PF3D7_1411400 (PREX)

Aliases : PREX

Description : SSF53098: Ribonuclease H-like superfamily, SSF56672: No description available, SSF52540: P-loop containing nucleoside triphosphate hydrolase, SSF56731: No description available. Pfam domain(s): PF01612: 3'-5' exonuclease, PF00476: DNA polymerase family A, PF13481: AAA domain.

Gene families : OG_01_0001324 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001324_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1411400
Cluster	P. falciparum: Cluster_41

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1031100	PREX	SSF56731: 20-02-2019, SSF52540: P-loop containing...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan predictions
MF	GO:0003676	nucleic acid binding	IEA	PlasmoDB
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003678	DNA helicase activity	IDA	PlasmoDB
MF	GO:0003678	DNA helicase activity	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003887	DNA-directed DNA polymerase activity	IDA	PlasmoDB
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan predictions
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	PlasmoDB
MF	GO:0003896	DNA primase activity	IDA	PlasmoDB
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	None	Extended
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	PlasmoDB
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	Interproscan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	PlasmoDB
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan predictions
BP	GO:0006260	DNA replication	IEA	PlasmoDB
BP	GO:0006261	DNA-dependent DNA replication	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IDA	PlasmoDB
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan predictions
MF	GO:0008408	3'-5' exonuclease activity	IEA	PlasmoDB
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
MF	GO:0034062	5'-3' RNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0097747	RNA polymerase activity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000723	telomere maintenance	IEP	Predicted GO
CC	GO:0000781	chromosome, telomeric region	IEP	Predicted GO
MF	GO:0003721	telomerase RNA reverse transcriptase activity	IEP	Predicted GO
MF	GO:0003964	RNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0004435	phosphatidylinositol phospholipase C activity	IEP	Predicted GO
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Predicted GO
MF	GO:0004536	deoxyribonuclease activity	IEP	Predicted GO
MF	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEP	Predicted GO
MF	GO:0004565	beta-galactosidase activity	IEP	Predicted GO
MF	GO:0004620	phospholipase activity	IEP	Predicted GO
MF	GO:0004629	phospholipase C activity	IEP	Predicted GO
CC	GO:0005938	cell cortex	IEP	Predicted GO
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Predicted GO
BP	GO:0006278	RNA-dependent DNA biosynthetic process	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0006721	terpenoid metabolic process	IEP	Predicted GO
BP	GO:0006855	drug transmembrane transport	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0007004	telomere maintenance via telomerase	IEP	Predicted GO
BP	GO:0007154	cell communication	IEP	Predicted GO
MF	GO:0008081	phosphoric diester hydrolase activity	IEP	Predicted GO
MF	GO:0008134	transcription factor binding	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
CC	GO:0008622	epsilon DNA polymerase complex	IEP	Predicted GO
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Predicted GO
CC	GO:0009341	beta-galactosidase complex	IEP	Predicted GO
MF	GO:0009378	four-way junction helicase activity	IEP	Predicted GO
BP	GO:0009432	SOS response	IEP	Predicted GO
BP	GO:0009991	response to extracellular stimulus	IEP	Predicted GO
BP	GO:0010833	telomere maintenance via telomere lengthening	IEP	Predicted GO
MF	GO:0015238	drug transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	IEP	Predicted GO
BP	GO:0015893	drug transport	IEP	Predicted GO
MF	GO:0015925	galactosidase activity	IEP	Predicted GO
BP	GO:0015977	carbon fixation	IEP	Predicted GO
BP	GO:0016114	terpenoid biosynthetic process	IEP	Predicted GO
BP	GO:0016226	iron-sulfur cluster assembly	IEP	Predicted GO
MF	GO:0016298	lipase activity	IEP	Predicted GO
MF	GO:0016744	transferase activity, transferring aldehyde or ketonic groups	IEP	Predicted GO
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEP	Predicted GO
MF	GO:0016831	carboxy-lyase activity	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
MF	GO:0016984	ribulose-bisphosphate carboxylase activity	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0030246	carbohydrate binding	IEP	Predicted GO
BP	GO:0031163	metallo-sulfur cluster assembly	IEP	Predicted GO
BP	GO:0031668	cellular response to extracellular stimulus	IEP	Predicted GO
BP	GO:0032065	cortical protein anchoring	IEP	Predicted GO
BP	GO:0032200	telomere organization	IEP	Predicted GO
BP	GO:0032202	telomere assembly	IEP	Predicted GO
BP	GO:0032203	telomere formation via telomerase	IEP	Predicted GO
BP	GO:0032507	maintenance of protein location in cell	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
CC	GO:0042575	DNA polymerase complex	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
BP	GO:0045185	maintenance of protein location	IEP	Predicted GO
BP	GO:0051235	maintenance of location	IEP	Predicted GO
BP	GO:0051651	maintenance of location in cell	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0060249	anatomical structure homeostasis	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
BP	GO:0071496	cellular response to external stimulus	IEP	Predicted GO
BP	GO:0071897	DNA biosynthetic process	IEP	Predicted GO
CC	GO:0099568	cytoplasmic region	IEP	Predicted GO
CC	GO:1990229	iron-sulfur cluster assembly complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001098	DNA-dir_DNA_pol_A_palm_dom	1651	2013
IPR002562	3'-5'_exonuclease_dom	1447	1618

External Links

PlasmoDB	811693
PlasmoDB	PF14_0112

PF3D7_1411400 (PREX)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation