PF3D7_API02900 (TUFA)

Aliases : TUFA

Description : SSF50447: "Translation protein, beta-barrel domain superfamily", SSF50465: "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal", SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF03144: Elongation factor Tu domain 2, PF00009: Elongation factor Tu GTP binding domain, PF03143: Elongation factor Tu C-terminal domain.

Gene families : OG_01_0000129 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000129_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_API02900
Cluster	P. falciparum: Cluster_29

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_API00280	TUFA	SSF50447: Translation protein, beta-barrel domain...	0.02	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0001882	nucleoside binding	None	Extended
MF	GO:0001883	purine nucleoside binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003924	GTPase activity	IEA	Interproscan predictions
MF	GO:0003924	GTPase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	IEA	Interproscan predictions
MF	GO:0005525	GTP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0009536	plastid	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
MF	GO:0032549	ribonucleoside binding	None	Extended
MF	GO:0032550	purine ribonucleoside binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004383	guanylate cyclase activity	IEP	Predicted GO
CC	GO:0005887	integral component of plasma membrane	IEP	Predicted GO
BP	GO:0006182	cGMP biosynthetic process	IEP	Predicted GO
BP	GO:0009187	cyclic nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009190	cyclic nucleotide biosynthetic process	IEP	Predicted GO
MF	GO:0009975	cyclase activity	IEP	Predicted GO
MF	GO:0015002	heme-copper terminal oxidase activity	IEP	Predicted GO
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Predicted GO
BP	GO:0035556	intracellular signal transduction	IEP	Predicted GO
BP	GO:0046068	cGMP metabolic process	IEP	Predicted GO
BP	GO:0052652	cyclic purine nucleotide metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004161	EFTu-like_2	235	305
IPR000795	TF_GTP-bd_dom	10	202
IPR004160	Transl_elong_EFTu/EF1A_C	312	408

External Links

PlasmoDB	PFC10_API0028

PF3D7_API02900 (TUFA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation