PBANKA_1133300 (EF-1alpha)


Aliases : EF-1alpha

Description : SSF50465: Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, SSF50447: Translation protein, beta-barrel domain superfamily, SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF03144: Elongation factor Tu domain 2, PF00009: Elongation factor Tu GTP binding domain, PF03143: Elongation factor Tu C-terminal domain.


Gene families : OG_01_0000139 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000139_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pbe RNA-seq: PBANKA_1133300
Cluster P. berghei: Cluster_15

Target Alias Description ECC score Gene Family Method Actions
PF3D7_1357000 No alias SSF50465: "Translation elongation factor EF1A/initiation... 0.24 Orthofinderv1.1.8
PF3D7_1357100 No alias SSF50465: "Translation elongation factor EF1A/initiation... 0.24 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0003746 translation elongation factor activity IEA PlasmoDB
MF GO:0003924 GTPase activity IEA Interproscan predictions
MF GO:0003924 GTPase activity IEA PlasmoDB
MF GO:0005525 GTP binding IEA Interproscan predictions
MF GO:0005525 GTP binding IEA PlasmoDB
CC GO:0005737 cytoplasm IEA PlasmoDB
BP GO:0006414 translational elongation IEA PlasmoDB
Type GO Term Name Evidence Source
CC GO:0000015 phosphopyruvate hydratase complex IEP Predicted GO
MF GO:0000287 magnesium ion binding IEP Predicted GO
CC GO:0000323 lytic vacuole IEP Predicted GO
BP GO:0000380 alternative mRNA splicing, via spliceosome IEP Predicted GO
CC GO:0000428 DNA-directed RNA polymerase complex IEP Predicted GO
MF GO:0000900 translation repressor activity, mRNA regulatory element binding IEP Predicted GO
BP GO:0001678 cellular glucose homeostasis IEP Predicted GO
BP GO:0001817 regulation of cytokine production IEP Predicted GO
BP GO:0001818 negative regulation of cytokine production IEP Predicted GO
MF GO:0003688 DNA replication origin binding IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0003938 IMP dehydrogenase activity IEP Predicted GO
MF GO:0004013 adenosylhomocysteinase activity IEP Predicted GO
MF GO:0004177 aminopeptidase activity IEP Predicted GO
MF GO:0004396 hexokinase activity IEP Predicted GO
MF GO:0004416 hydroxyacylglutathione hydrolase activity IEP Predicted GO
MF GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity IEP Predicted GO
MF GO:0004516 nicotinate phosphoribosyltransferase activity IEP Predicted GO
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0004619 phosphoglycerate mutase activity IEP Predicted GO
MF GO:0004634 phosphopyruvate hydratase activity IEP Predicted GO
MF GO:0004731 purine-nucleoside phosphorylase activity IEP Predicted GO
MF GO:0004735 pyrroline-5-carboxylate reductase activity IEP Predicted GO
MF GO:0004743 pyruvate kinase activity IEP Predicted GO
MF GO:0004766 spermidine synthase activity IEP Predicted GO
MF GO:0004828 serine-tRNA ligase activity IEP Predicted GO
MF GO:0005092 GDP-dissociation inhibitor activity IEP Predicted GO
MF GO:0005093 Rab GDP-dissociation inhibitor activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005536 glucose binding IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005764 lysosome IEP Predicted GO
CC GO:0005767 secondary lysosome IEP Predicted GO
CC GO:0005773 vacuole IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005832 chaperonin-containing T-complex IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005853 eukaryotic translation elongation factor 1 complex IEP Predicted GO
CC GO:0005854 nascent polypeptide-associated complex IEP Predicted GO
CC GO:0005856 cytoskeleton IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006089 lactate metabolic process IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006091 generation of precursor metabolites and energy IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006148 inosine catabolic process IEP Predicted GO
BP GO:0006152 purine nucleoside catabolic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006417 regulation of translation IEP Predicted GO
BP GO:0006434 seryl-tRNA aminoacylation IEP Predicted GO
BP GO:0006449 regulation of translational termination IEP Predicted GO
BP GO:0006452 translational frameshifting IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006458 'de novo' protein folding IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006560 proline metabolic process IEP Predicted GO
BP GO:0006561 proline biosynthetic process IEP Predicted GO
BP GO:0006595 polyamine metabolic process IEP Predicted GO
BP GO:0006596 polyamine biosynthetic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006754 ATP biosynthetic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0007264 small GTPase mediated signal transduction IEP Predicted GO
BP GO:0008216 spermidine metabolic process IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008235 metalloexopeptidase activity IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
MF GO:0008238 exopeptidase activity IEP Predicted GO
BP GO:0008295 spermidine biosynthetic process IEP Predicted GO
BP GO:0008593 regulation of Notch signaling pathway IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009145 purine nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009206 purine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009309 amine biosynthetic process IEP Predicted GO
BP GO:0009435 NAD biosynthetic process IEP Predicted GO
BP GO:0009438 methylglyoxal metabolic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009967 positive regulation of signal transduction IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010608 posttranscriptional regulation of gene expression IEP Predicted GO
BP GO:0010647 positive regulation of cell communication IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0015935 small ribosomal subunit IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016801 hydrolase activity, acting on ether bonds IEP Predicted GO
MF GO:0016802 trialkylsulfonium hydrolase activity IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
BP GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEP Predicted GO
BP GO:0019357 nicotinate nucleotide biosynthetic process IEP Predicted GO
BP GO:0019358 nicotinate nucleotide salvage IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019365 pyridine nucleotide salvage IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019439 aromatic compound catabolic process IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019674 NAD metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
CC GO:0020020 food vacuole IEP Predicted GO
BP GO:0020027 hemoglobin metabolic process IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
BP GO:0023056 positive regulation of signaling IEP Predicted GO
CC GO:0030139 endocytic vesicle IEP Predicted GO
MF GO:0030371 translation repressor activity IEP Predicted GO
CC GO:0030880 RNA polymerase complex IEP Predicted GO
MF GO:0030955 potassium ion binding IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0031410 cytoplasmic vesicle IEP Predicted GO
MF GO:0031420 alkali metal ion binding IEP Predicted GO
CC GO:0031982 vesicle IEP Predicted GO
CC GO:0032010 phagolysosome IEP Predicted GO
BP GO:0032270 positive regulation of cellular protein metabolic process IEP Predicted GO
BP GO:0032675 regulation of interleukin-6 production IEP Predicted GO
BP GO:0032715 negative regulation of interleukin-6 production IEP Predicted GO
BP GO:0032780 negative regulation of ATPase activity IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033500 carbohydrate homeostasis IEP Predicted GO
BP GO:0034248 regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034250 positive regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034404 nucleobase-containing small molecule biosynthetic process IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034655 nucleobase-containing compound catabolic process IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
BP GO:0042026 protein refolding IEP Predicted GO
BP GO:0042182 ketone catabolic process IEP Predicted GO
BP GO:0042401 cellular biogenic amine biosynthetic process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
BP GO:0042540 hemoglobin catabolic process IEP Predicted GO
BP GO:0042593 glucose homeostasis IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
BP GO:0043173 nucleotide salvage IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043243 positive regulation of protein complex disassembly IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0043462 regulation of ATPase activity IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0044270 cellular nitrogen compound catabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
MF GO:0045182 translation regulator activity IEP Predicted GO
CC GO:0045335 phagocytic vesicle IEP Predicted GO
BP GO:0045727 positive regulation of translation IEP Predicted GO
BP GO:0045747 positive regulation of Notch signaling pathway IEP Predicted GO
BP GO:0045901 positive regulation of translational elongation IEP Predicted GO
BP GO:0045905 positive regulation of translational termination IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046034 ATP metabolic process IEP Predicted GO
BP GO:0046102 inosine metabolic process IEP Predicted GO
BP GO:0046130 purine ribonucleoside catabolic process IEP Predicted GO
BP GO:0046185 aldehyde catabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046434 organophosphate catabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046497 nicotinate nucleotide metabolic process IEP Predicted GO
BP GO:0046700 heterocycle catabolic process IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
MF GO:0048029 monosaccharide binding IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
BP GO:0048584 positive regulation of response to stimulus IEP Predicted GO
MF GO:0050661 NADP binding IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051083 'de novo' cotranslational protein folding IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
BP GO:0051239 regulation of multicellular organismal process IEP Predicted GO
BP GO:0051241 negative regulation of multicellular organismal process IEP Predicted GO
BP GO:0051247 positive regulation of protein metabolic process IEP Predicted GO
BP GO:0051596 methylglyoxal catabolic process IEP Predicted GO
CC GO:0055029 nuclear DNA-directed RNA polymerase complex IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
CC GO:0061695 transferase complex, transferring phosphorus-containing groups IEP Predicted GO
BP GO:0061727 methylglyoxal catabolic process to lactate IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072523 purine-containing compound catabolic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Predicted GO
MF GO:0090079 translation regulator activity, nucleic acid binding IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
CC GO:0097708 intracellular vesicle IEP Predicted GO
CC GO:0101031 chaperone complex IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
BP GO:1901292 nucleoside phosphate catabolic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901361 organic cyclic compound catabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR004160 Transl_elong_EFTu/EF1A_C 320 427
IPR004161 EFTu-like_2 246 311
IPR000795 TF_GTP-bd_dom 5 220