PF3D7_1459000 (DBP5)

Aliases : DBP5

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF00270: DEAD/DEAH box helicase, PF00271: Helicase conserved C-terminal domain.

Gene families : OG_01_0001821 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001821_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1459000
Cluster	P. falciparum: Cluster_34

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1322700	DBP5	SSF52540: P-loop containing nucleoside triphosphate...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan predictions
MF	GO:0003676	nucleic acid binding	IEA	PlasmoDB
MF	GO:0003723	RNA binding	IDA	PlasmoDB
MF	GO:0003724	RNA helicase activity	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004004	ATP-dependent RNA helicase activity	IDA	PlasmoDB
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	TAS	PlasmoDB
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008026	ATP-dependent helicase activity	None	Extended
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008186	RNA-dependent ATPase activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IDA	PlasmoDB
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
BP	GO:0032392	DNA geometric change	None	Extended
BP	GO:0032508	DNA duplex unwinding	IDA	PlasmoDB
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0033677	DNA/RNA helicase activity	None	Extended
MF	GO:0033678	5'-3' DNA/RNA helicase activity	IDA	PlasmoDB
MF	GO:0033679	3'-5' DNA/RNA helicase activity	IDA	PlasmoDB
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043142	single-stranded DNA-dependent ATPase activity	IDA	PlasmoDB
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
MF	GO:0070035	purine NTP-dependent helicase activity	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000323	lytic vacuole	IEP	Predicted GO
BP	GO:0000350	generation of catalytic spliceosome for second transesterification step	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0001906	cell killing	IEP	Predicted GO
MF	GO:0003725	double-stranded RNA binding	IEP	Predicted GO
MF	GO:0003727	single-stranded RNA binding	IEP	Predicted GO
MF	GO:0003743	translation initiation factor activity	IEP	Predicted GO
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004806	triglyceride lipase activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005665	RNA polymerase II, core complex	IEP	Predicted GO
CC	GO:0005681	spliceosomal complex	IEP	Predicted GO
CC	GO:0005764	lysosome	IEP	Predicted GO
CC	GO:0005767	secondary lysosome	IEP	Predicted GO
CC	GO:0005773	vacuole	IEP	Predicted GO
CC	GO:0005850	eukaryotic translation initiation factor 2 complex	IEP	Predicted GO
BP	GO:0006334	nucleosome assembly	IEP	Predicted GO
BP	GO:0006366	transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006413	translational initiation	IEP	Predicted GO
BP	GO:0006417	regulation of translation	IEP	Predicted GO
BP	GO:0006446	regulation of translational initiation	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008187	poly-pyrimidine tract binding	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
BP	GO:0010468	regulation of gene expression	IEP	Predicted GO
BP	GO:0010608	posttranscriptional regulation of gene expression	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0019222	regulation of metabolic process	IEP	Predicted GO
BP	GO:0019835	cytolysis	IEP	Predicted GO
CC	GO:0020020	food vacuole	IEP	Predicted GO
CC	GO:0030139	endocytic vesicle	IEP	Predicted GO
CC	GO:0030430	host cell cytoplasm	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
BP	GO:0031323	regulation of cellular metabolic process	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
BP	GO:0031640	killing of cells of other organism	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0032010	phagolysosome	IEP	Predicted GO
BP	GO:0032268	regulation of cellular protein metabolic process	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0034248	regulation of cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043484	regulation of RNA splicing	IEP	Predicted GO
BP	GO:0044179	hemolysis in other organism	IEP	Predicted GO
BP	GO:0044364	disruption of cells of other organism	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044451	nucleoplasm part	IEP	Predicted GO
BP	GO:0044764	multi-organism cellular process	IEP	Predicted GO
CC	GO:0045335	phagocytic vesicle	IEP	Predicted GO
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0050684	regulation of mRNA processing	IEP	Predicted GO
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051246	regulation of protein metabolic process	IEP	Predicted GO
BP	GO:0051715	cytolysis in other organism	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0070001	aspartic-type peptidase activity	IEP	Predicted GO
BP	GO:0080090	regulation of primary metabolic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO
BP	GO:1903311	regulation of mRNA metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR011545	DEAD/DEAH_box_helicase_dom	350	513
IPR001650	Helicase_C	556	694

External Links

PlasmoDB	812145
PlasmoDB	PF14_0563

PF3D7_1459000 (DBP5)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation