PF3D7_1446400 (pdhB)

Aliases : pdhB

Description : SSF52922: Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II, SSF52518: Thiamin diphosphate-binding fold. Pfam domain(s): PF02779: "Transketolase, pyrimidine binding domain", PF02780: "Transketolase, C-terminal domain".

Gene families : OG_01_0003040 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0003040_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1446400
Cluster	P. falciparum: Cluster_1

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	PlasmoDB
MF	GO:0004738	pyruvate dehydrogenase activity	None	Extended
MF	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity	ISS	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006084	acetyl-CoA metabolic process	None	Extended
BP	GO:0006085	acetyl-CoA biosynthetic process	None	Extended
BP	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	IC	PlasmoDB
BP	GO:0006090	pyruvate metabolic process	None	Extended
BP	GO:0006099	tricarboxylic acid cycle	ISS	PlasmoDB
BP	GO:0006101	citrate metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006164	purine nucleotide biosynthetic process	None	Extended
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006631	fatty acid metabolic process	None	Extended
BP	GO:0006633	fatty acid biosynthetic process	TAS	PlasmoDB
BP	GO:0006637	acyl-CoA metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006732	coenzyme metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	IEA	PlasmoDB
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009108	coenzyme biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009152	purine ribonucleotide biosynthetic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009260	ribonucleotide biosynthetic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
CC	GO:0016020	membrane	ISS	PlasmoDB
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	None	Extended
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	None	Extended
BP	GO:0016999	antibiotic metabolic process	None	Extended
BP	GO:0017144	drug metabolic process	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
BP	GO:0032787	monocarboxylic acid metabolic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033865	nucleoside bisphosphate metabolic process	None	Extended
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	None	Extended
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	None	Extended
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	None	Extended
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	None	Extended
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0035383	thioester metabolic process	None	Extended
BP	GO:0035384	thioester biosynthetic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0043604	amide biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
CC	GO:0045254	pyruvate dehydrogenase complex	ISS	PlasmoDB
BP	GO:0046390	ribose phosphate biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0051188	cofactor biosynthetic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071616	acyl-CoA biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072330	monocarboxylic acid biosynthetic process	None	Extended
BP	GO:0072350	tricarboxylic acid metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0072522	purine-containing compound biosynthetic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901137	carbohydrate derivative biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990204	oxidoreductase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0002178	palmitoyltransferase complex	IEP	Predicted GO
CC	GO:0002179	homodimeric serine palmitoyltransferase complex	IEP	Predicted GO
MF	GO:0003747	translation release factor activity	IEP	Predicted GO
MF	GO:0003876	AMP deaminase activity	IEP	Predicted GO
MF	GO:0004045	aminoacyl-tRNA hydrolase activity	IEP	Predicted GO
MF	GO:0004312	fatty acid synthase activity	IEP	Predicted GO
MF	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity	IEP	Predicted GO
MF	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IEP	Predicted GO
MF	GO:0004354	glutamate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004758	serine C-palmitoyltransferase activity	IEP	Predicted GO
CC	GO:0005741	mitochondrial outer membrane	IEP	Predicted GO
BP	GO:0006195	purine nucleotide catabolic process	IEP	Predicted GO
BP	GO:0006196	AMP catabolic process	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006415	translational termination	IEP	Predicted GO
BP	GO:0006536	glutamate metabolic process	IEP	Predicted GO
BP	GO:0006537	glutamate biosynthetic process	IEP	Predicted GO
BP	GO:0006665	sphingolipid metabolic process	IEP	Predicted GO
MF	GO:0008079	translation termination factor activity	IEP	Predicted GO
MF	GO:0008173	RNA methyltransferase activity	IEP	Predicted GO
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009125	nucleoside monophosphate catabolic process	IEP	Predicted GO
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009128	purine nucleoside monophosphate catabolic process	IEP	Predicted GO
BP	GO:0009154	purine ribonucleotide catabolic process	IEP	Predicted GO
BP	GO:0009158	ribonucleoside monophosphate catabolic process	IEP	Predicted GO
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009169	purine ribonucleoside monophosphate catabolic process	IEP	Predicted GO
BP	GO:0009261	ribonucleotide catabolic process	IEP	Predicted GO
MF	GO:0015035	protein disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
MF	GO:0016149	translation release factor activity, codon specific	IEP	Predicted GO
MF	GO:0016408	C-acyltransferase activity	IEP	Predicted GO
MF	GO:0016417	S-acyltransferase activity	IEP	Predicted GO
MF	GO:0016419	S-malonyltransferase activity	IEP	Predicted GO
MF	GO:0016420	malonyltransferase activity	IEP	Predicted GO
MF	GO:0016454	C-palmitoyltransferase activity	IEP	Predicted GO
BP	GO:0016571	histone methylation	IEP	Predicted GO
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Predicted GO
MF	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016746	transferase activity, transferring acyl groups	IEP	Predicted GO
MF	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	IEP	Predicted GO
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Predicted GO
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Predicted GO
CC	GO:0017059	serine C-palmitoyltransferase complex	IEP	Predicted GO
BP	GO:0018022	peptidyl-lysine methylation	IEP	Predicted GO
MF	GO:0019239	deaminase activity	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
CC	GO:0019867	outer membrane	IEP	Predicted GO
BP	GO:0030148	sphingolipid biosynthetic process	IEP	Predicted GO
MF	GO:0030170	pyridoxal phosphate binding	IEP	Predicted GO
CC	GO:0031211	endoplasmic reticulum palmitoyltransferase complex	IEP	Predicted GO
CC	GO:0031968	organelle outer membrane	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
BP	GO:0034968	histone lysine methylation	IEP	Predicted GO
MF	GO:0035064	methylated histone binding	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
BP	GO:0042737	drug catabolic process	IEP	Predicted GO
BP	GO:0043624	cellular protein complex disassembly	IEP	Predicted GO
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0046033	AMP metabolic process	IEP	Predicted GO
MF	GO:0047623	adenosine-phosphate deaminase activity	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0051536	iron-sulfur cluster binding	IEP	Predicted GO
MF	GO:0051540	metal cluster binding	IEP	Predicted GO
MF	GO:0070279	vitamin B6 binding	IEP	Predicted GO
BP	GO:0072523	purine-containing compound catabolic process	IEP	Predicted GO
MF	GO:0140030	modification-dependent protein binding	IEP	Predicted GO
MF	GO:0140034	methylation-dependent protein binding	IEP	Predicted GO
BP	GO:1901136	carbohydrate derivative catabolic process	IEP	Predicted GO
CC	GO:1905961	protein-cysteine S-palmitoyltransferase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR005475	Transketolase-like_Pyr-bd	94	266
IPR033248	Transketolase_C	282	403

External Links

PlasmoDB	812023
PlasmoDB	PF14_0441

PF3D7_1446400 (pdhB)

Expression Profile

Co-expression Networks

Functional Annotation