PBANKA_1031100 (PREX)

Aliases : PREX

Description : SSF56731: 20-02-2019, SSF52540: P-loop containing nucleoside triphosphate hydrolase, SSF53098: Ribonuclease H-like superfamily, SSF56672: 20-02-2019. Pfam domain(s): PF01612: 3'-5' exonuclease, PF13481: AAA domain, PF00476: DNA polymerase family A.

Gene families : OG_01_0001324 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001324_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1031100
Cluster	P. berghei: Cluster_18

Target	Alias	Description	ECC score	Gene Family Method	Actions
PF3D7_1411400	PREX	SSF53098: Ribonuclease H-like superfamily, SSF56672: No...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan predictions
MF	GO:0003676	nucleic acid binding	IEA	PlasmoDB
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003678	DNA helicase activity	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan predictions
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	PlasmoDB
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	Interproscan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	PlasmoDB
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan predictions
BP	GO:0006260	DNA replication	IEA	PlasmoDB
BP	GO:0006261	DNA-dependent DNA replication	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan predictions
MF	GO:0008408	3'-5' exonuclease activity	IEA	PlasmoDB
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
CC	GO:0020011	apicoplast	ISO	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
MF	GO:0004425	indole-3-glycerol-phosphate synthase activity	IEP	Predicted GO
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Predicted GO
MF	GO:0004532	exoribonuclease activity	IEP	Predicted GO
MF	GO:0004534	5'-3' exoribonuclease activity	IEP	Predicted GO
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0007033	vacuole organization	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
MF	GO:0008409	5'-3' exonuclease activity	IEP	Predicted GO
BP	GO:0009889	regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009966	regulation of signal transduction	IEP	Predicted GO
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010646	regulation of cell communication	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
MF	GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	Predicted GO
MF	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
MF	GO:0017069	snRNA binding	IEP	Predicted GO
MF	GO:0017070	U6 snRNA binding	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
CC	GO:0020002	host cell plasma membrane	IEP	Predicted GO
BP	GO:0023051	regulation of signaling	IEP	Predicted GO
CC	GO:0030008	TRAPP complex	IEP	Predicted GO
CC	GO:0030118	clathrin coat	IEP	Predicted GO
CC	GO:0030125	clathrin vesicle coat	IEP	Predicted GO
CC	GO:0030130	clathrin coat of trans-Golgi network vesicle	IEP	Predicted GO
CC	GO:0030132	clathrin coat of coated pit	IEP	Predicted GO
MF	GO:0030276	clathrin binding	IEP	Predicted GO
MF	GO:0030623	U5 snRNA binding	IEP	Predicted GO
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0032012	regulation of ARF protein signal transduction	IEP	Predicted GO
MF	GO:0032051	clathrin light chain binding	IEP	Predicted GO
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0046578	regulation of Ras protein signal transduction	IEP	Predicted GO
BP	GO:0048268	clathrin coat assembly	IEP	Predicted GO
BP	GO:0051056	regulation of small GTPase mediated signal transduction	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Predicted GO
MF	GO:0070403	NAD+ binding	IEP	Predicted GO
CC	GO:0071013	catalytic step 2 spliceosome	IEP	Predicted GO
CC	GO:0071439	clathrin complex	IEP	Predicted GO
CC	GO:0098797	plasma membrane protein complex	IEP	Predicted GO
MF	GO:0140110	transcription regulator activity	IEP	Predicted GO
BP	GO:1902531	regulation of intracellular signal transduction	IEP	Predicted GO
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Predicted GO
CC	GO:1990229	iron-sulfur cluster assembly complex	IEP	Predicted GO
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002562	3'-5'_exonuclease_dom	1240	1411
IPR001098	DNA-dir_DNA_pol_A_palm_dom	1444	1806

External Links

PlasmoDB	PB000754.02.0
PlasmoDB	PB300049.00.0
PlasmoDB	PBANKA_103110

PBANKA_1031100 (PREX)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation