PBANKA_0710100 (KDH)

Aliases : KDH

Description : SSF52518: Thiamin diphosphate-binding fold. Pfam domain(s): PF16870: 2-oxoglutarate dehydrogenase C-terminal, PF02779: Transketolase, pyrimidine binding domain, PF16078: 2-oxoglutarate dehydrogenase N-terminus, PF00676: Dehydrogenase E1 component.

Gene families : OG_01_0000890 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000890_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_0710100
Cluster	P. berghei: Cluster_34

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006099	tricarboxylic acid cycle	IEA	PlasmoDB
BP	GO:0006101	citrate metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	IEA	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEA	Interproscan predictions
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEA	PlasmoDB
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	None	Extended
BP	GO:0016999	antibiotic metabolic process	None	Extended
BP	GO:0017144	drug metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0019842	vitamin binding	None	Extended
MF	GO:0030976	thiamine pyrophosphate binding	IEA	PlasmoDB
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	PlasmoDB
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072350	tricarboxylic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
MF	GO:1901681	sulfur compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0000723	telomere maintenance	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
MF	GO:0008026	ATP-dependent helicase activity	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
MF	GO:0008483	transaminase activity	IEP	Predicted GO
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Predicted GO
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016769	transferase activity, transferring nitrogenous groups	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
BP	GO:0032200	telomere organization	IEP	Predicted GO
BP	GO:0032392	DNA geometric change	IEP	Predicted GO
BP	GO:0032508	DNA duplex unwinding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Predicted GO
MF	GO:0043139	5'-3' DNA helicase activity	IEP	Predicted GO
MF	GO:0043142	single-stranded DNA-dependent ATPase activity	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Predicted GO
MF	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	IEP	Predicted GO
BP	GO:0060249	anatomical structure homeostasis	IEP	Predicted GO
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Predicted GO
MF	GO:0070548	L-glutamine aminotransferase activity	IEP	Predicted GO
MF	GO:0070567	cytidylyltransferase activity	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR031717	KGD_C	867	1021
IPR001017	DH_E1	263	577
IPR005475	Transketolase-like_Pyr-bd	649	860
IPR032106	2-oxogl_dehyd_N	41	72

External Links

PlasmoDB	PB001367.02.0
PlasmoDB	PB300676.00.0
PlasmoDB	PBANKA_071010

PBANKA_0710100 (KDH)

Expression Profile

Co-expression Networks

Functional Annotation