Aliases : eIF2gamma
Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase, SSF50465: "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal", SSF50447: "Translation protein, beta-barrel domain superfamily". Pfam domain(s): PF03144: Elongation factor Tu domain 2, PF00009: Elongation factor Tu GTP binding domain, PF09173: "Initiation factor eIF2 gamma, C terminal".
Gene families : OG_01_0001327 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001327_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pfa RNA-seq: PF3D7_1410600 | |
Cluster | P. falciparum: Cluster_34 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
PBANKA_1031900 | eIF2gamma | SSF50447: Translation protein, beta-barrel domain... | 0.09 | Orthofinderv1.1.8 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003743 | translation initiation factor activity | ISS | PlasmoDB |
MF | GO:0003924 | GTPase activity | IEA | Interproscan predictions |
MF | GO:0003924 | GTPase activity | IEA | PlasmoDB |
MF | GO:0005515 | protein binding | IPI | PlasmoDB |
MF | GO:0005525 | GTP binding | ISS | PlasmoDB |
MF | GO:0005525 | GTP binding | IEA | Interproscan predictions |
MF | GO:0005525 | GTP binding | IEA | PlasmoDB |
CC | GO:0005850 | eukaryotic translation initiation factor 2 complex | ISS | PlasmoDB |
BP | GO:0006413 | translational initiation | ISS | PlasmoDB |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000182 | rDNA binding | IEP | Predicted GO |
MF | GO:0000287 | magnesium ion binding | IEP | Predicted GO |
MF | GO:0000339 | RNA cap binding | IEP | Predicted GO |
BP | GO:0000375 | RNA splicing, via transesterification reactions | IEP | Predicted GO |
BP | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | IEP | Predicted GO |
BP | GO:0000380 | alternative mRNA splicing, via spliceosome | IEP | Predicted GO |
BP | GO:0000398 | mRNA splicing, via spliceosome | IEP | Predicted GO |
CC | GO:0000428 | DNA-directed RNA polymerase complex | IEP | Predicted GO |
MF | GO:0000900 | translation repressor activity, mRNA regulatory element binding | IEP | Predicted GO |
BP | GO:0001678 | cellular glucose homeostasis | IEP | Predicted GO |
BP | GO:0001731 | formation of translation preinitiation complex | IEP | Predicted GO |
MF | GO:0003677 | DNA binding | IEP | Predicted GO |
MF | GO:0003727 | single-stranded RNA binding | IEP | Predicted GO |
MF | GO:0003729 | mRNA binding | IEP | Predicted GO |
MF | GO:0003735 | structural constituent of ribosome | IEP | Predicted GO |
MF | GO:0003746 | translation elongation factor activity | IEP | Predicted GO |
MF | GO:0003872 | 6-phosphofructokinase activity | IEP | Predicted GO |
MF | GO:0003899 | DNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
MF | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity | IEP | Predicted GO |
MF | GO:0004081 | bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity | IEP | Predicted GO |
MF | GO:0004365 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | IEP | Predicted GO |
MF | GO:0004396 | hexokinase activity | IEP | Predicted GO |
MF | GO:0004551 | nucleotide diphosphatase activity | IEP | Predicted GO |
MF | GO:0004619 | phosphoglycerate mutase activity | IEP | Predicted GO |
MF | GO:0004743 | pyruvate kinase activity | IEP | Predicted GO |
MF | GO:0004749 | ribose phosphate diphosphokinase activity | IEP | Predicted GO |
MF | GO:0004812 | aminoacyl-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0004824 | lysine-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0004827 | proline-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0004828 | serine-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0005198 | structural molecule activity | IEP | Predicted GO |
MF | GO:0005536 | glucose binding | IEP | Predicted GO |
CC | GO:0005634 | nucleus | IEP | Predicted GO |
CC | GO:0005665 | RNA polymerase II, core complex | IEP | Predicted GO |
CC | GO:0005681 | spliceosomal complex | IEP | Predicted GO |
CC | GO:0005682 | U5 snRNP | IEP | Predicted GO |
CC | GO:0005685 | U1 snRNP | IEP | Predicted GO |
CC | GO:0005732 | small nucleolar ribonucleoprotein complex | IEP | Predicted GO |
CC | GO:0005829 | cytosol | IEP | Predicted GO |
CC | GO:0005840 | ribosome | IEP | Predicted GO |
CC | GO:0005853 | eukaryotic translation elongation factor 1 complex | IEP | Predicted GO |
BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
BP | GO:0006002 | fructose 6-phosphate metabolic process | IEP | Predicted GO |
BP | GO:0006082 | organic acid metabolic process | IEP | Predicted GO |
BP | GO:0006090 | pyruvate metabolic process | IEP | Predicted GO |
BP | GO:0006091 | generation of precursor metabolites and energy | IEP | Predicted GO |
BP | GO:0006096 | glycolytic process | IEP | Predicted GO |
BP | GO:0006139 | nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006163 | purine nucleotide metabolic process | IEP | Predicted GO |
BP | GO:0006164 | purine nucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0006165 | nucleoside diphosphate phosphorylation | IEP | Predicted GO |
BP | GO:0006166 | purine ribonucleoside salvage | IEP | Predicted GO |
BP | GO:0006351 | transcription, DNA-templated | IEP | Predicted GO |
BP | GO:0006366 | transcription by RNA polymerase II | IEP | Predicted GO |
BP | GO:0006396 | RNA processing | IEP | Predicted GO |
BP | GO:0006397 | mRNA processing | IEP | Predicted GO |
BP | GO:0006412 | translation | IEP | Predicted GO |
BP | GO:0006414 | translational elongation | IEP | Predicted GO |
BP | GO:0006418 | tRNA aminoacylation for protein translation | IEP | Predicted GO |
BP | GO:0006430 | lysyl-tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0006433 | prolyl-tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0006434 | seryl-tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0006518 | peptide metabolic process | IEP | Predicted GO |
BP | GO:0006520 | cellular amino acid metabolic process | IEP | Predicted GO |
BP | GO:0006528 | asparagine metabolic process | IEP | Predicted GO |
BP | GO:0006529 | asparagine biosynthetic process | IEP | Predicted GO |
BP | GO:0006725 | cellular aromatic compound metabolic process | IEP | Predicted GO |
BP | GO:0006732 | coenzyme metabolic process | IEP | Predicted GO |
BP | GO:0006733 | oxidoreduction coenzyme metabolic process | IEP | Predicted GO |
BP | GO:0006753 | nucleoside phosphate metabolic process | IEP | Predicted GO |
BP | GO:0006754 | ATP biosynthetic process | IEP | Predicted GO |
BP | GO:0006757 | ATP generation from ADP | IEP | Predicted GO |
BP | GO:0006793 | phosphorus metabolic process | IEP | Predicted GO |
BP | GO:0006796 | phosphate-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006807 | nitrogen compound metabolic process | IEP | Predicted GO |
MF | GO:0008187 | poly-pyrimidine tract binding | IEP | Predicted GO |
BP | GO:0008380 | RNA splicing | IEP | Predicted GO |
MF | GO:0008443 | phosphofructokinase activity | IEP | Predicted GO |
MF | GO:0008452 | RNA ligase activity | IEP | Predicted GO |
MF | GO:0008796 | bis(5'-nucleosyl)-tetraphosphatase activity | IEP | Predicted GO |
BP | GO:0009056 | catabolic process | IEP | Predicted GO |
BP | GO:0009058 | biosynthetic process | IEP | Predicted GO |
BP | GO:0009059 | macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0009066 | aspartate family amino acid metabolic process | IEP | Predicted GO |
BP | GO:0009067 | aspartate family amino acid biosynthetic process | IEP | Predicted GO |
BP | GO:0009108 | coenzyme biosynthetic process | IEP | Predicted GO |
BP | GO:0009117 | nucleotide metabolic process | IEP | Predicted GO |
BP | GO:0009132 | nucleoside diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009135 | purine nucleoside diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009141 | nucleoside triphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009142 | nucleoside triphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009144 | purine nucleoside triphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009145 | purine nucleoside triphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009150 | purine ribonucleotide metabolic process | IEP | Predicted GO |
BP | GO:0009152 | purine ribonucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0009165 | nucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0009166 | nucleotide catabolic process | IEP | Predicted GO |
BP | GO:0009179 | purine ribonucleoside diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009185 | ribonucleoside diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009199 | ribonucleoside triphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009201 | ribonucleoside triphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009205 | purine ribonucleoside triphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009259 | ribonucleotide metabolic process | IEP | Predicted GO |
BP | GO:0009260 | ribonucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0009891 | positive regulation of biosynthetic process | IEP | Predicted GO |
BP | GO:0010468 | regulation of gene expression | IEP | Predicted GO |
BP | GO:0010557 | positive regulation of macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0010628 | positive regulation of gene expression | IEP | Predicted GO |
CC | GO:0015934 | large ribosomal subunit | IEP | Predicted GO |
CC | GO:0015935 | small ribosomal subunit | IEP | Predicted GO |
BP | GO:0015959 | diadenosine polyphosphate metabolic process | IEP | Predicted GO |
BP | GO:0015960 | diadenosine polyphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0015965 | diadenosine tetraphosphate metabolic process | IEP | Predicted GO |
BP | GO:0015966 | diadenosine tetraphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0016052 | carbohydrate catabolic process | IEP | Predicted GO |
BP | GO:0016053 | organic acid biosynthetic process | IEP | Predicted GO |
BP | GO:0016070 | RNA metabolic process | IEP | Predicted GO |
BP | GO:0016071 | mRNA metabolic process | IEP | Predicted GO |
CC | GO:0016281 | eukaryotic translation initiation factor 4F complex | IEP | Predicted GO |
BP | GO:0016310 | phosphorylation | IEP | Predicted GO |
MF | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | IEP | Predicted GO |
MF | GO:0016772 | transferase activity, transferring phosphorus-containing groups | IEP | Predicted GO |
MF | GO:0016778 | diphosphotransferase activity | IEP | Predicted GO |
MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
MF | GO:0016874 | ligase activity | IEP | Predicted GO |
MF | GO:0016875 | ligase activity, forming carbon-oxygen bonds | IEP | Predicted GO |
BP | GO:0017144 | drug metabolic process | IEP | Predicted GO |
BP | GO:0018130 | heterocycle biosynthetic process | IEP | Predicted GO |
MF | GO:0019200 | carbohydrate kinase activity | IEP | Predicted GO |
BP | GO:0019222 | regulation of metabolic process | IEP | Predicted GO |
BP | GO:0019359 | nicotinamide nucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0019362 | pyridine nucleotide metabolic process | IEP | Predicted GO |
BP | GO:0019363 | pyridine nucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0019438 | aromatic compound biosynthetic process | IEP | Predicted GO |
BP | GO:0019439 | aromatic compound catabolic process | IEP | Predicted GO |
BP | GO:0019637 | organophosphate metabolic process | IEP | Predicted GO |
BP | GO:0019693 | ribose phosphate metabolic process | IEP | Predicted GO |
BP | GO:0019752 | carboxylic acid metabolic process | IEP | Predicted GO |
CC | GO:0022625 | cytosolic large ribosomal subunit | IEP | Predicted GO |
CC | GO:0022627 | cytosolic small ribosomal subunit | IEP | Predicted GO |
MF | GO:0030246 | carbohydrate binding | IEP | Predicted GO |
MF | GO:0030371 | translation repressor activity | IEP | Predicted GO |
CC | GO:0030532 | small nuclear ribonucleoprotein complex | IEP | Predicted GO |
MF | GO:0030621 | U4 snRNA binding | IEP | Predicted GO |
CC | GO:0030880 | RNA polymerase complex | IEP | Predicted GO |
BP | GO:0031323 | regulation of cellular metabolic process | IEP | Predicted GO |
BP | GO:0031325 | positive regulation of cellular metabolic process | IEP | Predicted GO |
BP | GO:0031328 | positive regulation of cellular biosynthetic process | IEP | Predicted GO |
CC | GO:0031982 | vesicle | IEP | Predicted GO |
BP | GO:0032774 | RNA biosynthetic process | IEP | Predicted GO |
BP | GO:0032784 | regulation of DNA-templated transcription, elongation | IEP | Predicted GO |
BP | GO:0032786 | positive regulation of DNA-templated transcription, elongation | IEP | Predicted GO |
BP | GO:0032787 | monocarboxylic acid metabolic process | IEP | Predicted GO |
BP | GO:0033500 | carbohydrate homeostasis | IEP | Predicted GO |
MF | GO:0033677 | DNA/RNA helicase activity | IEP | Predicted GO |
MF | GO:0033678 | 5'-3' DNA/RNA helicase activity | IEP | Predicted GO |
MF | GO:0033679 | 3'-5' DNA/RNA helicase activity | IEP | Predicted GO |
MF | GO:0034062 | 5'-3' RNA polymerase activity | IEP | Predicted GO |
BP | GO:0034404 | nucleobase-containing small molecule biosynthetic process | IEP | Predicted GO |
MF | GO:0034511 | U3 snoRNA binding | IEP | Predicted GO |
BP | GO:0034641 | cellular nitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:0034645 | cellular macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0034654 | nucleobase-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0034655 | nucleobase-containing compound catabolic process | IEP | Predicted GO |
BP | GO:0042221 | response to chemical | IEP | Predicted GO |
BP | GO:0042493 | response to drug | IEP | Predicted GO |
BP | GO:0042593 | glucose homeostasis | IEP | Predicted GO |
BP | GO:0042866 | pyruvate biosynthetic process | IEP | Predicted GO |
BP | GO:0043038 | amino acid activation | IEP | Predicted GO |
BP | GO:0043039 | tRNA aminoacylation | IEP | Predicted GO |
BP | GO:0043043 | peptide biosynthetic process | IEP | Predicted GO |
BP | GO:0043094 | cellular metabolic compound salvage | IEP | Predicted GO |
BP | GO:0043101 | purine-containing compound salvage | IEP | Predicted GO |
MF | GO:0043142 | single-stranded DNA-dependent ATPase activity | IEP | Predicted GO |
BP | GO:0043170 | macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0043174 | nucleoside salvage | IEP | Predicted GO |
CC | GO:0043228 | non-membrane-bounded organelle | IEP | Predicted GO |
CC | GO:0043232 | intracellular non-membrane-bounded organelle | IEP | Predicted GO |
BP | GO:0043436 | oxoacid metabolic process | IEP | Predicted GO |
BP | GO:0043484 | regulation of RNA splicing | IEP | Predicted GO |
BP | GO:0043603 | cellular amide metabolic process | IEP | Predicted GO |
BP | GO:0043604 | amide biosynthetic process | IEP | Predicted GO |
MF | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity | IEP | Predicted GO |
BP | GO:0044238 | primary metabolic process | IEP | Predicted GO |
BP | GO:0044248 | cellular catabolic process | IEP | Predicted GO |
BP | GO:0044249 | cellular biosynthetic process | IEP | Predicted GO |
BP | GO:0044260 | cellular macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0044270 | cellular nitrogen compound catabolic process | IEP | Predicted GO |
BP | GO:0044271 | cellular nitrogen compound biosynthetic process | IEP | Predicted GO |
BP | GO:0044281 | small molecule metabolic process | IEP | Predicted GO |
BP | GO:0044283 | small molecule biosynthetic process | IEP | Predicted GO |
CC | GO:0044391 | ribosomal subunit | IEP | Predicted GO |
CC | GO:0044422 | organelle part | IEP | Predicted GO |
CC | GO:0044428 | nuclear part | IEP | Predicted GO |
CC | GO:0044445 | cytosolic part | IEP | Predicted GO |
CC | GO:0044446 | intracellular organelle part | IEP | Predicted GO |
CC | GO:0044451 | nucleoplasm part | IEP | Predicted GO |
MF | GO:0045182 | translation regulator activity | IEP | Predicted GO |
BP | GO:0045893 | positive regulation of transcription, DNA-templated | IEP | Predicted GO |
BP | GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0046031 | ADP metabolic process | IEP | Predicted GO |
BP | GO:0046034 | ATP metabolic process | IEP | Predicted GO |
BP | GO:0046390 | ribose phosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0046394 | carboxylic acid biosynthetic process | IEP | Predicted GO |
BP | GO:0046434 | organophosphate catabolic process | IEP | Predicted GO |
BP | GO:0046483 | heterocycle metabolic process | IEP | Predicted GO |
BP | GO:0046496 | nicotinamide nucleotide metabolic process | IEP | Predicted GO |
BP | GO:0046700 | heterocycle catabolic process | IEP | Predicted GO |
BP | GO:0046939 | nucleotide phosphorylation | IEP | Predicted GO |
MF | GO:0047334 | diphosphate-fructose-6-phosphate 1-phosphotransferase activity | IEP | Predicted GO |
MF | GO:0048029 | monosaccharide binding | IEP | Predicted GO |
BP | GO:0051171 | regulation of nitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:0051173 | positive regulation of nitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:0051186 | cofactor metabolic process | IEP | Predicted GO |
BP | GO:0051188 | cofactor biosynthetic process | IEP | Predicted GO |
BP | GO:0051254 | positive regulation of RNA metabolic process | IEP | Predicted GO |
BP | GO:0051260 | protein homooligomerization | IEP | Predicted GO |
BP | GO:0051262 | protein tetramerization | IEP | Predicted GO |
BP | GO:0051289 | protein homotetramerization | IEP | Predicted GO |
CC | GO:0055029 | nuclear DNA-directed RNA polymerase complex | IEP | Predicted GO |
BP | GO:0055086 | nucleobase-containing small molecule metabolic process | IEP | Predicted GO |
BP | GO:0060255 | regulation of macromolecule metabolic process | IEP | Predicted GO |
CC | GO:0061695 | transferase complex, transferring phosphorus-containing groups | IEP | Predicted GO |
BP | GO:0065003 | protein-containing complex assembly | IEP | Predicted GO |
BP | GO:0071704 | organic substance metabolic process | IEP | Predicted GO |
BP | GO:0072330 | monocarboxylic acid biosynthetic process | IEP | Predicted GO |
BP | GO:0072521 | purine-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0072522 | purine-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0072524 | pyridine-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0072525 | pyridine-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0080090 | regulation of primary metabolic process | IEP | Predicted GO |
MF | GO:0090079 | translation regulator activity, nucleic acid binding | IEP | Predicted GO |
BP | GO:0090304 | nucleic acid metabolic process | IEP | Predicted GO |
BP | GO:0090407 | organophosphate biosynthetic process | IEP | Predicted GO |
CC | GO:0097525 | spliceosomal snRNP complex | IEP | Predicted GO |
BP | GO:0097659 | nucleic acid-templated transcription | IEP | Predicted GO |
MF | GO:0097747 | RNA polymerase activity | IEP | Predicted GO |
CC | GO:0120114 | Sm-like protein family complex | IEP | Predicted GO |
MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
MF | GO:0140101 | catalytic activity, acting on a tRNA | IEP | Predicted GO |
BP | GO:1901135 | carbohydrate derivative metabolic process | IEP | Predicted GO |
BP | GO:1901137 | carbohydrate derivative biosynthetic process | IEP | Predicted GO |
BP | GO:1901292 | nucleoside phosphate catabolic process | IEP | Predicted GO |
BP | GO:1901293 | nucleoside phosphate biosynthetic process | IEP | Predicted GO |
BP | GO:1901360 | organic cyclic compound metabolic process | IEP | Predicted GO |
BP | GO:1901361 | organic cyclic compound catabolic process | IEP | Predicted GO |
BP | GO:1901362 | organic cyclic compound biosynthetic process | IEP | Predicted GO |
BP | GO:1901564 | organonitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:1901566 | organonitrogen compound biosynthetic process | IEP | Predicted GO |
BP | GO:1901575 | organic substance catabolic process | IEP | Predicted GO |
BP | GO:1901576 | organic substance biosynthetic process | IEP | Predicted GO |
BP | GO:1902680 | positive regulation of RNA biosynthetic process | IEP | Predicted GO |
BP | GO:1903508 | positive regulation of nucleic acid-templated transcription | IEP | Predicted GO |
CC | GO:1903561 | extracellular vesicle | IEP | Predicted GO |
CC | GO:1990234 | transferase complex | IEP | Predicted GO |
CC | GO:1990904 | ribonucleoprotein complex | IEP | Predicted GO |