PF3D7_1449400 (MUS81)

Aliases : MUS81

Description : SSF47802: DNA polymerase lambda lyase domain superfamily, SSF52980: Restriction endonuclease type II-like. Pfam domain(s): PF02732: ERCC4 domain.

Gene families : OG_01_0001787 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001787_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1449400
Cluster	P. falciparum: Cluster_10

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	IEA	Interproscan predictions
MF	GO:0004518	nuclease activity	IEA	PlasmoDB
MF	GO:0004519	endonuclease activity	None	Extended
MF	GO:0004520	endodeoxyribonuclease activity	ISS	PlasmoDB
MF	GO:0004536	deoxyribonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	ISS	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0004003	ATP-dependent DNA helicase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0005506	iron ion binding	IEP	Predicted GO
CC	GO:0005656	nuclear pre-replicative complex	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006271	DNA strand elongation involved in DNA replication	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0006721	terpenoid metabolic process	IEP	Predicted GO
BP	GO:0007154	cell communication	IEP	Predicted GO
MF	GO:0008134	transcription factor binding	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
MF	GO:0009378	four-way junction helicase activity	IEP	Predicted GO
BP	GO:0009432	SOS response	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0009991	response to extracellular stimulus	IEP	Predicted GO
CC	GO:0016035	zeta DNA polymerase complex	IEP	Predicted GO
BP	GO:0016114	terpenoid biosynthetic process	IEP	Predicted GO
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Predicted GO
CC	GO:0020011	apicoplast	IEP	Predicted GO
BP	GO:0022616	DNA strand elongation	IEP	Predicted GO
BP	GO:0031668	cellular response to extracellular stimulus	IEP	Predicted GO
CC	GO:0032993	protein-DNA complex	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
CC	GO:0036387	pre-replicative complex	IEP	Predicted GO
CC	GO:0042575	DNA polymerase complex	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
MF	GO:0046429	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	IEP	Predicted GO
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Predicted GO
MF	GO:0052592	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	IEP	Predicted GO
BP	GO:0071496	cellular response to external stimulus	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006166	ERCC4_domain	996	1127

External Links

PlasmoDB	812052
PlasmoDB	PF14_0470

PF3D7_1449400 (MUS81)

Expression Profile

Co-expression Networks

Functional Annotation