PF3D7_1439900 (TIM)


Aliases : TIM

Description : SSF51351: Triosephosphate isomerase superfamily. Pfam domain(s): PF00121: Triosephosphate isomerase.


Gene families : OG_01_0001756 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001756_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_1439900
Cluster P. falciparum: Cluster_11

Target Alias Description ECC score Gene Family Method Actions
PBANKA_1303800 TIM SSF51351: Triosephosphate isomerase superfamily. Pfam... 0.06 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0004807 triose-phosphate isomerase activity IDA PlasmoDB
MF GO:0004807 triose-phosphate isomerase activity IEA Interproscan predictions
MF GO:0004807 triose-phosphate isomerase activity IEA PlasmoDB
BP GO:0006094 gluconeogenesis ISS PlasmoDB
BP GO:0006096 glycolytic process ISS PlasmoDB
BP GO:0006098 pentose-phosphate shunt ISS PlasmoDB
BP GO:0006633 fatty acid biosynthetic process ISS PlasmoDB
BP GO:0008152 metabolic process IEA PlasmoDB
Type GO Term Name Evidence Source
CC GO:0000015 phosphopyruvate hydratase complex IEP Predicted GO
MF GO:0000036 acyl carrier activity IEP Predicted GO
BP GO:0000045 autophagosome assembly IEP Predicted GO
MF GO:0000287 magnesium ion binding IEP Predicted GO
MF GO:0000295 adenine nucleotide transmembrane transporter activity IEP Predicted GO
BP GO:0002181 cytoplasmic translation IEP Predicted GO
CC GO:0002189 ribose phosphate diphosphokinase complex IEP Predicted GO
BP GO:0002253 activation of immune response IEP Predicted GO
BP GO:0002684 positive regulation of immune system process IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003725 double-stranded RNA binding IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEP Predicted GO
MF GO:0004017 adenylate kinase activity IEP Predicted GO
MF GO:0004364 glutathione transferase activity IEP Predicted GO
MF GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity IEP Predicted GO
MF GO:0004422 hypoxanthine phosphoribosyltransferase activity IEP Predicted GO
MF GO:0004448 isocitrate dehydrogenase activity IEP Predicted GO
MF GO:0004450 isocitrate dehydrogenase (NADP+) activity IEP Predicted GO
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0004634 phosphopyruvate hydratase activity IEP Predicted GO
MF GO:0004731 purine-nucleoside phosphorylase activity IEP Predicted GO
MF GO:0004743 pyruvate kinase activity IEP Predicted GO
MF GO:0004749 ribose phosphate diphosphokinase activity IEP Predicted GO
MF GO:0004784 superoxide dismutase activity IEP Predicted GO
MF GO:0005102 signaling receptor binding IEP Predicted GO
MF GO:0005125 cytokine activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005310 dicarboxylic acid transmembrane transporter activity IEP Predicted GO
MF GO:0005346 purine ribonucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0005347 ATP transmembrane transporter activity IEP Predicted GO
MF GO:0005471 ATP:ADP antiporter activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005527 macrolide binding IEP Predicted GO
MF GO:0005528 FK506 binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005746 mitochondrial respirasome IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005832 chaperonin-containing T-complex IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005853 eukaryotic translation elongation factor 1 complex IEP Predicted GO
CC GO:0005956 protein kinase CK2 complex IEP Predicted GO
BP GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process IEP Predicted GO
BP GO:0006102 isocitrate metabolic process IEP Predicted GO
BP GO:0006148 inosine catabolic process IEP Predicted GO
BP GO:0006152 purine nucleoside catabolic process IEP Predicted GO
BP GO:0006166 purine ribonucleoside salvage IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006449 regulation of translational termination IEP Predicted GO
BP GO:0006452 translational frameshifting IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006801 superoxide metabolic process IEP Predicted GO
BP GO:0006835 dicarboxylic acid transport IEP Predicted GO
BP GO:0006839 mitochondrial transport IEP Predicted GO
BP GO:0006863 purine nucleobase transport IEP Predicted GO
BP GO:0006950 response to stress IEP Predicted GO
BP GO:0006979 response to oxidative stress IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008379 thioredoxin peroxidase activity IEP Predicted GO
MF GO:0008509 anion transmembrane transporter activity IEP Predicted GO
MF GO:0008514 organic anion transmembrane transporter activity IEP Predicted GO
MF GO:0008696 4-amino-4-deoxychorismate lyase activity IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009119 ribonucleoside metabolic process IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
CC GO:0009986 cell surface IEP Predicted GO
BP GO:0010033 response to organic substance IEP Predicted GO
BP GO:0010243 response to organonitrogen compound IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010564 regulation of cell cycle process IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
MF GO:0015140 malate transmembrane transporter activity IEP Predicted GO
MF GO:0015215 nucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0015216 purine nucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0015217 ADP transmembrane transporter activity IEP Predicted GO
MF GO:0015291 secondary active transmembrane transporter activity IEP Predicted GO
MF GO:0015297 antiporter activity IEP Predicted GO
MF GO:0015301 anion:anion antiporter activity IEP Predicted GO
MF GO:0015367 oxoglutarate:malate antiporter activity IEP Predicted GO
MF GO:0015556 C4-dicarboxylate transmembrane transporter activity IEP Predicted GO
MF GO:0015605 organophosphate ester transmembrane transporter activity IEP Predicted GO
BP GO:0015740 C4-dicarboxylate transport IEP Predicted GO
BP GO:0015742 alpha-ketoglutarate transport IEP Predicted GO
BP GO:0015743 malate transport IEP Predicted GO
BP GO:0015851 nucleobase transport IEP Predicted GO
BP GO:0015858 nucleoside transport IEP Predicted GO
MF GO:0015932 nucleobase-containing compound transmembrane transporter activity IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0015935 small ribosomal subunit IEP Predicted GO
MF GO:0016209 antioxidant activity IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016833 oxo-acid-lyase activity IEP Predicted GO
MF GO:0016859 cis-trans isomerase activity IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0019153 protein-disulfide reductase (glutathione) activity IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
BP GO:0030433 ubiquitin-dependent ERAD pathway IEP Predicted GO
MF GO:0030545 receptor regulator activity IEP Predicted GO
CC GO:0031090 organelle membrane IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0031982 vesicle IEP Predicted GO
BP GO:0032238 adenosine transport IEP Predicted GO
BP GO:0032270 positive regulation of cellular protein metabolic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
MF GO:0033218 amide binding IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
BP GO:0034250 positive regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
BP GO:0034976 response to endoplasmic reticulum stress IEP Predicted GO
BP GO:0036503 ERAD pathway IEP Predicted GO
BP GO:0042026 protein refolding IEP Predicted GO
BP GO:0042221 response to chemical IEP Predicted GO
BP GO:0042262 DNA protection IEP Predicted GO
BP GO:0042278 purine nucleoside metabolic process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
BP GO:0043101 purine-containing compound salvage IEP Predicted GO
MF GO:0043139 5'-3' DNA helicase activity IEP Predicted GO
MF GO:0043141 ATP-dependent 5'-3' DNA helicase activity IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043174 nucleoside salvage IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043230 extracellular organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043243 positive regulation of protein complex disassembly IEP Predicted GO
BP GO:0043244 regulation of protein complex disassembly IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
MF GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044429 mitochondrial part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
MF GO:0044620 ACP phosphopantetheine attachment site binding IEP Predicted GO
BP GO:0045727 positive regulation of translation IEP Predicted GO
BP GO:0045901 positive regulation of translational elongation IEP Predicted GO
BP GO:0045905 positive regulation of translational termination IEP Predicted GO
BP GO:0046102 inosine metabolic process IEP Predicted GO
BP GO:0046128 purine ribonucleoside metabolic process IEP Predicted GO
BP GO:0046130 purine ribonucleoside catabolic process IEP Predicted GO
BP GO:0046391 5-phosphoribose 1-diphosphate metabolic process IEP Predicted GO
BP GO:0046777 protein autophosphorylation IEP Predicted GO
MF GO:0048018 receptor ligand activity IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048584 positive regulation of response to stimulus IEP Predicted GO
MF GO:0050661 NADP binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
BP GO:0050778 positive regulation of immune response IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051181 cofactor transport IEP Predicted GO
MF GO:0051192 prosthetic group binding IEP Predicted GO
BP GO:0051247 positive regulation of protein metabolic process IEP Predicted GO
BP GO:0051260 protein homooligomerization IEP Predicted GO
BP GO:0051262 protein tetramerization IEP Predicted GO
MF GO:0051287 NAD binding IEP Predicted GO
BP GO:0051289 protein homotetramerization IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
CC GO:0070469 respirasome IEP Predicted GO
BP GO:0072593 reactive oxygen species metabolic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0098772 molecular function regulator IEP Predicted GO
MF GO:0099516 ion antiporter activity IEP Predicted GO
CC GO:0101031 chaperone complex IEP Predicted GO
MF GO:0106130 purine phosphoribosyltransferase activity IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
MF GO:1901505 carbohydrate derivative transmembrane transporter activity IEP Predicted GO
BP GO:1901565 organonitrogen compound catabolic process IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
BP GO:1901698 response to nitrogen compound IEP Predicted GO
CC GO:1903561 extracellular vesicle IEP Predicted GO
BP GO:1905037 autophagosome organization IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR000652 Triosephosphate_isomerase 6 244
PlasmoDB 811960
PlasmoDB PF14_0378