PBANKA_0804300 (MSH2-2)

Aliases : MSH2-2

Description : SSF48334: DNA mismatch repair protein MutS, core domain superfamily, SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF00488: MutS domain V, PF05188: MutS domain II, PF05192: MutS domain III.

Gene families : OG_01_0000121 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000121_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_0804300
Cluster	P. berghei: Cluster_6

Target	Alias	Description	ECC score	Gene Family Method	Actions
PF3D7_0706700	MSH2-2	SSF48334: "DNA mismatch repair protein MutS, core domain...	0.01	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan predictions
BP	GO:0006298	mismatch repair	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan predictions
MF	GO:0030983	mismatched DNA binding	IEA	PlasmoDB
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000255	allantoin metabolic process	IEP	Predicted GO
BP	GO:0000256	allantoin catabolic process	IEP	Predicted GO
BP	GO:0000350	generation of catalytic spliceosome for second transesterification step	IEP	Predicted GO
BP	GO:0000389	mRNA 3'-splice site recognition	IEP	Predicted GO
BP	GO:0000910	cytokinesis	IEP	Predicted GO
MF	GO:0003714	transcription corepressor activity	IEP	Predicted GO
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0003909	DNA ligase activity	IEP	Predicted GO
MF	GO:0003910	DNA ligase (ATP) activity	IEP	Predicted GO
MF	GO:0004037	allantoicase activity	IEP	Predicted GO
MF	GO:0004523	RNA-DNA hybrid ribonuclease activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005658	alpha DNA polymerase:primase complex	IEP	Predicted GO
CC	GO:0005875	microtubule associated complex	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006266	DNA ligation	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006813	potassium ion transport	IEP	Predicted GO
BP	GO:0007017	microtubule-based process	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
BP	GO:0022402	cell cycle process	IEP	Predicted GO
MF	GO:0022829	wide pore channel activity	IEP	Predicted GO
CC	GO:0030286	dynein complex	IEP	Predicted GO
CC	GO:0032299	ribonuclease H2 complex	IEP	Predicted GO
CC	GO:0032838	plasma membrane bounded cell projection cytoplasm	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
BP	GO:0036388	pre-replicative complex assembly	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
CC	GO:0042575	DNA polymerase complex	IEP	Predicted GO
BP	GO:0042737	drug catabolic process	IEP	Predicted GO
BP	GO:0043605	cellular amide catabolic process	IEP	Predicted GO
CC	GO:0043625	delta DNA polymerase complex	IEP	Predicted GO
CC	GO:0044454	nuclear chromosome part	IEP	Predicted GO
CC	GO:0044463	cell projection part	IEP	Predicted GO
BP	GO:0051103	DNA ligation involved in DNA repair	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
CC	GO:0071020	post-spliceosomal complex	IEP	Predicted GO
BP	GO:0071897	DNA biosynthetic process	IEP	Predicted GO
BP	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	IEP	Predicted GO
CC	GO:0120038	plasma membrane bounded cell projection part	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000432	DNA_mismatch_repair_MutS_C	592	780
IPR007860	DNA_mmatch_repair_MutS_con_dom	8	144
IPR007696	DNA_mismatch_repair_MutS_core	167	534

External Links

PlasmoDB	PB000623.01.0
PlasmoDB	PB301144.00.0
PlasmoDB	PBANKA_080430

PBANKA_0804300 (MSH2-2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation