PF3D7_1453500 (NNT)

Aliases : NNT

Description : SSF52283: No description available, SSF51735: NAD(P)-binding domain superfamily, SSF52467: DHS-like NAD/FAD-binding domain superfamily. Pfam domain(s): PF02233: NAD(P) transhydrogenase beta subunit, PF01262: "Alanine dehydrogenase/PNT, C-terminal domain", PF05222: "Alanine dehydrogenase/PNT, N-terminal domain", PF12769: "4TM region of pyridine nucleotide transhydrogenase, mitoch".

Gene families : OG_01_0001803 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001803_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1453500
Cluster	P. falciparum: Cluster_1

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1317200	NNT	SSF52467: DHS-like NAD/FAD-binding domain superfamily,...	0.15	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	ISS	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
CC	GO:0016021	integral component of membrane	ISM	PlasmoDB
MF	GO:0016491	oxidoreductase activity	IEA	PlasmoDB
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050661	NADP binding	ISS	PlasmoDB
MF	GO:0050662	coenzyme binding	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	PlasmoDB
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000150	recombinase activity	IEP	Predicted GO
BP	GO:0000270	peptidoglycan metabolic process	IEP	Predicted GO
BP	GO:0000271	polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Predicted GO
BP	GO:0000725	recombinational repair	IEP	Predicted GO
BP	GO:0000902	cell morphogenesis	IEP	Predicted GO
MF	GO:0003684	damaged DNA binding	IEP	Predicted GO
MF	GO:0003977	UDP-N-acetylglucosamine diphosphorylase activity	IEP	Predicted GO
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Predicted GO
MF	GO:0005044	scavenger receptor activity	IEP	Predicted GO
CC	GO:0005868	cytoplasmic dynein complex	IEP	Predicted GO
CC	GO:0005892	acetylcholine-gated channel complex	IEP	Predicted GO
BP	GO:0005976	polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0006004	fucose metabolic process	IEP	Predicted GO
BP	GO:0006022	aminoglycan metabolic process	IEP	Predicted GO
BP	GO:0006023	aminoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0006024	glycosaminoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0006166	purine ribonucleoside salvage	IEP	Predicted GO
BP	GO:0006190	inosine salvage	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006310	DNA recombination	IEP	Predicted GO
MF	GO:0008239	dipeptidyl-peptidase activity	IEP	Predicted GO
MF	GO:0008252	nucleotidase activity	IEP	Predicted GO
MF	GO:0008253	5'-nucleotidase activity	IEP	Predicted GO
BP	GO:0008360	regulation of cell shape	IEP	Predicted GO
MF	GO:0008446	GDP-mannose 4,6-dehydratase activity	IEP	Predicted GO
BP	GO:0008653	lipopolysaccharide metabolic process	IEP	Predicted GO
BP	GO:0009103	lipopolysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0009252	peptidoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0009653	anatomical structure morphogenesis	IEP	Predicted GO
MF	GO:0019134	glucosamine-1-phosphate N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0019236	response to pheromone	IEP	Predicted GO
BP	GO:0019673	GDP-mannose metabolic process	IEP	Predicted GO
CC	GO:0020025	subpellicular microtubule	IEP	Predicted GO
CC	GO:0020039	pellicle	IEP	Predicted GO
BP	GO:0022603	regulation of anatomical structure morphogenesis	IEP	Predicted GO
BP	GO:0022604	regulation of cell morphogenesis	IEP	Predicted GO
BP	GO:0030203	glycosaminoglycan metabolic process	IEP	Predicted GO
MF	GO:0030942	endoplasmic reticulum signal peptide binding	IEP	Predicted GO
BP	GO:0031297	replication fork processing	IEP	Predicted GO
BP	GO:0032989	cellular component morphogenesis	IEP	Predicted GO
BP	GO:0033692	cellular polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
CC	GO:0034702	ion channel complex	IEP	Predicted GO
MF	GO:0038024	cargo receptor activity	IEP	Predicted GO
MF	GO:0042800	histone methyltransferase activity (H3-K4 specific)	IEP	Predicted GO
BP	GO:0043101	purine-containing compound salvage	IEP	Predicted GO
BP	GO:0043174	nucleoside salvage	IEP	Predicted GO
CC	GO:0043235	receptor complex	IEP	Predicted GO
BP	GO:0044036	cell wall macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044038	cell wall macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Predicted GO
CC	GO:0044310	osmiophilic body	IEP	Predicted GO
CC	GO:0044312	crystalloid	IEP	Predicted GO
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
BP	GO:0046102	inosine metabolic process	IEP	Predicted GO
BP	GO:0046103	inosine biosynthetic process	IEP	Predicted GO
MF	GO:0046974	histone methyltransferase activity (H3-K9 specific)	IEP	Predicted GO
MF	GO:0050483	IMP 5'-nucleotidase activity	IEP	Predicted GO
BP	GO:0051567	histone H3-K9 methylation	IEP	Predicted GO
BP	GO:0051568	histone H3-K4 methylation	IEP	Predicted GO
BP	GO:0061647	histone H3-K9 modification	IEP	Predicted GO
MF	GO:0070001	aspartic-type peptidase activity	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
MF	GO:0070569	uridylyltransferase activity	IEP	Predicted GO
BP	GO:0070589	cellular component macromolecule biosynthetic process	IEP	Predicted GO
CC	GO:0071944	cell periphery	IEP	Predicted GO
CC	GO:0098797	plasma membrane protein complex	IEP	Predicted GO
CC	GO:0098802	plasma membrane receptor complex	IEP	Predicted GO
BP	GO:0120009	intermembrane lipid transfer	IEP	Predicted GO
MF	GO:0120013	intermembrane lipid transfer activity	IEP	Predicted GO
BP	GO:1902298	cell cycle DNA replication maintenance of fidelity	IEP	Predicted GO
CC	GO:1902495	transmembrane transporter complex	IEP	Predicted GO
CC	GO:1990351	transporter complex	IEP	Predicted GO
BP	GO:1990426	mitotic recombination-dependent replication fork processing	IEP	Predicted GO
BP	GO:1990505	mitotic DNA replication maintenance of fidelity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR007886	AlaDH/PNT_N	655	780
IPR034300	PNTB-like	97	556
IPR024605	NADP_transhyd_a_C	1093	1174
IPR007698	AlaDH/PNT_NAD(H)-bd	785	1016

External Links

PlasmoDB	812090
PlasmoDB	PF14_0508

PF3D7_1453500 (NNT)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation