	GO:0016866	intramolecular transferase activity	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
BP	GO:0032196	transposition	IEP	Predicted GO
BP	GO:0032202	telomere assembly	IEP	Predicted GO
BP	GO:0032203	telomere formation via telomerase	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
BP	GO:0040029	regulation of gene expression, epigenetic	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000432	DNA_mismatch_repair_MutS_C	1053	1242
IPR007695	DNA_mismatch_repair_MutS-lik_N	218	312

External Links

PlasmoDB	811633
PlasmoDB	PF14_0051

PF3D7_1405400 (MutS)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation