PF3D7_1422500 (HRD1)

Aliases : HRD1

Description : SSF57850: No description available. Pfam domain(s): PF13639: Ring finger domain.

Gene families : OG_01_0001279 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001279_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1422500
Cluster	P. falciparum: Cluster_20

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004842	ubiquitin-protein transferase activity	IDA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005783	endoplasmic reticulum	IDA	PlasmoDB
CC	GO:0005789	endoplasmic reticulum membrane	IDA	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010033	response to organic substance	None	Extended
BP	GO:0010243	response to organonitrogen compound	None	Extended
BP	GO:0010498	proteasomal protein catabolic process	None	Extended
BP	GO:0010564	regulation of cell cycle process	ISS	PlasmoDB
CC	GO:0016020	membrane	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	ISS	PlasmoDB
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019787	ubiquitin-like protein transferase activity	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
BP	GO:0030163	protein catabolic process	None	Extended
BP	GO:0030433	ubiquitin-dependent ERAD pathway	ISS	PlasmoDB
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034976	response to endoplasmic reticulum stress	None	Extended
BP	GO:0036503	ERAD pathway	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044432	endoplasmic reticulum part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0051726	regulation of cell cycle	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901565	organonitrogen compound catabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
BP	GO:1901698	response to nitrogen compound	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
CC	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
BP	GO:0000338	protein deneddylation	IEP	Predicted GO
CC	GO:0000781	chromosome, telomeric region	IEP	Predicted GO
CC	GO:0000785	chromatin	IEP	Predicted GO
CC	GO:0000786	nucleosome	IEP	Predicted GO
CC	GO:0000791	euchromatin	IEP	Predicted GO
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Predicted GO
MF	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IEP	Predicted GO
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005798	Golgi-associated vesicle	IEP	Predicted GO
BP	GO:0006743	ubiquinone metabolic process	IEP	Predicted GO
BP	GO:0006744	ubiquinone biosynthetic process	IEP	Predicted GO
BP	GO:0006873	cellular ion homeostasis	IEP	Predicted GO
BP	GO:0006885	regulation of pH	IEP	Predicted GO
BP	GO:0006897	endocytosis	IEP	Predicted GO
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
BP	GO:0007035	vacuolar acidification	IEP	Predicted GO
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Predicted GO
CC	GO:0010494	cytoplasmic stress granule	IEP	Predicted GO
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
BP	GO:0016579	protein deubiquitination	IEP	Predicted GO
CC	GO:0016592	mediator complex	IEP	Predicted GO
BP	GO:0017148	negative regulation of translation	IEP	Predicted GO
BP	GO:0022406	membrane docking	IEP	Predicted GO
BP	GO:0030003	cellular cation homeostasis	IEP	Predicted GO
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	IEP	Predicted GO
CC	GO:0030133	transport vesicle	IEP	Predicted GO
CC	GO:0030135	coated vesicle	IEP	Predicted GO
CC	GO:0030136	clathrin-coated vesicle	IEP	Predicted GO
CC	GO:0030140	trans-Golgi network transport vesicle	IEP	Predicted GO
BP	GO:0030641	regulation of cellular pH	IEP	Predicted GO
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0032269	negative regulation of cellular protein metabolic process	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0032993	protein-DNA complex	IEP	Predicted GO
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Predicted GO
CC	GO:0033180	proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
BP	GO:0034249	negative regulation of cellular amide metabolic process	IEP	Predicted GO
CC	GO:0035770	ribonucleoprotein granule	IEP	Predicted GO
MF	GO:0036442	proton-exporting ATPase activity	IEP	Predicted GO
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEP	Predicted GO
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	IEP	Predicted GO
BP	GO:0042180	cellular ketone metabolic process	IEP	Predicted GO
BP	GO:0042181	ketone biosynthetic process	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0044437	vacuolar part	IEP	Predicted GO
CC	GO:0044815	DNA packaging complex	IEP	Predicted GO
BP	GO:0045851	pH reduction	IEP	Predicted GO
MF	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEP	Predicted GO
MF	GO:0046982	protein heterodimerization activity	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
BP	GO:0048278	vesicle docking	IEP	Predicted GO
BP	GO:0050801	ion homeostasis	IEP	Predicted GO
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051248	negative regulation of protein metabolic process	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0051452	intracellular pH reduction	IEP	Predicted GO
BP	GO:0051453	regulation of intracellular pH	IEP	Predicted GO
BP	GO:0051640	organelle localization	IEP	Predicted GO
BP	GO:0055067	monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0055080	cation homeostasis	IEP	Predicted GO
BP	GO:0055082	cellular chemical homeostasis	IEP	Predicted GO
MF	GO:0060089	molecular transducer activity	IEP	Predicted GO
BP	GO:0070646	protein modification by small protein removal	IEP	Predicted GO
MF	GO:0097472	cyclin-dependent protein kinase activity	IEP	Predicted GO
BP	GO:0098657	import into cell	IEP	Predicted GO
CC	GO:0098687	chromosomal region	IEP	Predicted GO
BP	GO:0098771	inorganic ion homeostasis	IEP	Predicted GO
MF	GO:0101005	ubiquitinyl hydrolase activity	IEP	Predicted GO
BP	GO:0140029	exocytic process	IEP	Predicted GO
BP	GO:0140056	organelle localization by membrane tethering	IEP	Predicted GO
BP	GO:1901661	quinone metabolic process	IEP	Predicted GO
BP	GO:1901663	quinone biosynthetic process	IEP	Predicted GO
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001841	Znf_RING	297	337

External Links

PlasmoDB	811797
PlasmoDB	PF14_0215

PF3D7_1422500 (HRD1)

Expression Profile

Co-expression Networks

Functional Annotation