PBANKA_1138300 (TMCO1)

Aliases : TMCO1

Description : No superfamily available. Pfam domain(s): PF01956: Integral membrane protein EMC3/TMCO1-like.

Gene families : OG_01_0001516 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001516_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1138300
Cluster	P. berghei: Cluster_20

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005216	ion channel activity	None	Extended
MF	GO:0005261	cation channel activity	None	Extended
MF	GO:0005262	calcium channel activity	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006873	cellular ion homeostasis	None	Extended
BP	GO:0006874	cellular calcium ion homeostasis	None	Extended
BP	GO:0006875	cellular metal ion homeostasis	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008324	cation transmembrane transporter activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0015075	ion transmembrane transporter activity	None	Extended
MF	GO:0015085	calcium ion transmembrane transporter activity	None	Extended
MF	GO:0015267	channel activity	None	Extended
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	None	Extended
CC	GO:0016020	membrane	IEA	Interproscan predictions
CC	GO:0016020	membrane	IEA	PlasmoDB
CC	GO:0016021	integral component of membrane	None	Extended
BP	GO:0019725	cellular homeostasis	None	Extended
MF	GO:0022803	passive transmembrane transporter activity	None	Extended
MF	GO:0022838	substrate-specific channel activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0022890	inorganic cation transmembrane transporter activity	None	Extended
BP	GO:0030003	cellular cation homeostasis	None	Extended
CC	GO:0030176	integral component of endoplasmic reticulum membrane	IEA	PlasmoDB
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	None	Extended
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	IEA	PlasmoDB
BP	GO:0042592	homeostatic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044432	endoplasmic reticulum part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046873	metal ion transmembrane transporter activity	None	Extended
BP	GO:0048878	chemical homeostasis	None	Extended
BP	GO:0050801	ion homeostasis	None	Extended
BP	GO:0055065	metal ion homeostasis	None	Extended
BP	GO:0055074	calcium ion homeostasis	None	Extended
BP	GO:0055080	cation homeostasis	None	Extended
BP	GO:0055082	cellular chemical homeostasis	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
BP	GO:0072503	cellular divalent inorganic cation homeostasis	None	Extended
BP	GO:0072507	divalent inorganic cation homeostasis	None	Extended
BP	GO:0098771	inorganic ion homeostasis	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
MF	GO:0000287	magnesium ion binding	IEP	Predicted GO
CC	GO:0000408	EKC/KEOPS complex	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0004146	dihydrofolate reductase activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004448	isocitrate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004450	isocitrate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004725	protein tyrosine phosphatase activity	IEP	Predicted GO
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Predicted GO
MF	GO:0004799	thymidylate synthase activity	IEP	Predicted GO
MF	GO:0005381	iron ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005385	zinc ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005768	endosome	IEP	Predicted GO
CC	GO:0005787	signal peptidase complex	IEP	Predicted GO
CC	GO:0005956	protein kinase CK2 complex	IEP	Predicted GO
CC	GO:0005971	ribonucleoside-diphosphate reductase complex	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006102	isocitrate metabolic process	IEP	Predicted GO
BP	GO:0006119	oxidative phosphorylation	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006231	dTMP biosynthetic process	IEP	Predicted GO
BP	GO:0006465	signal peptide processing	IEP	Predicted GO
BP	GO:0006730	one-carbon metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006760	folic acid-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
CC	GO:0008541	proteasome regulatory particle, lid subcomplex	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015672	monovalent inorganic cation transport	IEP	Predicted GO
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Predicted GO
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
BP	GO:0016571	histone methylation	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Predicted GO
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Predicted GO
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
BP	GO:0018022	peptidyl-lysine methylation	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
MF	GO:0019829	cation-transporting ATPase activity	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
MF	GO:0019904	protein domain specific binding	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0022853	active ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0030677	ribonuclease P complex	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0033180	proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
BP	GO:0034220	ion transmembrane transport	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0034968	histone lysine methylation	IEP	Predicted GO
MF	GO:0035064	methylated histone binding	IEP	Predicted GO
MF	GO:0036442	proton-exporting ATPase activity	IEP	Predicted GO
MF	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	IEP	Predicted GO
MF	GO:0042393	histone binding	IEP	Predicted GO
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042559	pteridine-containing compound biosynthetic process	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
MF	GO:0042625	ATPase coupled ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0044437	vacuolar part	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
MF	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	IEP	Predicted GO
BP	GO:0046034	ATP metabolic process	IEP	Predicted GO
BP	GO:0046073	dTMP metabolic process	IEP	Predicted GO
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046653	tetrahydrofolate metabolic process	IEP	Predicted GO
BP	GO:0046654	tetrahydrofolate biosynthetic process	IEP	Predicted GO
MF	GO:0046915	transition metal ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	IEP	Predicted GO
MF	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEP	Predicted GO
CC	GO:0048471	perinuclear region of cytoplasm	IEP	Predicted GO
MF	GO:0051287	NAD binding	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Predicted GO
BP	GO:0071344	diphosphate metabolic process	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
MF	GO:0072509	divalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0098655	cation transmembrane transport	IEP	Predicted GO
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Predicted GO
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Predicted GO
MF	GO:0140030	modification-dependent protein binding	IEP	Predicted GO
MF	GO:0140034	methylation-dependent protein binding	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
CC	GO:1902555	endoribonuclease complex	IEP	Predicted GO
BP	GO:1902600	proton transmembrane transport	IEP	Predicted GO
CC	GO:1905348	endonuclease complex	IEP	Predicted GO
CC	GO:1990204	oxidoreductase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002809	EMC3/TMCO1	12	173

External Links

PlasmoDB	PB000752.02.0
PlasmoDB	PBANKA_113830

PBANKA_1138300 (TMCO1)

Expression Profile

Co-expression Networks

Functional Annotation