PF3D7_1412600 (DHS)

Aliases : DHS

Description : SSF52467: DHS-like NAD/FAD-binding domain superfamily. Pfam domain(s): PF01916: Deoxyhypusine synthase.

Gene families : OG_01_0001320 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001320_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1412600
Cluster	P. falciparum: Cluster_5

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine	IEA	Interproscan predictions
BP	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine	IEA	PlasmoDB
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	None	Extended
BP	GO:0018193	peptidyl-amino acid modification	None	Extended
BP	GO:0018205	peptidyl-lysine modification	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0034038	deoxyhypusine synthase activity	IDA	PlasmoDB
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0050983	obsolete deoxyhypusine biosynthetic process from spermidine	IDA	PlasmoDB
BP	GO:0051604	protein maturation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0004003	ATP-dependent DNA helicase activity	IEP	Predicted GO
MF	GO:0004177	aminopeptidase activity	IEP	Predicted GO
MF	GO:0004301	epoxide hydrolase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
CC	GO:0005669	transcription factor TFIID complex	IEP	Predicted GO
CC	GO:0005832	chaperonin-containing T-complex	IEP	Predicted GO
CC	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	IEP	Predicted GO
CC	GO:0005849	mRNA cleavage factor complex	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006261	DNA-dependent DNA replication	IEP	Predicted GO
BP	GO:0006352	DNA-templated transcription, initiation	IEP	Predicted GO
BP	GO:0006366	transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	IEP	Predicted GO
BP	GO:0006378	mRNA polyadenylation	IEP	Predicted GO
BP	GO:0006379	mRNA cleavage	IEP	Predicted GO
BP	GO:0006401	RNA catabolic process	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006605	protein targeting	IEP	Predicted GO
BP	GO:0006626	protein targeting to mitochondrion	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006839	mitochondrial transport	IEP	Predicted GO
BP	GO:0006986	response to unfolded protein	IEP	Predicted GO
MF	GO:0008026	ATP-dependent helicase activity	IEP	Predicted GO
MF	GO:0008238	exopeptidase activity	IEP	Predicted GO
MF	GO:0008320	protein transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016801	hydrolase activity, acting on ether bonds	IEP	Predicted GO
MF	GO:0016803	ether hydrolase activity	IEP	Predicted GO
MF	GO:0022884	macromolecule transmembrane transporter activity	IEP	Predicted GO
MF	GO:0030507	spectrin binding	IEP	Predicted GO
BP	GO:0031123	RNA 3'-end processing	IEP	Predicted GO
BP	GO:0031124	mRNA 3'-end processing	IEP	Predicted GO
BP	GO:0035966	response to topologically incorrect protein	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
MF	GO:0042887	amide transmembrane transporter activity	IEP	Predicted GO
BP	GO:0043631	RNA polyadenylation	IEP	Predicted GO
CC	GO:0044451	nucleoplasm part	IEP	Predicted GO
CC	GO:0044798	nuclear transcription factor complex	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Predicted GO
BP	GO:0070585	protein localization to mitochondrion	IEP	Predicted GO
BP	GO:0072655	establishment of protein localization to mitochondrion	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	IEP	Predicted GO
BP	GO:0090501	RNA phosphodiester bond hydrolysis	IEP	Predicted GO
CC	GO:0090575	RNA polymerase II transcription factor complex	IEP	Predicted GO
CC	GO:0101031	chaperone complex	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
MF	GO:1904680	peptide transmembrane transporter activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002773	Deoxyhypusine_synthase	303	482
IPR002773	Deoxyhypusine_synthase	64	248

External Links

PlasmoDB	811706
PlasmoDB	PF14_0125

PF3D7_1412600 (DHS)

Expression Profile

Co-expression Networks

Functional Annotation