PF3D7_1437200

Description : SSF48168: "Ribonucleotide reductase R1 subunit, N-terminal", SSF51998: No description available. Pfam domain(s): PF03477: ATP cone domain, PF00317: "Ribonucleotide reductase, all-alpha domain", PF02867: "Ribonucleotide reductase, barrel domain".

Gene families : OG_01_0000797 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000797_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1437200
Cluster	P. falciparum: Cluster_17

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEA	Interproscan predictions
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005971	ribonucleoside-diphosphate reductase complex	ISS	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	ISM	PlasmoDB
BP	GO:0006260	DNA replication	IEA	Interproscan predictions
BP	GO:0006260	DNA replication	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009262	deoxyribonucleotide metabolic process	None	Extended
BP	GO:0009263	deoxyribonucleotide biosynthetic process	ISS	PlasmoDB
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	None	Extended
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
CC	GO:0020011	apicoplast	RCA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044445	cytosolic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan predictions
BP	GO:0055114	oxidation-reduction process	IEA	PlasmoDB
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901137	carbohydrate derivative biosynthetic process	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990204	oxidoreductase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	IEP	Predicted GO
BP	GO:0000226	microtubule cytoskeleton organization	IEP	Predicted GO
CC	GO:0000808	origin recognition complex	IEP	Predicted GO
BP	GO:0002376	immune system process	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
BP	GO:0002682	regulation of immune system process	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003688	DNA replication origin binding	IEP	Predicted GO
MF	GO:0003690	double-stranded DNA binding	IEP	Predicted GO
MF	GO:0004402	histone acetyltransferase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Predicted GO
MF	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IEP	Predicted GO
MF	GO:0005507	copper ion binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Predicted GO
CC	GO:0005874	microtubule	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006825	copper ion transport	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
CC	GO:0008540	proteasome regulatory particle, base subcomplex	IEP	Predicted GO
BP	GO:0009894	regulation of catabolic process	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
BP	GO:0018105	peptidyl-serine phosphorylation	IEP	Predicted GO
BP	GO:0018209	peptidyl-serine modification	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
MF	GO:0030983	mismatched DNA binding	IEP	Predicted GO
MF	GO:0034212	peptide N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0042176	regulation of protein catabolic process	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
CC	GO:0043264	extracellular non-membrane-bounded organelle	IEP	Predicted GO
MF	GO:0043565	sequence-specific DNA binding	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:0050776	regulation of immune response	IEP	Predicted GO
BP	GO:0051259	protein complex oligomerization	IEP	Predicted GO
BP	GO:0051262	protein tetramerization	IEP	Predicted GO
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0070682	proteasome regulatory particle assembly	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
CC	GO:0085026	tubovesicular membrane network	IEP	Predicted GO
MF	GO:0097472	cyclin-dependent protein kinase activity	IEP	Predicted GO
CC	GO:0099080	supramolecular complex	IEP	Predicted GO
CC	GO:0099081	supramolecular polymer	IEP	Predicted GO
CC	GO:0099512	supramolecular fiber	IEP	Predicted GO
CC	GO:0099513	polymeric cytoskeletal fiber	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
MF	GO:1990837	sequence-specific double-stranded DNA binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR005144	ATP-cone_dom	42	129
IPR013509	RNR_lsu_N	181	251
IPR000788	RNR_lg_C	255	779

External Links

PlasmoDB	811934
PlasmoDB	PF14_0352

PF3D7_1437200

Expression Profile

Co-expression Networks

Functional Annotation