PF3D7_1450100 (SRP54)

Aliases : SRP54

Description : SSF47364: "SRP/SRP receptor, N-terminal", SSF47446: "Signal recognition particle, SRP54 subunit, M-domain superfamily", SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF02978: Signal peptide binding domain, PF02881: "SRP54-type protein, helical bundle domain", PF00448: "SRP54-type protein, GTPase domain".

Gene families : OG_01_0001791 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001791_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1450100
Cluster	P. falciparum: Cluster_35

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1313800	SRP54	SSF47446: Signal recognition particle, SRP54 subunit,...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0001882	nucleoside binding	None	Extended
MF	GO:0001883	purine nucleoside binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003924	GTPase activity	IEA	PlasmoDB
MF	GO:0005048	signal sequence binding	ISS	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	PlasmoDB
MF	GO:0005525	GTP binding	IEA	Interproscan predictions
MF	GO:0005525	GTP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IDA	PlasmoDB
CC	GO:0005786	signal recognition particle, endoplasmic reticulum targeting	RCA	PlasmoDB
CC	GO:0005789	endoplasmic reticulum membrane	IDA	PlasmoDB
CC	GO:0005829	cytosol	IDA	PlasmoDB
BP	GO:0006605	protein targeting	None	Extended
BP	GO:0006612	protein targeting to membrane	None	Extended
BP	GO:0006613	cotranslational protein targeting to membrane	None	Extended
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	RCA	PlasmoDB
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEA	Interproscan predictions
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEA	PlasmoDB
BP	GO:0006810	transport	None	Extended
BP	GO:0006886	intracellular protein transport	None	Extended
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008312	7S RNA binding	IDA	PlasmoDB
MF	GO:0008312	7S RNA binding	IEA	Interproscan predictions
MF	GO:0008312	7S RNA binding	IEA	PlasmoDB
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
CC	GO:0016020	membrane	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
MF	GO:0032549	ribonucleoside binding	None	Extended
MF	GO:0032550	purine ribonucleoside binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
MF	GO:0033218	amide binding	None	Extended
BP	GO:0033365	protein localization to organelle	None	Extended
BP	GO:0034613	cellular protein localization	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042277	peptide binding	None	Extended
BP	GO:0042886	amide transport	None	Extended
MF	GO:0043021	ribonucleoprotein complex binding	None	Extended
MF	GO:0043022	ribosome binding	RCA	PlasmoDB
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044432	endoplasmic reticulum part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0044877	protein-containing complex binding	None	Extended
BP	GO:0045047	protein targeting to ER	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
CC	GO:0048500	signal recognition particle	IEA	Interproscan predictions
CC	GO:0048500	signal recognition particle	IEA	PlasmoDB
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0070727	cellular macromolecule localization	None	Extended
BP	GO:0070972	protein localization to endoplasmic reticulum	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
BP	GO:0072594	establishment of protein localization to organelle	None	Extended
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	None	Extended
BP	GO:0072657	protein localization to membrane	None	Extended
BP	GO:0090150	establishment of protein localization to membrane	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1990904	ribonucleoprotein complex	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000323	lytic vacuole	IEP	Predicted GO
MF	GO:0004356	glutamate-ammonia ligase activity	IEP	Predicted GO
MF	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004725	protein tyrosine phosphatase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005381	iron ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005681	spliceosomal complex	IEP	Predicted GO
CC	GO:0005685	U1 snRNP	IEP	Predicted GO
CC	GO:0005764	lysosome	IEP	Predicted GO
CC	GO:0005767	secondary lysosome	IEP	Predicted GO
CC	GO:0005773	vacuole	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006334	nucleosome assembly	IEP	Predicted GO
BP	GO:0006498	N-terminal protein lipidation	IEP	Predicted GO
BP	GO:0006499	N-terminal protein myristoylation	IEP	Predicted GO
BP	GO:0006541	glutamine metabolic process	IEP	Predicted GO
BP	GO:0006542	glutamine biosynthetic process	IEP	Predicted GO
BP	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006820	anion transport	IEP	Predicted GO
BP	GO:0006855	drug transmembrane transport	IEP	Predicted GO
BP	GO:0006857	oligopeptide transport	IEP	Predicted GO
BP	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0008593	regulation of Notch signaling pathway	IEP	Predicted GO
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Predicted GO
MF	GO:0009678	hydrogen-translocating pyrophosphatase activity	IEP	Predicted GO
BP	GO:0009966	regulation of signal transduction	IEP	Predicted GO
BP	GO:0009967	positive regulation of signal transduction	IEP	Predicted GO
BP	GO:0010646	regulation of cell communication	IEP	Predicted GO
BP	GO:0010647	positive regulation of cell communication	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015091	ferric iron transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015093	ferrous iron transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015908	fatty acid transport	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
MF	GO:0016211	ammonia ligase activity	IEP	Predicted GO
MF	GO:0016746	transferase activity, transferring acyl groups	IEP	Predicted GO
MF	GO:0016880	acid-ammonia (or amide) ligase activity	IEP	Predicted GO
BP	GO:0018377	protein myristoylation	IEP	Predicted GO
MF	GO:0019107	myristoyltransferase activity	IEP	Predicted GO
CC	GO:0020005	symbiont-containing vacuole membrane	IEP	Predicted GO
CC	GO:0020020	food vacuole	IEP	Predicted GO
CC	GO:0020036	Maurer's cleft	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0023051	regulation of signaling	IEP	Predicted GO
BP	GO:0023056	positive regulation of signaling	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
CC	GO:0030139	endocytic vesicle	IEP	Predicted GO
MF	GO:0030515	snoRNA binding	IEP	Predicted GO
BP	GO:0031365	N-terminal protein amino acid modification	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0032010	phagolysosome	IEP	Predicted GO
CC	GO:0033643	host cell part	IEP	Predicted GO
CC	GO:0033646	host intracellular part	IEP	Predicted GO
CC	GO:0033655	host cell cytoplasm part	IEP	Predicted GO
BP	GO:0034635	glutathione transport	IEP	Predicted GO
BP	GO:0034728	nucleosome organization	IEP	Predicted GO
BP	GO:0042939	tripeptide transport	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
BP	GO:0043484	regulation of RNA splicing	IEP	Predicted GO
BP	GO:0043952	protein transport by the Sec complex	IEP	Predicted GO
CC	GO:0044164	host cell cytosol	IEP	Predicted GO
CC	GO:0044217	other organism part	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
CC	GO:0045335	phagocytic vesicle	IEP	Predicted GO
BP	GO:0045747	positive regulation of Notch signaling pathway	IEP	Predicted GO
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0046915	transition metal ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0048193	Golgi vesicle transport	IEP	Predicted GO
BP	GO:0048584	positive regulation of response to stimulus	IEP	Predicted GO
BP	GO:0050684	regulation of mRNA processing	IEP	Predicted GO
BP	GO:0051181	cofactor transport	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0072337	modified amino acid transport	IEP	Predicted GO
BP	GO:0072348	sulfur compound transport	IEP	Predicted GO
MF	GO:0072509	divalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0072510	trivalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
CC	GO:0097619	PTEX complex	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
BP	GO:1903311	regulation of mRNA metabolic process	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004125	Signal_recog_particle_SRP54_M	327	427
IPR013822	Signal_recog_particl_SRP54_hlx	6	83
IPR000897	SRP54_GTPase_dom	102	296

External Links

PlasmoDB	812059
PlasmoDB	PF14_0477

PF3D7_1450100 (SRP54)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation