PF3D7_1460400 (UCHL3)

Aliases : UCHL3

Description : SSF54001: Papain-like cysteine peptidase superfamily. Pfam domain(s): PF01088: "Ubiquitin carboxyl-terminal hydrolase, family 1".

Gene families : OG_01_0003080 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0003080_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1460400
Cluster	P. falciparum: Cluster_30

Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IDA	PlasmoDB
BP	GO:0000338	protein deneddylation	IDA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004221	obsolete ubiquitin thiolesterase activity	ISS	PlasmoDB
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEA	Interproscan predictions
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005622	intracellular	IEA	Interproscan predictions
CC	GO:0005622	intracellular	IEA	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	ISS	PlasmoDB
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	Interproscan predictions
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016579	protein deubiquitination	IDA	PlasmoDB
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019783	ubiquitin-like protein-specific protease activity	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
MF	GO:0032182	ubiquitin-like protein binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	None	Extended
MF	GO:0043130	ubiquitin binding	IDA	PlasmoDB
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0070646	protein modification by small protein removal	None	Extended
BP	GO:0070647	protein modification by small protein conjugation or removal	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0101005	ubiquitinyl hydrolase activity	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
MF	GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity	IEP	Predicted GO
MF	GO:0004311	farnesyltranstransferase activity	IEP	Predicted GO
MF	GO:0004337	geranyltranstransferase activity	IEP	Predicted GO
MF	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	IEP	Predicted GO
MF	GO:0004659	prenyltransferase activity	IEP	Predicted GO
CC	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	IEP	Predicted GO
CC	GO:0005849	mRNA cleavage factor complex	IEP	Predicted GO
BP	GO:0006103	2-oxoglutarate metabolic process	IEP	Predicted GO
BP	GO:0006378	mRNA polyadenylation	IEP	Predicted GO
BP	GO:0006379	mRNA cleavage	IEP	Predicted GO
BP	GO:0006405	RNA export from nucleus	IEP	Predicted GO
BP	GO:0006486	protein glycosylation	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0006873	cellular ion homeostasis	IEP	Predicted GO
BP	GO:0006885	regulation of pH	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
BP	GO:0007035	vacuolar acidification	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
MF	GO:0016409	palmitoyltransferase activity	IEP	Predicted GO
MF	GO:0016417	S-acyltransferase activity	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016746	transferase activity, transferring acyl groups	IEP	Predicted GO
MF	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	IEP	Predicted GO
MF	GO:0016748	succinyltransferase activity	IEP	Predicted GO
MF	GO:0016751	S-succinyltransferase activity	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0018345	protein palmitoylation	IEP	Predicted GO
MF	GO:0019843	rRNA binding	IEP	Predicted GO
BP	GO:0030003	cellular cation homeostasis	IEP	Predicted GO
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0030641	regulation of cellular pH	IEP	Predicted GO
BP	GO:0031123	RNA 3'-end processing	IEP	Predicted GO
BP	GO:0031124	mRNA 3'-end processing	IEP	Predicted GO
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Predicted GO
CC	GO:0033180	proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
BP	GO:0035690	cellular response to drug	IEP	Predicted GO
MF	GO:0036442	proton-exporting ATPase activity	IEP	Predicted GO
BP	GO:0043413	macromolecule glycosylation	IEP	Predicted GO
BP	GO:0043631	RNA polyadenylation	IEP	Predicted GO
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Predicted GO
MF	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	IEP	Predicted GO
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0045240	dihydrolipoyl dehydrogenase complex	IEP	Predicted GO
CC	GO:0045252	oxoglutarate dehydrogenase complex	IEP	Predicted GO
BP	GO:0045851	pH reduction	IEP	Predicted GO
MF	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
BP	GO:0050657	nucleic acid transport	IEP	Predicted GO
BP	GO:0050658	RNA transport	IEP	Predicted GO
BP	GO:0050801	ion homeostasis	IEP	Predicted GO
BP	GO:0051168	nuclear export	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051236	establishment of RNA localization	IEP	Predicted GO
BP	GO:0051302	regulation of cell division	IEP	Predicted GO
BP	GO:0051452	intracellular pH reduction	IEP	Predicted GO
BP	GO:0051453	regulation of intracellular pH	IEP	Predicted GO
BP	GO:0055067	monovalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0055080	cation homeostasis	IEP	Predicted GO
BP	GO:0055082	cellular chemical homeostasis	IEP	Predicted GO
BP	GO:0070085	glycosylation	IEP	Predicted GO
BP	GO:0070887	cellular response to chemical stimulus	IEP	Predicted GO
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	IEP	Predicted GO
BP	GO:0090501	RNA phosphodiester bond hydrolysis	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
BP	GO:0098771	inorganic ion homeostasis	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001578	Peptidase_C12_UCH	7	207

External Links

PlasmoDB	812158
PlasmoDB	PF14_0576

PF3D7_1460400 (UCHL3)

Expression Profile

Co-expression Networks

Functional Annotation