PF3D7_1439100

Description : SSF46785: Winged helix DNA-binding domain superfamily, SSF52540: P-loop containing nucleoside triphosphate hydrolase, SSF158702: No description available, SSF81296: Immunoglobulin E-set. Pfam domain(s): PF02889: Sec63 Brl domain, PF00270: DEAD/DEAH box helicase, PF00271: Helicase conserved C-terminal domain.

Gene families : OG_01_0000079 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000079_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1439100
Cluster	P. falciparum: Cluster_47

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0522900	BRR2	SSF158702: 20-02-2019, SSF52540: P-loop containing...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan predictions
MF	GO:0003676	nucleic acid binding	IEA	PlasmoDB
MF	GO:0003724	RNA helicase activity	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004004	ATP-dependent RNA helicase activity	ISS	PlasmoDB
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
MF	GO:0008026	ATP-dependent helicase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
MF	GO:0008186	RNA-dependent ATPase activity	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0070035	purine NTP-dependent helicase activity	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000922	spindle pole	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0003924	GTPase activity	IEP	Predicted GO
MF	GO:0004407	histone deacetylase activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005765	lysosomal membrane	IEP	Predicted GO
CC	GO:0005774	vacuolar membrane	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0007275	multicellular organism development	IEP	Predicted GO
BP	GO:0009790	embryo development	IEP	Predicted GO
BP	GO:0009913	epidermal cell differentiation	IEP	Predicted GO
CC	GO:0010008	endosome membrane	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
MF	GO:0016433	rRNA (adenine) methyltransferase activity	IEP	Predicted GO
MF	GO:0017136	NAD-dependent histone deacetylase activity	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0030154	cell differentiation	IEP	Predicted GO
BP	GO:0030216	keratinocyte differentiation	IEP	Predicted GO
MF	GO:0030743	rRNA (adenosine-2'-O-)-methyltransferase activity	IEP	Predicted GO
BP	GO:0030855	epithelial cell differentiation	IEP	Predicted GO
CC	GO:0031902	late endosome membrane	IEP	Predicted GO
CC	GO:0031910	cytostome	IEP	Predicted GO
BP	GO:0032501	multicellular organismal process	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0033558	protein deacetylase activity	IEP	Predicted GO
MF	GO:0034979	NAD-dependent protein deacetylase activity	IEP	Predicted GO
MF	GO:0043015	gamma-tubulin binding	IEP	Predicted GO
CC	GO:0044440	endosomal part	IEP	Predicted GO
BP	GO:0048856	anatomical structure development	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
MF	GO:0070403	NAD+ binding	IEP	Predicted GO
CC	GO:0098852	lytic vacuole membrane	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001650	Helicase_C	1784	1891
IPR001650	Helicase_C	712	832
IPR004179	Sec63-dom	953	1324
IPR004179	Sec63-dom	2144	2467
IPR011545	DEAD/DEAH_box_helicase_dom	343	634
IPR011545	DEAD/DEAH_box_helicase_dom	1373	1536

External Links

PlasmoDB	811952
PlasmoDB	PF14_0370

PF3D7_1439100

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation