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  5. PBANKA_1321200

PBANKA_1321200 (VPS4)


Aliases : VPS4

Description : SSF116846: MIT domain superfamily, SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF09336: Vps4 C terminal oligomerisation domain, PF04212: MIT (microtubule interacting and transport) domain, PF00004: ATPase family associated with various cellular activities (AAA).


Gene families : OG_01_0001817 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001817_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pbe RNA-seq: PBANKA_1321200
Cluster P. berghei: Cluster_40

Target Alias Description ECC score Gene Family Method Actions
PF3D7_1457500 VPS4 SSF52540: P-loop containing nucleoside triphosphate... 0.03 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan predictions
MF GO:0005524 ATP binding IEA PlasmoDB
CC GO:0005737 cytoplasm ISO PlasmoDB
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Type GO Term Name Evidence Source
BP GO:0000045 autophagosome assembly IEP Predicted GO
MF GO:0000104 succinate dehydrogenase activity IEP Predicted GO
CC GO:0000159 protein phosphatase type 2A complex IEP Predicted GO
CC GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain IEP Predicted GO
BP GO:0001505 regulation of neurotransmitter levels IEP Predicted GO
MF GO:0003684 damaged DNA binding IEP Predicted GO
MF GO:0003756 protein disulfide isomerase activity IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0003994 aconitate hydratase activity IEP Predicted GO
MF GO:0004140 dephospho-CoA kinase activity IEP Predicted GO
MF GO:0004146 dihydrofolate reductase activity IEP Predicted GO
MF GO:0004345 glucose-6-phosphate dehydrogenase activity IEP Predicted GO
MF GO:0004352 glutamate dehydrogenase (NAD+) activity IEP Predicted GO
MF GO:0004353 glutamate dehydrogenase [NAD(P)+] activity IEP Predicted GO
MF GO:0004372 glycine hydroxymethyltransferase activity IEP Predicted GO
MF GO:0004652 polynucleotide adenylyltransferase activity IEP Predicted GO
MF GO:0004722 protein serine/threonine phosphatase activity IEP Predicted GO
MF GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEP Predicted GO
MF GO:0004799 thymidylate synthase activity IEP Predicted GO
MF GO:0005096 GTPase activator activity IEP Predicted GO
CC GO:0005739 mitochondrion IEP Predicted GO
CC GO:0005750 mitochondrial respiratory chain complex III IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
CC GO:0005789 endoplasmic reticulum membrane IEP Predicted GO
CC GO:0005802 trans-Golgi network IEP Predicted GO
CC GO:0005813 centrosome IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005971 ribonucleoside-diphosphate reductase complex IEP Predicted GO
BP GO:0005996 monosaccharide metabolic process IEP Predicted GO
BP GO:0006006 glucose metabolic process IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006098 pentose-phosphate shunt IEP Predicted GO
BP GO:0006099 tricarboxylic acid cycle IEP Predicted GO
BP GO:0006101 citrate metabolic process IEP Predicted GO
BP GO:0006103 2-oxoglutarate metabolic process IEP Predicted GO
BP GO:0006106 fumarate metabolic process IEP Predicted GO
BP GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006231 dTMP biosynthetic process IEP Predicted GO
BP GO:0006275 regulation of DNA replication IEP Predicted GO
BP GO:0006536 glutamate metabolic process IEP Predicted GO
BP GO:0006538 glutamate catabolic process IEP Predicted GO
BP GO:0006544 glycine metabolic process IEP Predicted GO
BP GO:0006545 glycine biosynthetic process IEP Predicted GO
BP GO:0006563 L-serine metabolic process IEP Predicted GO
BP GO:0006575 cellular modified amino acid metabolic process IEP Predicted GO
BP GO:0006611 protein export from nucleus IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006730 one-carbon metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006739 NADP metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006760 folic acid-containing compound metabolic process IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006811 ion transport IEP Predicted GO
BP GO:0006820 anion transport IEP Predicted GO
BP GO:0006848 pyruvate transport IEP Predicted GO
BP GO:0006850 mitochondrial pyruvate transmembrane transport IEP Predicted GO
BP GO:0007029 endoplasmic reticulum organization IEP Predicted GO
BP GO:0007033 vacuole organization IEP Predicted GO
MF GO:0008121 ubiquinol-cytochrome-c reductase activity IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008177 succinate dehydrogenase (ubiquinone) activity IEP Predicted GO
BP GO:0008272 sulfate transport IEP Predicted GO
CC GO:0008287 protein serine/threonine phosphatase complex IEP Predicted GO
MF GO:0008483 transaminase activity IEP Predicted GO
MF GO:0008696 4-amino-4-deoxychorismate lyase activity IEP Predicted GO
MF GO:0009055 electron transfer activity IEP Predicted GO
BP GO:0009063 cellular amino acid catabolic process IEP Predicted GO
BP GO:0009065 glutamine family amino acid catabolic process IEP Predicted GO
BP GO:0009069 serine family amino acid metabolic process IEP Predicted GO
BP GO:0009070 serine family amino acid biosynthetic process IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009129 pyrimidine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009157 deoxyribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009162 deoxyribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009219 pyrimidine deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009262 deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009263 deoxyribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009265 2'-deoxyribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009394 2'-deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009396 folic acid-containing compound biosynthetic process IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015077 monovalent inorganic cation transmembrane transporter activity IEP Predicted GO
MF GO:0015078 proton transmembrane transporter activity IEP Predicted GO
MF GO:0015103 inorganic anion transmembrane transporter activity IEP Predicted GO
MF GO:0015116 sulfate transmembrane transporter activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
MF GO:0015399 primary active transmembrane transporter activity IEP Predicted GO
MF GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity IEP Predicted GO
BP GO:0015672 monovalent inorganic cation transport IEP Predicted GO
BP GO:0015698 inorganic anion transport IEP Predicted GO
BP GO:0015936 coenzyme A metabolic process IEP Predicted GO
BP GO:0015937 coenzyme A biosynthetic process IEP Predicted GO
BP GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient IEP Predicted GO
BP GO:0015991 ATP hydrolysis coupled proton transport IEP Predicted GO
CC GO:0016020 membrane IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
BP GO:0016054 organic acid catabolic process IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor IEP Predicted GO
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEP Predicted GO
MF GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IEP Predicted GO
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors IEP Predicted GO
MF GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor IEP Predicted GO
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Predicted GO
MF GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor IEP Predicted GO
MF GO:0016742 hydroxymethyl-, formyl- and related transferase activity IEP Predicted GO
MF GO:0016769 transferase activity, transferring nitrogenous groups IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016833 oxo-acid-lyase activity IEP Predicted GO
MF GO:0016860 intramolecular oxidoreductase activity IEP Predicted GO
MF GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds IEP Predicted GO
BP GO:0016999 antibiotic metabolic process IEP Predicted GO
MF GO:0017057 6-phosphogluconolactonase activity IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
BP GO:0019264 glycine biosynthetic process from serine IEP Predicted GO
BP GO:0019318 hexose metabolic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019551 glutamate catabolic process to 2-oxoglutarate IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019692 deoxyribose phosphate metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
MF GO:0019829 cation-transporting ATPase activity IEP Predicted GO
MF GO:0019904 protein domain specific binding IEP Predicted GO
MF GO:0022804 active transmembrane transporter activity IEP Predicted GO
MF GO:0022853 active ion transmembrane transporter activity IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0030234 enzyme regulator activity IEP Predicted GO
MF GO:0030337 DNA polymerase processivity factor activity IEP Predicted GO
CC GO:0031984 organelle subcompartment IEP Predicted GO
CC GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain IEP Predicted GO
CC GO:0033180 proton-transporting V-type ATPase, V1 domain IEP Predicted GO
BP GO:0033866 nucleoside bisphosphate biosynthetic process IEP Predicted GO
BP GO:0034030 ribonucleoside bisphosphate biosynthetic process IEP Predicted GO
BP GO:0034033 purine nucleoside bisphosphate biosynthetic process IEP Predicted GO
BP GO:0034220 ion transmembrane transport IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0035999 tetrahydrofolate interconversion IEP Predicted GO
MF GO:0036442 proton-exporting ATPase activity IEP Predicted GO
MF GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity IEP Predicted GO
BP GO:0042133 neurotransmitter metabolic process IEP Predicted GO
BP GO:0042136 neurotransmitter biosynthetic process IEP Predicted GO
BP GO:0042558 pteridine-containing compound metabolic process IEP Predicted GO
BP GO:0042559 pteridine-containing compound biosynthetic process IEP Predicted GO
BP GO:0042592 homeostatic process IEP Predicted GO
MF GO:0042625 ATPase coupled ion transmembrane transporter activity IEP Predicted GO
MF GO:0042626 ATPase activity, coupled to transmembrane movement of substances IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
MF GO:0043492 ATPase activity, coupled to movement of substances IEP Predicted GO
BP GO:0043631 RNA polyadenylation IEP Predicted GO
BP GO:0043648 dicarboxylic acid metabolic process IEP Predicted GO
BP GO:0043649 dicarboxylic acid catabolic process IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
CC GO:0044432 endoplasmic reticulum part IEP Predicted GO
CC GO:0044437 vacuolar part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
MF GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism IEP Predicted GO
CC GO:0045275 respiratory chain complex III IEP Predicted GO
BP GO:0045454 cell redox homeostasis IEP Predicted GO
BP GO:0046073 dTMP metabolic process IEP Predicted GO
BP GO:0046385 deoxyribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046395 carboxylic acid catabolic process IEP Predicted GO
BP GO:0046416 D-amino acid metabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046653 tetrahydrofolate metabolic process IEP Predicted GO
BP GO:0046654 tetrahydrofolate biosynthetic process IEP Predicted GO
MF GO:0046961 proton-transporting ATPase activity, rotational mechanism IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
BP GO:0051052 regulation of DNA metabolic process IEP Predicted GO
BP GO:0051156 glucose 6-phosphate metabolic process IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
MF GO:0051536 iron-sulfur cluster binding IEP Predicted GO
MF GO:0051537 2 iron, 2 sulfur cluster binding IEP Predicted GO
MF GO:0051540 metal cluster binding IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
MF GO:0061731 ribonucleoside-diphosphate reductase activity IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
BP GO:0065008 regulation of biological quality IEP Predicted GO
CC GO:0070069 cytochrome complex IEP Predicted GO
BP GO:0070178 D-serine metabolic process IEP Predicted GO
MF GO:0070566 adenylyltransferase activity IEP Predicted GO
CC GO:0071782 endoplasmic reticulum tubular network IEP Predicted GO
BP GO:0071786 endoplasmic reticulum tubular network organization IEP Predicted GO
BP GO:0072348 sulfur compound transport IEP Predicted GO
BP GO:0072350 tricarboxylic acid metabolic process IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
BP GO:0090662 ATP hydrolysis coupled transmembrane transport IEP Predicted GO
BP GO:0098655 cation transmembrane transport IEP Predicted GO
BP GO:0098660 inorganic ion transmembrane transport IEP Predicted GO
BP GO:0098662 inorganic cation transmembrane transport IEP Predicted GO
MF GO:0098772 molecular function regulator IEP Predicted GO
CC GO:0098791 Golgi subcompartment IEP Predicted GO
CC GO:0098803 respiratory chain complex IEP Predicted GO
CC GO:0098827 endoplasmic reticulum subcompartment IEP Predicted GO
BP GO:0099131 ATP hydrolysis coupled ion transmembrane transport IEP Predicted GO
BP GO:0099132 ATP hydrolysis coupled cation transmembrane transport IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901475 pyruvate transmembrane transport IEP Predicted GO
BP GO:1901605 alpha-amino acid metabolic process IEP Predicted GO
BP GO:1901606 alpha-amino acid catabolic process IEP Predicted GO
MF GO:1901682 sulfur compound transmembrane transporter activity IEP Predicted GO
CC GO:1902494 catalytic complex IEP Predicted GO
BP GO:1902600 proton transmembrane transport IEP Predicted GO
CC GO:1903293 phosphatase complex IEP Predicted GO
BP GO:1905037 autophagosome organization IEP Predicted GO
CC GO:1990204 oxidoreductase complex IEP Predicted GO
InterPro domains Description Start Stop
IPR015415 Vps4_C 364 426
IPR007330 MIT 9 72
IPR003959 ATPase_AAA_core 150 279
PlasmoDB PB000159.01.0
PlasmoDB PBANKA_132120