PF3D7_1462300

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF02263: "Guanylate-binding protein, N-terminal domain".

Gene families : OG_01_0001836 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001836_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1462300
Cluster	P. falciparum: Cluster_36

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1326000	No alias	SSF52540: P-loop containing nucleoside triphosphate...	0.05	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0001882	nucleoside binding	None	Extended
MF	GO:0001883	purine nucleoside binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003924	GTPase activity	IEA	Interproscan predictions
MF	GO:0003924	GTPase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	IEA	Interproscan predictions
MF	GO:0005525	GTP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032549	ribonucleoside binding	None	Extended
MF	GO:0032550	purine ribonucleoside binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0044425	membrane part	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000054	ribosomal subunit export from nucleus	IEP	Predicted GO
BP	GO:0000055	ribosomal large subunit export from nucleus	IEP	Predicted GO
CC	GO:0000177	cytoplasmic exosome (RNase complex)	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003713	transcription coactivator activity	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003724	RNA helicase activity	IEP	Predicted GO
MF	GO:0003743	translation initiation factor activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0004476	mannose-6-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0004527	exonuclease activity	IEP	Predicted GO
MF	GO:0004534	5'-3' exoribonuclease activity	IEP	Predicted GO
MF	GO:0004686	elongation factor-2 kinase activity	IEP	Predicted GO
MF	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005643	nuclear pore	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006360	transcription by RNA polymerase I	IEP	Predicted GO
BP	GO:0006413	translational initiation	IEP	Predicted GO
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006606	protein import into nucleus	IEP	Predicted GO
BP	GO:0006607	NLS-bearing protein import into nucleus	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
MF	GO:0008026	ATP-dependent helicase activity	IEP	Predicted GO
MF	GO:0008270	zinc ion binding	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009889	regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0010468	regulation of gene expression	IEP	Predicted GO
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0016049	cell growth	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016579	protein deubiquitination	IEP	Predicted GO
BP	GO:0017038	protein import	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
MF	GO:0019783	ubiquitin-like protein-specific protease activity	IEP	Predicted GO
MF	GO:0019899	enzyme binding	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0030014	CCR4-NOT complex	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
BP	GO:0031323	regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0031503	protein-containing complex localization	IEP	Predicted GO
MF	GO:0031625	ubiquitin protein ligase binding	IEP	Predicted GO
BP	GO:0032012	regulation of ARF protein signal transduction	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
BP	GO:0033750	ribosome localization	IEP	Predicted GO
BP	GO:0034504	protein localization to nucleus	IEP	Predicted GO
BP	GO:0035690	cellular response to drug	IEP	Predicted GO
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEP	Predicted GO
BP	GO:0040007	growth	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
MF	GO:0044389	ubiquitin-like protein ligase binding	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044613	nuclear pore central transport channel	IEP	Predicted GO
BP	GO:0046578	regulation of Ras protein signal transduction	IEP	Predicted GO
MF	GO:0046872	metal ion binding	IEP	Predicted GO
MF	GO:0046914	transition metal ion binding	IEP	Predicted GO
MF	GO:0051020	GTPase binding	IEP	Predicted GO
BP	GO:0051056	regulation of small GTPase mediated signal transduction	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051170	import into nucleus	IEP	Predicted GO
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051656	establishment of organelle localization	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Predicted GO
BP	GO:0070646	protein modification by small protein removal	IEP	Predicted GO
BP	GO:0070887	cellular response to chemical stimulus	IEP	Predicted GO
BP	GO:0071426	ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0080090	regulation of primary metabolic process	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
MF	GO:0101005	ubiquitinyl hydrolase activity	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1902531	regulation of intracellular signal transduction	IEP	Predicted GO
BP	GO:1902626	assembly of large subunit precursor of preribosome	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR015894	Guanylate-bd_N	138	216
IPR015894	Guanylate-bd_N	274	400

External Links

PlasmoDB	812175
PlasmoDB	PF14_0593

PF3D7_1462300

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation