PF3D7_1408400 (FANCJ)

Aliases : FANCJ

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF06733: DEAD_2, PF13307: Helicase C-terminal domain.

Gene families : OG_01_0001335 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001335_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1408400
Cluster	P. falciparum: Cluster_40

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1034100	FANCJ	SSF52540: P-loop containing nucleoside triphosphate...	0.06	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan predictions
MF	GO:0003676	nucleic acid binding	IEA	PlasmoDB
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003678	DNA helicase activity	None	Extended
MF	GO:0003678	DNA helicase activity	ISS	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004003	ATP-dependent DNA helicase activity	IEA	Interproscan predictions
MF	GO:0004003	ATP-dependent DNA helicase activity	IEA	PlasmoDB
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	Interproscan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008026	ATP-dependent helicase activity	IEA	Interproscan predictions
MF	GO:0008026	ATP-dependent helicase activity	IEA	PlasmoDB
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEA	Interproscan predictions
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEA	PlasmoDB
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0070035	purine NTP-dependent helicase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000075	cell cycle checkpoint	IEP	Predicted GO
BP	GO:0000076	DNA replication checkpoint	IEP	Predicted GO
BP	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEP	Predicted GO
CC	GO:0000796	condensin complex	IEP	Predicted GO
CC	GO:0000799	nuclear condensin complex	IEP	Predicted GO
CC	GO:0000808	origin recognition complex	IEP	Predicted GO
CC	GO:0000922	spindle pole	IEP	Predicted GO
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	IEP	Predicted GO
MF	GO:0003688	DNA replication origin binding	IEP	Predicted GO
MF	GO:0003690	double-stranded DNA binding	IEP	Predicted GO
MF	GO:0004435	phosphatidylinositol phospholipase C activity	IEP	Predicted GO
MF	GO:0004529	exodeoxyribonuclease activity	IEP	Predicted GO
MF	GO:0004620	phospholipase activity	IEP	Predicted GO
MF	GO:0004629	phospholipase C activity	IEP	Predicted GO
MF	GO:0005102	signaling receptor binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005657	replication fork	IEP	Predicted GO
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
CC	GO:0005815	microtubule organizing center	IEP	Predicted GO
CC	GO:0005856	cytoskeleton	IEP	Predicted GO
CC	GO:0005874	microtubule	IEP	Predicted GO
CC	GO:0005938	cell cortex	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006323	DNA packaging	IEP	Predicted GO
BP	GO:0006402	mRNA catabolic process	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
BP	GO:0007017	microtubule-based process	IEP	Predicted GO
BP	GO:0007020	microtubule nucleation	IEP	Predicted GO
BP	GO:0007049	cell cycle	IEP	Predicted GO
BP	GO:0007076	mitotic chromosome condensation	IEP	Predicted GO
BP	GO:0007165	signal transduction	IEP	Predicted GO
BP	GO:0007275	multicellular organism development	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008296	3'-5'-exodeoxyribonuclease activity	IEP	Predicted GO
MF	GO:0008297	single-stranded DNA exodeoxyribonuclease activity	IEP	Predicted GO
MF	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity	IEP	Predicted GO
MF	GO:0015631	tubulin binding	IEP	Predicted GO
MF	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
CC	GO:0030014	CCR4-NOT complex	IEP	Predicted GO
BP	GO:0030154	cell differentiation	IEP	Predicted GO
BP	GO:0030261	chromosome condensation	IEP	Predicted GO
BP	GO:0031570	DNA integrity checkpoint	IEP	Predicted GO
BP	GO:0032065	cortical protein anchoring	IEP	Predicted GO
BP	GO:0032501	multicellular organismal process	IEP	Predicted GO
BP	GO:0032507	maintenance of protein location in cell	IEP	Predicted GO
MF	GO:0042162	telomeric DNA binding	IEP	Predicted GO
CC	GO:0042575	DNA polymerase complex	IEP	Predicted GO
MF	GO:0043015	gamma-tubulin binding	IEP	Predicted GO
CC	GO:0043625	delta DNA polymerase complex	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044454	nuclear chromosome part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0045185	maintenance of protein location	IEP	Predicted GO
BP	GO:0045786	negative regulation of cell cycle	IEP	Predicted GO
BP	GO:0048519	negative regulation of biological process	IEP	Predicted GO
BP	GO:0048856	anatomical structure development	IEP	Predicted GO
BP	GO:0048869	cellular developmental process	IEP	Predicted GO
BP	GO:0051235	maintenance of location	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0051301	cell division	IEP	Predicted GO
BP	GO:0051651	maintenance of location in cell	IEP	Predicted GO
CC	GO:0099080	supramolecular complex	IEP	Predicted GO
CC	GO:0099081	supramolecular polymer	IEP	Predicted GO
CC	GO:0099512	supramolecular fiber	IEP	Predicted GO
CC	GO:0099513	polymeric cytoskeletal fiber	IEP	Predicted GO
CC	GO:0099568	cytoplasmic region	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR010614	DEAD_2	126	299
IPR006555	ATP-dep_Helicase_C	634	825

External Links

PlasmoDB	811663
PlasmoDB	PF14_0081

PF3D7_1408400 (FANCJ)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation